JPS5576858A - 24-fluoro-25-hydroxyvitamin d3 or its oh-protected derivative, and their preparation - Google Patents
24-fluoro-25-hydroxyvitamin d3 or its oh-protected derivative, and their preparationInfo
- Publication number
- JPS5576858A JPS5576858A JP14903178A JP14903178A JPS5576858A JP S5576858 A JPS5576858 A JP S5576858A JP 14903178 A JP14903178 A JP 14903178A JP 14903178 A JP14903178 A JP 14903178A JP S5576858 A JPS5576858 A JP S5576858A
- Authority
- JP
- Japan
- Prior art keywords
- fluoro
- protected derivative
- hydroxyvitamin
- preparation
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- KQNFHJVZTSIZIE-KAKHRBHPSA-N (6r)-6-[(9s,10r,13r,14r,17r)-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-17-yl]-3-fluoro-2-methylheptan-2-ol Chemical compound C1CCC[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@H](CCC(F)C(C)(C)O)C)CC[C@H]33)C)C3=CC=C21 KQNFHJVZTSIZIE-KAKHRBHPSA-N 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 230000001678 irradiating effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14903178A JPS5576858A (en) | 1978-12-04 | 1978-12-04 | 24-fluoro-25-hydroxyvitamin d3 or its oh-protected derivative, and their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14903178A JPS5576858A (en) | 1978-12-04 | 1978-12-04 | 24-fluoro-25-hydroxyvitamin d3 or its oh-protected derivative, and their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5576858A true JPS5576858A (en) | 1980-06-10 |
| JPS6148499B2 JPS6148499B2 (enrdf_load_stackoverflow) | 1986-10-24 |
Family
ID=15466147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP14903178A Granted JPS5576858A (en) | 1978-12-04 | 1978-12-04 | 24-fluoro-25-hydroxyvitamin d3 or its oh-protected derivative, and their preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5576858A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5852268A (ja) * | 1981-08-28 | 1983-03-28 | エフ・ホフマン―ラ ロシユ アーゲー | コレカルシフエロ−ル誘導体 |
| FR2530624A1 (fr) * | 1982-07-26 | 1984-01-27 | Wisconsin Alumni Res Found | Nouveaux analogues de la vitamine d et compositions pharmaceutiques ou veterinaires les contenant |
-
1978
- 1978-12-04 JP JP14903178A patent/JPS5576858A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5852268A (ja) * | 1981-08-28 | 1983-03-28 | エフ・ホフマン―ラ ロシユ アーゲー | コレカルシフエロ−ル誘導体 |
| FR2530624A1 (fr) * | 1982-07-26 | 1984-01-27 | Wisconsin Alumni Res Found | Nouveaux analogues de la vitamine d et compositions pharmaceutiques ou veterinaires les contenant |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6148499B2 (enrdf_load_stackoverflow) | 1986-10-24 |
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