JPS55143928A - Preparation of coenzyme q analog compound - Google Patents

Preparation of coenzyme q analog compound

Info

Publication number
JPS55143928A
JPS55143928A JP5241079A JP5241079A JPS55143928A JP S55143928 A JPS55143928 A JP S55143928A JP 5241079 A JP5241079 A JP 5241079A JP 5241079 A JP5241079 A JP 5241079A JP S55143928 A JPS55143928 A JP S55143928A
Authority
JP
Japan
Prior art keywords
formula
layer
compound
catalyst
coenzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5241079A
Other languages
Japanese (ja)
Other versions
JPS625414B2 (en
Inventor
Hirokazu Ryono
Arahiko Eguchi
Fusayoshi Kakizaki
Hirozumi Etou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP5241079A priority Critical patent/JPS55143928A/en
Publication of JPS55143928A publication Critical patent/JPS55143928A/en
Publication of JPS625414B2 publication Critical patent/JPS625414B2/ja
Granted legal-status Critical Current

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  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the title compound, useful as a coenzyme Q in simple procedures, by condensing a hydroquinone derivative with a prenol in the presence of a catalyst in a specific mixed solvent, and by oxidizing the hydrocarbon solvent layer separated from the condensate.
CONSTITUTION: A compound of formula I (R2 is H or alkyl group) is condensed with a compound of formula II or III [R1 is formula V (n is an integer 0W9; A and B are H or may form a direct bond A-B] in the presence of an acid catalyst in a mixture of a hydrocarbon (H) and a hydrophilic solvent (B) which is inert to the catalyst and separates into a layer in contact with H, to obtain the compound of formula VI selectively present in H in high yield. The H layer is then separated from the B layer, and oxidized to give the compound of formula IV simply in high yield. The unreactd raw materials, selectively present in the B layer, can be recovered and reused simply and industrially advantageously.
COPYRIGHT: (C)1980,JPO&Japio
JP5241079A 1979-04-27 1979-04-27 Preparation of coenzyme q analog compound Granted JPS55143928A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5241079A JPS55143928A (en) 1979-04-27 1979-04-27 Preparation of coenzyme q analog compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5241079A JPS55143928A (en) 1979-04-27 1979-04-27 Preparation of coenzyme q analog compound

Publications (2)

Publication Number Publication Date
JPS55143928A true JPS55143928A (en) 1980-11-10
JPS625414B2 JPS625414B2 (en) 1987-02-04

Family

ID=12914007

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5241079A Granted JPS55143928A (en) 1979-04-27 1979-04-27 Preparation of coenzyme q analog compound

Country Status (1)

Country Link
JP (1) JPS55143928A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100351219C (en) * 2004-10-14 2007-11-28 昆明韬辉生物工贸有限责任公司 Grignard reagent coupling process of synthesizing coenzyme Q10
JP2009505969A (en) * 2005-08-10 2009-02-12 ディーエスエム アイピー アセッツ ビー．ブイ． Preparation method of ubihydroquinone and ubiquinone

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100351219C (en) * 2004-10-14 2007-11-28 昆明韬辉生物工贸有限责任公司 Grignard reagent coupling process of synthesizing coenzyme Q10
JP2009505969A (en) * 2005-08-10 2009-02-12 ディーエスエム アイピー アセッツ ビー．ブイ． Preparation method of ubihydroquinone and ubiquinone
KR101366958B1 (en) * 2005-08-10 2014-03-12 디에스엠 아이피 어셋츠 비.브이. Process for the preparation of ubihydroquinones and ubiquinones

Also Published As

Publication number Publication date
JPS625414B2 (en) 1987-02-04

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