JPS5448770A - 5-alkoxypicolinic acid ester, its preparation and hypotensive agent containing the same - Google Patents

5-alkoxypicolinic acid ester, its preparation and hypotensive agent containing the same

Info

Publication number
JPS5448770A
JPS5448770A JP11501377A JP11501377A JPS5448770A JP S5448770 A JPS5448770 A JP S5448770A JP 11501377 A JP11501377 A JP 11501377A JP 11501377 A JP11501377 A JP 11501377A JP S5448770 A JPS5448770 A JP S5448770A
Authority
JP
Japan
Prior art keywords
compound
acid ester
preparation
same
hypotensive agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11501377A
Other languages
Japanese (ja)
Other versions
JPS6134422B2 (en
Inventor
Takemi Koeda
Takashi Tsuruoka
Uichi Shibata
Hiroyasu Asaoka
Mitsugi Hachisu
Osamu Ito
Taiji Sekizawa
Shigeharu Inoue
Taro Niida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP11501377A priority Critical patent/JPS5448770A/en
Publication of JPS5448770A publication Critical patent/JPS5448770A/en
Publication of JPS6134422B2 publication Critical patent/JPS6134422B2/ja
Granted legal-status Critical Current

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Landscapes

  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:5-Alkoxy-picolinic acid ester I [R1 is 1-6C alkyl; R2 is phenhl, substituted phenyl, phthalidyl, alkoxyaikyl, alkoxyalkoxyalkyl, II (R3 is H, methyl; R4 is 1-6C alkyl, phenyl, substituted phenyl, 1-4C alkoxy, aralkyl)].
EXAMPLE: 5-n-Butyloxypicolinic acid pivaroyloxymethyl ester.
USE: Hypotensive agent for oral administration having reduced toxicity.
PROCESS: The compound I can be prepared either by reacting a compound III (M is H, metal atom) with a compound IV (X is haogen) in the presence of a base, or by reacting the compound III with a compound V (R5-7 are H, lower alkyl, lower alkoxyhalogen) in the presence of a condensing agent
COPYRIGHT: (C)1979,JPO&Japio
JP11501377A 1977-09-24 1977-09-24 5-alkoxypicolinic acid ester, its preparation and hypotensive agent containing the same Granted JPS5448770A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11501377A JPS5448770A (en) 1977-09-24 1977-09-24 5-alkoxypicolinic acid ester, its preparation and hypotensive agent containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11501377A JPS5448770A (en) 1977-09-24 1977-09-24 5-alkoxypicolinic acid ester, its preparation and hypotensive agent containing the same

Publications (2)

Publication Number Publication Date
JPS5448770A true JPS5448770A (en) 1979-04-17
JPS6134422B2 JPS6134422B2 (en) 1986-08-07

Family

ID=14652096

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11501377A Granted JPS5448770A (en) 1977-09-24 1977-09-24 5-alkoxypicolinic acid ester, its preparation and hypotensive agent containing the same

Country Status (1)

Country Link
JP (1) JPS5448770A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53149121U (en) * 1978-03-15 1978-11-24

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53149121U (en) * 1978-03-15 1978-11-24
JPS5537705Y2 (en) * 1978-03-15 1980-09-04

Also Published As

Publication number Publication date
JPS6134422B2 (en) 1986-08-07

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