JPS5622763A - 25-hydroxy-24-oxovitamin d3, or its hydroxyl-protecting derivative and its preparation - Google Patents

25-hydroxy-24-oxovitamin d3, or its hydroxyl-protecting derivative and its preparation

Info

Publication number
JPS5622763A
JPS5622763A JP9810679A JP9810679A JPS5622763A JP S5622763 A JPS5622763 A JP S5622763A JP 9810679 A JP9810679 A JP 9810679A JP 9810679 A JP9810679 A JP 9810679A JP S5622763 A JPS5622763 A JP S5622763A
Authority
JP
Japan
Prior art keywords
oxovitamin
hydroxy
compound shown
formula
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9810679A
Other languages
Japanese (ja)
Other versions
JPS6258351B2 (en
Inventor
Osamu Nishikawa
Kenji Ishimaru
Toru Takeshita
Hideki Tsuruta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP9810679A priority Critical patent/JPS5622763A/en
Priority to CA000345624A priority patent/CA1138859A/en
Priority to EP80300426A priority patent/EP0015122B1/en
Priority to DK063080A priority patent/DK162648C/en
Priority to DE8080300426T priority patent/DE3064789D1/en
Priority to DE8282200223T priority patent/DE3069391D1/en
Priority to EP82200223A priority patent/EP0055999B1/en
Priority to US06/121,857 priority patent/US4292249A/en
Publication of JPS5622763A publication Critical patent/JPS5622763A/en
Priority to DK233585A priority patent/DK233585A/en
Publication of JPS6258351B2 publication Critical patent/JPS6258351B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

NEW MATERIAL:A 25-hydroxy-24-oxovitamin D3 shown by the formula I (R1 and R3 are H or OH-protecting group; R2 is H, OH, or OH-protecting group) and its OH-protected derivative.
EXAMPLE: 25-Hydroxy-24-oxovitamin D3.
USE: A vitamin D3 like pharmacologically active agent and a synthetic intermediate for other active type vitamin D3.
PROCESS: A compound shown by the formula II is irradiated by ultraviolet light with wavelength about 200W360nm, preferably 260W310nm to give a compound shown by the formula III. The reaction is carried out at -20W120°C, preferably -10W 50°C. The compound shown by the formula III is isomerized by thermal energy at 20W120°C, preferably at 40W100°C. Both the reactions are preferably carried out in an inert organic solvent, e.g., hexane, etc.
COPYRIGHT: (C)1981,JPO&Japio
JP9810679A 1979-02-15 1979-08-02 25-hydroxy-24-oxovitamin d3, or its hydroxyl-protecting derivative and its preparation Granted JPS5622763A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP9810679A JPS5622763A (en) 1979-08-02 1979-08-02 25-hydroxy-24-oxovitamin d3, or its hydroxyl-protecting derivative and its preparation
DE8282200223T DE3069391D1 (en) 1979-02-15 1980-02-14 Vitamin d3
EP80300426A EP0015122B1 (en) 1979-02-15 1980-02-14 New 25-hydroxy-24-oxocholestane derivatives and preparation thereof
DK063080A DK162648C (en) 1979-02-15 1980-02-14 3BETA, 25-DIHYDROXY-24-OXOCHOLEST-5-ONE DERIVATIVES AND PROCEDURES FOR PREPARING IT
DE8080300426T DE3064789D1 (en) 1979-02-15 1980-02-14 New 25-hydroxy-24-oxocholestane derivatives and preparation thereof
CA000345624A CA1138859A (en) 1979-02-15 1980-02-14 25-hydroxy-24-oxocholestane derivatives and preparation thereof
EP82200223A EP0055999B1 (en) 1979-02-15 1980-02-14 Vitamin d3
US06/121,857 US4292249A (en) 1979-02-15 1980-02-15 25-Hydroxy-24-oxocholestane derivatives and preparation thereof
DK233585A DK233585A (en) 1979-02-15 1985-05-24 ANALOGY PROCEDURE FOR PREPARING 25-HYDROXY-24-OXOCHOLECALCIFEROLS AND INTERMEDIATES FOR USE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9810679A JPS5622763A (en) 1979-08-02 1979-08-02 25-hydroxy-24-oxovitamin d3, or its hydroxyl-protecting derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5622763A true JPS5622763A (en) 1981-03-03
JPS6258351B2 JPS6258351B2 (en) 1987-12-05

Family

ID=14211067

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9810679A Granted JPS5622763A (en) 1979-02-15 1979-08-02 25-hydroxy-24-oxovitamin d3, or its hydroxyl-protecting derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5622763A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5661351A (en) * 1979-10-26 1981-05-26 Teijin Ltd 1alpha,25-dihydroxy-24-oxocholecalciferols and their preparation
JPS60172960A (en) * 1984-02-17 1985-09-06 Chugai Pharmaceut Co Ltd Novel vitamin d3 derivative
JPS63288811A (en) * 1987-05-22 1988-11-25 Plus Seiki Kk Continuous pitch carrying device

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01114560U (en) * 1988-01-22 1989-08-01

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5661351A (en) * 1979-10-26 1981-05-26 Teijin Ltd 1alpha,25-dihydroxy-24-oxocholecalciferols and their preparation
JPS6258352B2 (en) * 1979-10-26 1987-12-05 Teijin Ltd
JPS60172960A (en) * 1984-02-17 1985-09-06 Chugai Pharmaceut Co Ltd Novel vitamin d3 derivative
JPH0419990B2 (en) * 1984-02-17 1992-03-31 Chugai Pharmaceutical Co Ltd
JPS63288811A (en) * 1987-05-22 1988-11-25 Plus Seiki Kk Continuous pitch carrying device

Also Published As

Publication number Publication date
JPS6258351B2 (en) 1987-12-05

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