JPS55122774A - Production of alpha-halogen substituted-gamma-butyrolactones - Google Patents

Production of alpha-halogen substituted-gamma-butyrolactones

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Publication number
JPS55122774A
JPS55122774A JP3028579A JP3028579A JPS55122774A JP S55122774 A JPS55122774 A JP S55122774A JP 3028579 A JP3028579 A JP 3028579A JP 3028579 A JP3028579 A JP 3028579A JP S55122774 A JPS55122774 A JP S55122774A
Authority
JP
Japan
Prior art keywords
halogen
alkyl
formula
halogenocarboxylic
butyrolactones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3028579A
Other languages
Japanese (ja)
Other versions
JPS5931505B2 (en
Inventor
Yoichiro Nagai
Hideyuki Matsumoto
Taichi Nakano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP3028579A priority Critical patent/JPS5931505B2/en
Publication of JPS55122774A publication Critical patent/JPS55122774A/en
Publication of JPS5931505B2 publication Critical patent/JPS5931505B2/en
Expired legal-status Critical Current

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Abstract

PURPOSE: An α-halogenocarboxylic trialkylsilyl ester is used as a starting material to produce title compound useful as intermediate of amino acid, medicine, surfactant and others without restriction by olefins employed.
CONSTITUTION: The reaction between an olefin of formula I (R1WR3 are H, halogen, cyano, alkyl, alkenyl, aryl, R1, R2, R3 combine together to form at least 3C organic cyclic group) and an α-halogenocarboxylic trialkylsilyl ester of formula II (R4 is H, halogen, 1W4C alkyl; X is halogen; R5 is 1W4C alkyl) is carried out in the presence of a catalyst of ruthenium or rhodium complex having trivalent organophosphorus compound as a ligand to produce the objective compound of formula III. These compounds are important as synthetic intermediate of unsaturated lactones with carcinostatic activity such as Δα,β-butenolide or α-methylene-γ-butyrolactone.
COPYRIGHT: (C)1980,JPO&Japio
JP3028579A 1979-03-15 1979-03-15 Method for producing α-halogen-substituted-γ-butyrolactones Expired JPS5931505B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3028579A JPS5931505B2 (en) 1979-03-15 1979-03-15 Method for producing α-halogen-substituted-γ-butyrolactones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3028579A JPS5931505B2 (en) 1979-03-15 1979-03-15 Method for producing α-halogen-substituted-γ-butyrolactones

Publications (2)

Publication Number Publication Date
JPS55122774A true JPS55122774A (en) 1980-09-20
JPS5931505B2 JPS5931505B2 (en) 1984-08-02

Family

ID=12299438

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3028579A Expired JPS5931505B2 (en) 1979-03-15 1979-03-15 Method for producing α-halogen-substituted-γ-butyrolactones

Country Status (1)

Country Link
JP (1) JPS5931505B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61256309A (en) * 1985-05-10 1986-11-13 Omron Tateisi Electronics Co Coupling device between three-dimensional optical waveguide and optical fiber
US4954623A (en) * 1989-03-20 1990-09-04 Eli Lilly And Company Recovery of difluoro sugar

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61256309A (en) * 1985-05-10 1986-11-13 Omron Tateisi Electronics Co Coupling device between three-dimensional optical waveguide and optical fiber
US4954623A (en) * 1989-03-20 1990-09-04 Eli Lilly And Company Recovery of difluoro sugar

Also Published As

Publication number Publication date
JPS5931505B2 (en) 1984-08-02

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