JPS56108764A - Novel synthesis of beta-blocker - Google Patents
Novel synthesis of beta-blockerInfo
- Publication number
- JPS56108764A JPS56108764A JP1039980A JP1039980A JPS56108764A JP S56108764 A JPS56108764 A JP S56108764A JP 1039980 A JP1039980 A JP 1039980A JP 1039980 A JP1039980 A JP 1039980A JP S56108764 A JPS56108764 A JP S56108764A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- blocker
- beta
- inert solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002876 beta blocker Substances 0.000 title abstract 2
- 229940097320 beta blocking agent Drugs 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002841 Lewis acid Substances 0.000 abstract 2
- SJRJJKPEHAURKC-UHFFFAOYSA-N N-Methylmorpholine Chemical compound CN1CCOCC1 SJRJJKPEHAURKC-UHFFFAOYSA-N 0.000 abstract 2
- LWBPNIJBHRISSS-UHFFFAOYSA-L beryllium dichloride Chemical compound Cl[Be]Cl LWBPNIJBHRISSS-UHFFFAOYSA-L 0.000 abstract 2
- 239000012442 inert solvent Substances 0.000 abstract 2
- 150000007517 lewis acids Chemical class 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229910001627 beryllium chloride Inorganic materials 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- PHUTUTUABXHXLW-UHFFFAOYSA-N pindolol Chemical compound CC(C)NCC(O)COC1=CC=CC2=NC=C[C]12 PHUTUTUABXHXLW-UHFFFAOYSA-N 0.000 abstract 1
- 229960002508 pindolol Drugs 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- -1 tetrahydroindole-spirodioxolane compound Chemical class 0.000 abstract 1
- FAQYAMRNWDIXMY-UHFFFAOYSA-N trichloroborane Chemical compound ClB(Cl)Cl FAQYAMRNWDIXMY-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1039980A JPS56108764A (en) | 1980-01-30 | 1980-01-30 | Novel synthesis of beta-blocker |
| CA000346987A CA1139760A (en) | 1979-03-07 | 1980-03-04 | 1,4-dioxaspiro¬4,5| decene compounds |
| US06/127,521 US4506079A (en) | 1979-03-07 | 1980-03-05 | Process for preparing indoles |
| CH178780A CH646968A5 (de) | 1979-03-07 | 1980-03-06 | 1,4-dioxaspiro(4,5)decen-verbindungen sowie verfahren zur herstellung von 2-hydroxy-3-substituierten propylarylaethern. |
| FR8005051A FR2450829A1 (fr) | 1979-03-07 | 1980-03-06 | Procede de preparation de composes de 1,4-dioxaspiro-(4,5)decene et nouveaux produits ainsi obtenus |
| GB8007793A GB2058745B (en) | 1979-03-07 | 1980-03-07 | 1,4-dioxospiro(4,5)decene compounds |
| DE19803008902 DE3008902A1 (de) | 1979-03-07 | 1980-03-07 | 1,4-dioxaspiro eckige klammer auf 4,5 eckige klammer zu decen-derivate |
| IT67367/80A IT1129805B (it) | 1979-03-07 | 1980-03-07 | Composti dell'1 4 diossaspiro 4 5 de cene particolarmente utili come in termedi per la preparazione di beta bloccanti clinici |
| HU20281A HU183321B (en) | 1980-01-30 | 1981-01-29 | Process for preparing indole derivatives with beta-blocking activity |
| PL22946181A PL229461A1 (enrdf_load_stackoverflow) | 1980-01-30 | 1981-01-30 | |
| CA000407793A CA1180326A (en) | 1979-03-07 | 1982-07-21 | 1,4-dioxaspiro[4,5]decene compounds |
| US06/684,090 US4582905A (en) | 1979-03-07 | 1984-12-20 | 1,4-Dioxaspiro(4,5)decene compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1039980A JPS56108764A (en) | 1980-01-30 | 1980-01-30 | Novel synthesis of beta-blocker |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56108764A true JPS56108764A (en) | 1981-08-28 |
| JPS6345380B2 JPS6345380B2 (enrdf_load_stackoverflow) | 1988-09-09 |
Family
ID=11749049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1039980A Granted JPS56108764A (en) | 1979-03-07 | 1980-01-30 | Novel synthesis of beta-blocker |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS56108764A (enrdf_load_stackoverflow) |
| HU (1) | HU183321B (enrdf_load_stackoverflow) |
| PL (1) | PL229461A1 (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102499876B1 (ko) * | 2018-11-21 | 2023-02-13 | 엘지디스플레이 주식회사 | 표시 장치 및 타일링 표시 장치 |
| WO2020178911A1 (ja) * | 2019-03-01 | 2020-09-10 | 三菱電機株式会社 | マルチディスプレイシステムおよび映像表示装置 |
| KR102642789B1 (ko) * | 2019-07-31 | 2024-02-29 | 엘지디스플레이 주식회사 | 표시 장치 |
-
1980
- 1980-01-30 JP JP1039980A patent/JPS56108764A/ja active Granted
-
1981
- 1981-01-29 HU HU20281A patent/HU183321B/hu not_active IP Right Cessation
- 1981-01-30 PL PL22946181A patent/PL229461A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6345380B2 (enrdf_load_stackoverflow) | 1988-09-09 |
| HU183321B (en) | 1984-04-28 |
| PL229461A1 (enrdf_load_stackoverflow) | 1981-10-16 |
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