JPS5438098B2 - - Google Patents

Info

Publication number
JPS5438098B2
JPS5438098B2 JP12905974A JP12905974A JPS5438098B2 JP S5438098 B2 JPS5438098 B2 JP S5438098B2 JP 12905974 A JP12905974 A JP 12905974A JP 12905974 A JP12905974 A JP 12905974A JP S5438098 B2 JPS5438098 B2 JP S5438098B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP12905974A
Other languages
Japanese (ja)
Other versions
JPS5077360A (cg-RX-API-DMAC7.html
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5077360A publication Critical patent/JPS5077360A/ja
Publication of JPS5438098B2 publication Critical patent/JPS5438098B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
JP12905974A 1973-11-12 1974-11-11 Expired JPS5438098B2 (cg-RX-API-DMAC7.html)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US415186A US3887545A (en) 1973-11-12 1973-11-12 Synthesis of 1{60 -hydroxylated cholesterol derivatives

Publications (2)

Publication Number Publication Date
JPS5077360A JPS5077360A (cg-RX-API-DMAC7.html) 1975-06-24
JPS5438098B2 true JPS5438098B2 (cg-RX-API-DMAC7.html) 1979-11-19

Family

ID=23644712

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12905974A Expired JPS5438098B2 (cg-RX-API-DMAC7.html) 1973-11-12 1974-11-11

Country Status (9)

Country Link
US (1) US3887545A (cg-RX-API-DMAC7.html)
JP (1) JPS5438098B2 (cg-RX-API-DMAC7.html)
AT (1) AT342793B (cg-RX-API-DMAC7.html)
BE (1) BE821983A (cg-RX-API-DMAC7.html)
CH (1) CH599247A5 (cg-RX-API-DMAC7.html)
DE (1) DE2453648C3 (cg-RX-API-DMAC7.html)
FR (1) FR2250764B1 (cg-RX-API-DMAC7.html)
GB (1) GB1443680A (cg-RX-API-DMAC7.html)
NL (1) NL7414675A (cg-RX-API-DMAC7.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4264512A (en) * 1975-09-29 1981-04-28 The Regents Of The University Of California 3-Deoxy-1α-hydroxy- and 3-deoxy-1α,25-dihydroxycholecalciferol and processes for the preparation thereof
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 1α―ヒドロキシビタミンD類軟カプセルの製造方法
US4098801A (en) * 1977-01-26 1978-07-04 Hoffmann-La Roche Inc. Synthesis of 1α-hydroxylated derivatives of cholesterol
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
LU80545A1 (de) * 1978-11-17 1980-06-05 Hoffmann La Roche Verfahren zur herstellung von 1a,3s-dihydroxy->5-steroiden
US4217279A (en) * 1978-12-18 1980-08-12 Kaiser Emil T Synthesis of steroids
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
IL130249A0 (en) 1996-12-20 2000-06-01 Novo Nordisk As Meiosis regulating compounds
BR0010197A (pt) * 1999-04-30 2002-07-16 Arch Dev Corp Derivados de esteróides
WO2002062302A2 (en) * 2001-02-08 2002-08-15 The University Of Chicago Steroidal derivatives
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
CA2482195A1 (en) * 2002-04-12 2003-10-23 The University Of Chicago Farnesoid x-activated receptor agonists
US7897588B2 (en) * 2002-08-29 2011-03-01 The Regents Of The University Of California Agents and methods for enhancing bone formation
US9532994B2 (en) * 2003-08-29 2017-01-03 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
EP1877663B1 (de) * 2005-04-23 2009-01-28 ixetic MAC GmbH Axialkolbenmaschine
JP2009512422A (ja) * 2005-09-02 2009-03-26 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 骨形成及び抗脂肪細胞形成オキシステロール類
WO2007098281A2 (en) * 2006-02-27 2007-08-30 Regents Of The University Of California Oxysterol compounds and the hedgehog pathway
WO2008011071A2 (en) * 2006-07-19 2008-01-24 The Regents Of The University Of California Interactions of hedgehog and liver x receptor signaling pathways
EP2111225A4 (en) 2006-12-19 2010-02-10 Univ California INHIBITION OF PPAR GAMMA EXPRESSION BY SPECIFIC OSTEOGENIC OXYSTEROLE
EP2146724A2 (en) * 2007-03-16 2010-01-27 The Regent of the University of California Role of hedgehog signaling in atherosclerosis and cardiovascular disease
CN101951915A (zh) * 2007-12-03 2011-01-19 加利福尼亚大学董事会 用于刺猬蛋白信号、骨诱导、抗脂肪形成和wnt信号的激活的氧固醇
CN102482315A (zh) * 2009-07-29 2012-05-30 芝加哥大学 肝x受体激动剂
US9717742B2 (en) 2012-05-07 2017-08-01 The Regents Of The University Of California Oxysterol analogue OXY133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis
JP2016517888A (ja) 2013-05-02 2016-06-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 骨選択的骨形成のオキシステロール骨標的薬剤
CN114315947B (zh) * 2021-11-17 2023-10-03 王涛 一种由22-甾醇作为原料合成胆固醇和25-羟基胆固醇的新方法
WO2023143400A1 (zh) * 2022-01-28 2023-08-03 珂阑(上海)医药科技有限公司 甾类化合物、其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080937A (en) * 1960-11-07 1963-03-12 Garbell Res Foundation Combined acoustic wall and exhaust gas deflector in operation of jet engines
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol

Also Published As

Publication number Publication date
FR2250764B1 (cg-RX-API-DMAC7.html) 1979-08-03
DE2453648B2 (de) 1980-06-26
BE821983A (fr) 1975-05-09
JPS5077360A (cg-RX-API-DMAC7.html) 1975-06-24
CH599247A5 (cg-RX-API-DMAC7.html) 1978-05-31
DE2453648C3 (de) 1981-08-06
AT342793B (de) 1978-04-25
US3887545A (en) 1975-06-03
NL7414675A (nl) 1975-05-14
GB1443680A (en) 1976-07-21
ATA899274A (de) 1977-08-15
FR2250764A1 (cg-RX-API-DMAC7.html) 1975-06-06
DE2453648A1 (de) 1975-05-15

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