JPS5519214A - 2-acyl-6-aminomethylphenol derivative and its preparation - Google Patents

2-acyl-6-aminomethylphenol derivative and its preparation

Info

Publication number
JPS5519214A
JPS5519214A JP9103178A JP9103178A JPS5519214A JP S5519214 A JPS5519214 A JP S5519214A JP 9103178 A JP9103178 A JP 9103178A JP 9103178 A JP9103178 A JP 9103178A JP S5519214 A JPS5519214 A JP S5519214A
Authority
JP
Japan
Prior art keywords
alkyl
acyl
aminomethylphenol
preparation
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9103178A
Other languages
English (en)
Other versions
JPS623145B2 (ja
Inventor
Hiroyuki Ito
Yoshitoshi Keno
Takao Tokuhiro
Sadahiko Iguchi
Masaki Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP9103178A priority Critical patent/JPS5519214A/ja
Priority to GB7923837A priority patent/GB2026480B/en
Priority to DE19792929760 priority patent/DE2929760A1/de
Priority to IT49843/79A priority patent/IT1118899B/it
Priority to US06/060,113 priority patent/US4245099A/en
Priority to CH694479A priority patent/CH641148A5/de
Priority to FR7919332A priority patent/FR2433506A1/fr
Publication of JPS5519214A publication Critical patent/JPS5519214A/ja
Publication of JPS623145B2 publication Critical patent/JPS623145B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/825Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
JP9103178A 1978-07-27 1978-07-27 2-acyl-6-aminomethylphenol derivative and its preparation Granted JPS5519214A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP9103178A JPS5519214A (en) 1978-07-27 1978-07-27 2-acyl-6-aminomethylphenol derivative and its preparation
GB7923837A GB2026480B (en) 1978-07-27 1979-07-09 2 - acyl - 6 - aminomethylphenol derivative and process for preparing the same
DE19792929760 DE2929760A1 (de) 1978-07-27 1979-07-23 2-acyl-6-aminomethylphenolderivate, verfahren zu ihrer herstellung und sie enthaltende derivate
IT49843/79A IT1118899B (it) 1978-07-27 1979-07-24 Derivati di 2-acil-6 amminometilfenolo e procedimento per prepararli
US06/060,113 US4245099A (en) 1978-07-27 1979-07-24 2-Acyl-6-aminomethylphenol derivatives
CH694479A CH641148A5 (de) 1978-07-27 1979-07-26 2-acyl-6-aminomethylphenol-derivate und verfahren zu ihrer herstellung.
FR7919332A FR2433506A1 (fr) 1978-07-27 1979-07-26 Derives de 2-acyl-6-aminomethylphenol et procede permettant leur preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9103178A JPS5519214A (en) 1978-07-27 1978-07-27 2-acyl-6-aminomethylphenol derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5519214A true JPS5519214A (en) 1980-02-09
JPS623145B2 JPS623145B2 (ja) 1987-01-23

Family

ID=14015141

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9103178A Granted JPS5519214A (en) 1978-07-27 1978-07-27 2-acyl-6-aminomethylphenol derivative and its preparation

Country Status (7)

Country Link
US (1) US4245099A (ja)
JP (1) JPS5519214A (ja)
CH (1) CH641148A5 (ja)
DE (1) DE2929760A1 (ja)
FR (1) FR2433506A1 (ja)
GB (1) GB2026480B (ja)
IT (1) IT1118899B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0065874A1 (en) * 1981-05-22 1982-12-01 Ono Pharmaceutical Co., Ltd. 2-Aminophenol derivatives, methods for their preparation and composition containing the same
US4749804A (en) * 1981-12-11 1988-06-07 Syntex (U.S.A.) Inc. Preparation of stereoisomers of ketals
US5210258A (en) * 1981-12-11 1993-05-11 Syntex Pharmaceuticals International Ltd. Optically active alpha-naththylalkyl ketones
FI82680C (fi) * 1981-12-11 1991-04-10 Syntex Pharma Int Framstaellning av - arylalkansyror.
US5177111A (en) * 1989-12-14 1993-01-05 Hoechst-Roussel Pharmaceuticals Inc. Alkylamino- and alkylamino alkyl diarylketones and pharmaceutical compositions thereof
US5006563A (en) * 1989-12-14 1991-04-09 Hoechst-Roussel Pharmaceuticals Inc. Alkylamino- and alkylamino alkyl diarylketones
GB9620202D0 (en) * 1996-09-27 1996-11-13 Rhone Poulenc Agriculture New herbicides
CN107007916A (zh) * 2016-02-22 2017-08-04 汤马斯·定华·雷 气管插管导丝及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3809721A (en) * 1970-12-23 1974-05-07 Merck & Co Inc Substituted 2-aminomethyl-4,6-disubstituted phenols
US4069256A (en) * 1975-01-20 1978-01-17 Sterling Drug Inc. Anti-inflammatory phenyl-lower-alkylamines
US4083868A (en) * 1976-08-16 1978-04-11 Abbott Laboratories 2-(α-Amidobenzyl)-5-alkylresorcinols

Also Published As

Publication number Publication date
FR2433506A1 (fr) 1980-03-14
US4245099A (en) 1981-01-13
CH641148A5 (de) 1984-02-15
DE2929760C2 (ja) 1987-05-27
GB2026480B (en) 1982-12-15
JPS623145B2 (ja) 1987-01-23
FR2433506B1 (ja) 1981-11-27
IT7949843A0 (it) 1979-07-24
DE2929760A1 (de) 1980-02-07
IT1118899B (it) 1986-03-03
GB2026480A (en) 1980-02-06

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