JPS5545666A - Heterocyclic derivative and its acid adduct - Google Patents

Heterocyclic derivative and its acid adduct

Info

Publication number
JPS5545666A
JPS5545666A JP12004178A JP12004178A JPS5545666A JP S5545666 A JPS5545666 A JP S5545666A JP 12004178 A JP12004178 A JP 12004178A JP 12004178 A JP12004178 A JP 12004178A JP S5545666 A JPS5545666 A JP S5545666A
Authority
JP
Japan
Prior art keywords
formula
compound
acid adduct
heterocyclic derivative
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12004178A
Other languages
Japanese (ja)
Inventor
Tomohiko Munakata
Sumi Saeki
Kazuhiro Goto
Kiyoteru Ikegami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP12004178A priority Critical patent/JPS5545666A/en
Priority to CA336,456A priority patent/CA1131226A/en
Priority to GB7933124A priority patent/GB2031426B/en
Priority to SE7908024A priority patent/SE7908024L/en
Priority to DE19792939224 priority patent/DE2939224A1/en
Priority to CH869279A priority patent/CH644384A5/en
Priority to IT7950378A priority patent/IT1167053B/en
Priority to US06/079,723 priority patent/US4244952A/en
Priority to FR7924278A priority patent/FR2437410A1/en
Priority to BE0/197382A priority patent/BE879077A/en
Publication of JPS5545666A publication Critical patent/JPS5545666A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Abstract

NEW MATERIAL:Heterocyclic derivatives of formula I (R1, R2 are H, lower alkyl, aryl, or incorporate to form benzene ring, where the aryl and benzene ring may be substituted with at least one of lower alkyl, lower alkoxy, halogen, nitro, etc. in any position) or their salts.
EXAMPLE: Pyrido[3',4':5,4]thiazolo[3,2-a]benzimidazole.
USE: Drugs or their intermediate as anti-inflammatory, antirheumatic, immunosuppresive, antibacterial, analgesic or antitumorigenic.
PREPARATION: The dehydrogenation of a novel compound of formula II gives the objective compound of formula I. The compound of formula II is obtained by de- ethoxycarbonylation of a compound of formula V, the product of reaction between a compound of formula III and a compound of formula IV (R1', R2' are H, lower alkyls, aryls; X is halogen).
COPYRIGHT: (C)1980,JPO&Japio
JP12004178A 1978-09-28 1978-09-28 Heterocyclic derivative and its acid adduct Pending JPS5545666A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP12004178A JPS5545666A (en) 1978-09-28 1978-09-28 Heterocyclic derivative and its acid adduct
CA336,456A CA1131226A (en) 1978-09-28 1979-09-25 Heterocyclic compounds
GB7933124A GB2031426B (en) 1978-09-28 1979-09-25 Imidazo(2',1':2,3)thiazolo(5,4-c)pyridines and related compounds
SE7908024A SE7908024L (en) 1978-09-28 1979-09-27 Heterocyclic Associations
DE19792939224 DE2939224A1 (en) 1978-09-28 1979-09-27 IMIDAZO ANGLE CLAMP ON 2 ', 1' TO 2.3 ANGLE CLAMP TO THIAZOLO ANGLE CLAMP TO 5.4-C ANGLE CLAMP TO PYRIDINE
CH869279A CH644384A5 (en) 1978-09-28 1979-09-27 IMIDAZO (2 ', 1': 2.3) THIAZOLO (5.4-C) PYRIDINE.
IT7950378A IT1167053B (en) 1978-09-28 1979-09-27 THERAPEUTICALLY PREGEABLE HETEROCYCLIC COMPOUNDS IN THE TREATMENT OF AUTOIMMUNE DISEASES
US06/079,723 US4244952A (en) 1978-09-28 1979-09-28 Imidazo[2',1':2,3]-thiazolo[5,4-c]pyridines and composition thereof for treating immune diseases
FR7924278A FR2437410A1 (en) 1978-09-28 1979-09-28 NOVEL CHEMICAL COMPOUNDS ACTING ON IMMUNOLOGICAL CONDITIONS
BE0/197382A BE879077A (en) 1978-09-28 1979-09-28 NOVEL CHEMICAL COMPOUNDS ACTING ON IMMUNOLOGICAL CONDITIONS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12004178A JPS5545666A (en) 1978-09-28 1978-09-28 Heterocyclic derivative and its acid adduct

Publications (1)

Publication Number Publication Date
JPS5545666A true JPS5545666A (en) 1980-03-31

Family

ID=14776427

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12004178A Pending JPS5545666A (en) 1978-09-28 1978-09-28 Heterocyclic derivative and its acid adduct

Country Status (2)

Country Link
JP (1) JPS5545666A (en)
BE (1) BE879077A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170025809A (en) * 2015-08-31 2017-03-08 희성소재 (주) Hetero-cyclic compound and organic light emitting device using the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170025809A (en) * 2015-08-31 2017-03-08 희성소재 (주) Hetero-cyclic compound and organic light emitting device using the same

Also Published As

Publication number Publication date
BE879077A (en) 1980-01-16

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