JPS567760A - Novel n-substituted phenoxypropylamide compound - Google Patents

Novel n-substituted phenoxypropylamide compound

Info

Publication number
JPS567760A
JPS567760A JP8342679A JP8342679A JPS567760A JP S567760 A JPS567760 A JP S567760A JP 8342679 A JP8342679 A JP 8342679A JP 8342679 A JP8342679 A JP 8342679A JP S567760 A JPS567760 A JP S567760A
Authority
JP
Japan
Prior art keywords
compound
formula
substituted
phenoxypropylamide
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8342679A
Other languages
Japanese (ja)
Other versions
JPS609750B2 (en
Inventor
Takeo Shibata
Toshihisa Itaya
Nobuaki Yamagoshi
Shigeru Kurata
Naoyuki Koizumi
Masao Taruya
Hideki Sakuma
Kunihiro Konishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP54083426A priority Critical patent/JPS609750B2/en
Application filed by Teikoku Hormone Manufacturing Co Ltd filed Critical Teikoku Hormone Manufacturing Co Ltd
Priority to US06/164,017 priority patent/US4293557A/en
Priority to EP80103742A priority patent/EP0024510B1/en
Priority to DE8080103742T priority patent/DE3065362D1/en
Publication of JPS567760A publication Critical patent/JPS567760A/en
Publication of JPS609750B2 publication Critical patent/JPS609750B2/en
Priority to IN537/MAS/86A priority patent/IN163755B/en
Priority to SG758/86A priority patent/SG75886G/en
Priority to KE367086A priority patent/KE3670A/en
Priority to HK953/86A priority patent/HK95386A/en
Priority to MY563/87A priority patent/MY8700563A/en
Expired legal-status Critical Current

Links

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  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:N-Substituted phenoxypropylamide compounds of formula I [R is H, CH3, or C2H5; Y is 1-pyrrolidinyl, 1-piperidinyl, 1-perhydroazepinyl and 1- perhydroazocinyl which may have substitution groups (OH or CH2 OH); Z is H, or CH3 or C2H5 which may have substitution groups (OH or NH2); provided that R is C2H5 when Y is unsubstituted 1-pyrrolidinyl] and their salts.
EXAMPLE: N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl] formamide.
USE: Antiulcerative agents having excellent inhibitory activity of gastric acid secretion owing to the antagonistic activity to histamine H2-acceptor.
PROCESS: A compound of formula I is obtained by the reaction of novel compound of formula II and a compound of formula Z-COOH or their reactive derivatives. The compound of formula II can be obtained by the reaction of a compound of formula III with a compound of formula Y'-H(Y' is non-substituted Y).
COPYRIGHT: (C)1981,JPO&Japio
JP54083426A 1979-07-03 1979-07-03 Novel N-substituted phenoxypropylamide compounds Expired JPS609750B2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP54083426A JPS609750B2 (en) 1979-07-03 1979-07-03 Novel N-substituted phenoxypropylamide compounds
US06/164,017 US4293557A (en) 1979-07-03 1980-06-30 Antiulcer phenoxypropylamine derivatives
EP80103742A EP0024510B1 (en) 1979-07-03 1980-07-01 Phenoxypropyl amine derivatives, process for their preparation, and pharmaceutical compositions containing them
DE8080103742T DE3065362D1 (en) 1979-07-03 1980-07-01 Phenoxypropyl amine derivatives, process for their preparation, and pharmaceutical compositions containing them
IN537/MAS/86A IN163755B (en) 1979-07-03 1986-07-15
SG758/86A SG75886G (en) 1979-07-03 1986-09-19 Phenoxypropyl amine derivatives, process for their preparation, and pharmaceutical compositions containing them
KE367086A KE3670A (en) 1979-07-03 1986-10-14 Phenoxypropyl amine derivatives,process for their preparation,and pharmaceutical compositions containing them
HK953/86A HK95386A (en) 1979-07-03 1986-12-11 Phenoxypropyl amine derivatives,process for their preparation,and pharmaceutical compositions containing them
MY563/87A MY8700563A (en) 1979-07-03 1987-12-30 Phenoxypropyl amine derivatives process for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54083426A JPS609750B2 (en) 1979-07-03 1979-07-03 Novel N-substituted phenoxypropylamide compounds

Publications (2)

Publication Number Publication Date
JPS567760A true JPS567760A (en) 1981-01-27
JPS609750B2 JPS609750B2 (en) 1985-03-12

Family

ID=13802105

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54083426A Expired JPS609750B2 (en) 1979-07-03 1979-07-03 Novel N-substituted phenoxypropylamide compounds

Country Status (1)

Country Link
JP (1) JPS609750B2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53149936A (en) * 1977-05-17 1978-12-27 Allen & Hanburys Ltd Novel aminoalkylbenzene derivative process for preparing same medical composition and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53149936A (en) * 1977-05-17 1978-12-27 Allen & Hanburys Ltd Novel aminoalkylbenzene derivative process for preparing same medical composition and application thereof

Also Published As

Publication number Publication date
JPS609750B2 (en) 1985-03-12

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