JPS5572178A - Preparation of morpholinecarbonyl chloride - Google Patents
Preparation of morpholinecarbonyl chlorideInfo
- Publication number
- JPS5572178A JPS5572178A JP14352778A JP14352778A JPS5572178A JP S5572178 A JPS5572178 A JP S5572178A JP 14352778 A JP14352778 A JP 14352778A JP 14352778 A JP14352778 A JP 14352778A JP S5572178 A JPS5572178 A JP S5572178A
- Authority
- JP
- Japan
- Prior art keywords
- morpholine hydrochloride
- phosgene
- prepared
- liquid medium
- inert liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To prepare the title compound in high purity and yield, with simple procedure, by reacting a morpholine hydrochloride with phosgene in an inert liquid medium.
CONSTITUTION: 4-Morpholinecarbonyl chloride is prepared by reacting morpholine hydrochloride with phosgene in an inert liquid medium such as toluene and xylene, at 50W150°C, pref. 60W120°C. The morpholine hydrochloride is prepared by dissolving 1 part by weight of morpholine in ≥4 parts of an inert liquid medium, and introducing a slightly excessive HCl into the solution under agitation. The morpholine hydrochloride thus prepared can be used to the above reaction without separation. Drawbacks of the conventional preparation process (low-temperature reaction, low yield, use of phosgene in large excess, etc.) are improved.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14352778A JPS5572178A (en) | 1978-11-22 | 1978-11-22 | Preparation of morpholinecarbonyl chloride |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14352778A JPS5572178A (en) | 1978-11-22 | 1978-11-22 | Preparation of morpholinecarbonyl chloride |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5572178A true JPS5572178A (en) | 1980-05-30 |
Family
ID=15340806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14352778A Pending JPS5572178A (en) | 1978-11-22 | 1978-11-22 | Preparation of morpholinecarbonyl chloride |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5572178A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104341374A (en) * | 2014-11-11 | 2015-02-11 | 联化科技(德州)有限公司 | Preparation method for morpholine carbonyl chloride compound |
-
1978
- 1978-11-22 JP JP14352778A patent/JPS5572178A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104341374A (en) * | 2014-11-11 | 2015-02-11 | 联化科技(德州)有限公司 | Preparation method for morpholine carbonyl chloride compound |
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