JPS5490196A - Novel 1,n6-etheno-2-iodo-adenosine-3',5'-cyclic phosphoric acid,its salt,and their preparation - Google Patents
Novel 1,n6-etheno-2-iodo-adenosine-3',5'-cyclic phosphoric acid,its salt,and their preparationInfo
- Publication number
- JPS5490196A JPS5490196A JP15654077A JP15654077A JPS5490196A JP S5490196 A JPS5490196 A JP S5490196A JP 15654077 A JP15654077 A JP 15654077A JP 15654077 A JP15654077 A JP 15654077A JP S5490196 A JPS5490196 A JP S5490196A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- salt
- phosphoric acid
- compound
- etheno
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:1,N6-Etheno-2-iodo-adenosine-3',5'-cylic phosphoric acid of formula I: (Z1 is H, alkali metal, or organic ammonium group) or its salt.
USE: Biochemical reagents, e.g. a reagent for measuring phosphodiesterase activity, anticarcinogens, coronary vasodilators, blood platelet agglutination suppressants, diuretics, and antiallergic agants, having fluorescence.
PROCESS: A compound of formula II or its salt is reacted with I2 or an iodide of the formula Z2I (Z2 is H or alkali metal) in an aqueous solution at 5W50°C preferably 15W25°C for 0.5W24hr to give the compound of formula I or its salt. The compound of formula II is obtained by reaction of a compound of formula A: (X is 3-β-D-ribofuranosyl-3',5'-cyclic phosphoric acid) with chloroacetaldehyde, followed by hydrolysis and cyclization.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15654077A JPS5490196A (en) | 1977-12-27 | 1977-12-27 | Novel 1,n6-etheno-2-iodo-adenosine-3',5'-cyclic phosphoric acid,its salt,and their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15654077A JPS5490196A (en) | 1977-12-27 | 1977-12-27 | Novel 1,n6-etheno-2-iodo-adenosine-3',5'-cyclic phosphoric acid,its salt,and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5490196A true JPS5490196A (en) | 1979-07-17 |
Family
ID=15630019
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15654077A Pending JPS5490196A (en) | 1977-12-27 | 1977-12-27 | Novel 1,n6-etheno-2-iodo-adenosine-3',5'-cyclic phosphoric acid,its salt,and their preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5490196A (en) |
-
1977
- 1977-12-27 JP JP15654077A patent/JPS5490196A/en active Pending
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