JPS55136221A - Antibiotic of nonstimulative or slightly stimulative and nonaccelating or slightly accelating diterpene alcoho and*or derivative as active ingredient - Google Patents

Antibiotic of nonstimulative or slightly stimulative and nonaccelating or slightly accelating diterpene alcoho and*or derivative as active ingredient

Info

Publication number
JPS55136221A
JPS55136221A JP672980A JP672980A JPS55136221A JP S55136221 A JPS55136221 A JP S55136221A JP 672980 A JP672980 A JP 672980A JP 672980 A JP672980 A JP 672980A JP S55136221 A JPS55136221 A JP S55136221A
Authority
JP
Japan
Prior art keywords
slightly
nonstimulative
nonaccelating
accelating
stimulative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP672980A
Other languages
English (en)
Inventor
Hetsukaa Eerihi
Osubuaruto Hansu
Shiyumitsuto Rainaa
Yoozefu Opufuerukuufu Hansu
Zoruku Berunto
Aadorufu Buarutaa
Yusefu Maamuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Original Assignee
Deutsches Krebsforschungszentrum DKFZ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforschungszentrum DKFZ filed Critical Deutsches Krebsforschungszentrum DKFZ
Publication of JPS55136221A publication Critical patent/JPS55136221A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Means For Warming Up And Starting Carburetors (AREA)
  • Buckles (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
JP672980A 1979-01-23 1980-01-23 Antibiotic of nonstimulative or slightly stimulative and nonaccelating or slightly accelating diterpene alcoho and*or derivative as active ingredient Pending JPS55136221A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792902506 DE2902506A1 (de) 1979-01-23 1979-01-23 Verwendung von nicht oder nur gering irritierenden und/oder promovierenden diterpenalkoholen und von derivaten davon als antineoplastische mittel

Publications (1)

Publication Number Publication Date
JPS55136221A true JPS55136221A (en) 1980-10-23

Family

ID=6061217

Family Applications (1)

Application Number Title Priority Date Filing Date
JP672980A Pending JPS55136221A (en) 1979-01-23 1980-01-23 Antibiotic of nonstimulative or slightly stimulative and nonaccelating or slightly accelating diterpene alcoho and*or derivative as active ingredient

Country Status (15)

Country Link
US (1) US4716179A (ja)
EP (1) EP0013983B1 (ja)
JP (1) JPS55136221A (ja)
AT (1) ATE8203T1 (ja)
AU (1) AU529955B2 (ja)
CA (1) CA1160953A (ja)
DD (1) DD150430A5 (ja)
DE (1) DE2902506A1 (ja)
DK (1) DK26180A (ja)
FI (1) FI800171A (ja)
IE (1) IE50419B1 (ja)
MC (1) MC1298A1 (ja)
NO (1) NO800148L (ja)
YU (1) YU17880A (ja)
ZA (1) ZA80403B (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04503360A (ja) * 1989-05-30 1992-06-18 アメリカ合衆国 カプサイシン様応答のための活性の可変スペクトルを有する化合物の新規種類、それらの組成物および用途
JP2014507393A (ja) * 2010-12-22 2014-03-27 レオ・ラボラトリーズ・リミテッド ３−アシル−イノゲノールｉｉ
JP2014507396A (ja) * 2010-12-22 2014-03-27 レオ・ラボラトリーズ・リミテッド イノゲノール−３−アシラートｉ
JP2015521639A (ja) * 2012-06-26 2015-07-30 レオ・ラボラトリーズ・リミテッドＬｅｏ Ｌａｂｏｒａｔｏｒｉｅｓ Ｌｉｍｉｔｅｄ ３−ｏ−ヘテロアリール−インゲノール

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962498A (en) * 1986-06-11 1999-10-05 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity
US5716968A (en) * 1986-06-11 1998-02-10 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. H.
US5750568A (en) * 1986-06-11 1998-05-12 Procyon Pharmaceuticals, Inc. Protein kinase C Modulators. L.
US6080784A (en) * 1986-06-11 2000-06-27 Procyon Pharmaceuticals, Inc. Protein kinase C modulators N
US6043270A (en) * 1986-06-11 2000-03-28 Procyon Pharmaceuticals, Inc. Protein kinase C modulators V
US5955501A (en) * 1986-06-11 1999-09-21 Procyon Pharmaceuticals, Inc. Protein kinase C modulators O
US5886019A (en) * 1986-06-11 1999-03-23 Procyon Pharmaceuticals, Inc. Protein kinase C modulators. F.
US5891870A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Protein kinase C modulators Q
US5891906A (en) * 1986-06-11 1999-04-06 Procyon Pharmaceuticals, Inc. Polyacetate-derived phorboids having anti-inflammatory and other uses
US4818359A (en) * 1986-08-27 1989-04-04 International Business Machines Corporation Low contamination RF sputter deposition apparatus
US4939149A (en) * 1988-10-24 1990-07-03 The United States Of America As Represented By The Department Of Health And Human Services Resiniferatoxin and analogues thereof to cause sensory afferent C-fiber and thermoregulatory desensitization
DE4005159A1 (de) * 1990-02-17 1991-08-22 Merck Patent Gmbh Diterpene mit immunmodulatorischer wirkung
WO1992017064A2 (en) * 1991-04-08 1992-10-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inhibitors of protein kinase c function
US5405875A (en) * 1991-04-08 1995-04-11 The United States Of America As Represented By The Department Of Health And Human Services Method of inhibiting neoplasia and tumor promotion
AUPO864097A0 (en) 1997-08-19 1997-09-11 Peplin Pty Ltd Anti-cancer compounds
KR100336982B1 (ko) * 1998-12-31 2002-05-17 성재갑 피부 미백용 조성물
AUPQ801700A0 (en) 2000-06-07 2000-06-29 Peplin Research Pty Ltd Enzyme and viral activation
AUPQ923100A0 (en) 2000-08-07 2000-08-31 Peplin Research Pty Ltd Treatment of prostate cancer
GB0126000D0 (en) * 2001-10-30 2001-12-19 Univ Dundee Use of 4ñ Phorbol
DE10233737A1 (de) * 2002-07-24 2004-02-05 Morphochem Aktiengesellschaft für kombinatorische Chemie Verwendung von Modulatoren des Signaltransduktionswegs über die Proteinkinase Fyn zur Behandlung von Tumorerkrankungen
US7208183B2 (en) * 2002-10-05 2007-04-24 Bobrowski Paul J Methods and preparations of the latex from the croton species
NZ554710A (en) 2004-12-13 2010-03-26 Peplin Research Pty Ltd Treatment of solid cancers with angeloyl substituted ingenanes
BRPI0618926A2 (pt) * 2005-11-25 2011-09-13 Peplin Research Pty Ltd uso de um composto de ingenol ou um sal farmaceuticamente aceitável do mesmo
CN107164422B (zh) * 2016-03-08 2021-01-22 复旦大学 续随子二萜醇衍生物的转化方法及其在制备抗肿瘤药物中的用途
CN107164421B (zh) * 2016-03-08 2021-01-26 复旦大学 羟基化续随子二萜烷型衍生物的转化方法及其在制备抗肿瘤药物中的用途
US10722484B2 (en) 2016-03-09 2020-07-28 K-Gen, Inc. Methods of cancer treatment

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04503360A (ja) * 1989-05-30 1992-06-18 アメリカ合衆国 カプサイシン様応答のための活性の可変スペクトルを有する化合物の新規種類、それらの組成物および用途
JP2694479B2 (ja) * 1989-05-30 1997-12-24 アメリカ合衆国 カプサイシン様応答のための活性の可変スペクトルを有する化合物の新規種類、それらの組成物および用途
JP2014507393A (ja) * 2010-12-22 2014-03-27 レオ・ラボラトリーズ・リミテッド ３−アシル−イノゲノールｉｉ
JP2014507396A (ja) * 2010-12-22 2014-03-27 レオ・ラボラトリーズ・リミテッド イノゲノール−３−アシラートｉ
JP2015521639A (ja) * 2012-06-26 2015-07-30 レオ・ラボラトリーズ・リミテッドＬｅｏ Ｌａｂｏｒａｔｏｒｉｅｓ Ｌｉｍｉｔｅｄ ３−ｏ−ヘテロアリール−インゲノール

Also Published As

Publication number Publication date
US4716179A (en) 1987-12-29
FI800171A (fi) 1980-07-24
AU529955B2 (en) 1983-06-30
EP0013983A3 (en) 1981-03-25
ZA80403B (en) 1981-01-28
EP0013983A2 (de) 1980-08-06
DK26180A (da) 1980-07-24
DD150430A5 (de) 1981-09-02
EP0013983B1 (de) 1984-07-04
AU5486080A (en) 1980-07-31
IE50419B1 (en) 1986-04-16
DE2902506A1 (de) 1980-07-24
ATE8203T1 (de) 1984-07-15
NO800148L (no) 1980-07-24
YU17880A (en) 1983-01-21
MC1298A1 (fr) 1980-10-03
CA1160953A (en) 1984-01-24
IE800132L (en) 1980-07-23

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