JPS54135793A - Novel cephalosporin derived from 33substitutedd77*22*22aminoo44thiazolyl**22*carboxymethoxy imino*acetoamide* cephalosporanic acid*its manufacture and use as drug and pharmaceutical composition contai - Google Patents

Novel cephalosporin derived from 33substitutedd77*22*22aminoo44thiazolyl**22*carboxymethoxy imino*acetoamide* cephalosporanic acid*its manufacture and use as drug and pharmaceutical composition contai

Info

Publication number
JPS54135793A
JPS54135793A JP4113879A JP4113879A JPS54135793A JP S54135793 A JPS54135793 A JP S54135793A JP 4113879 A JP4113879 A JP 4113879A JP 4113879 A JP4113879 A JP 4113879A JP S54135793 A JPS54135793 A JP S54135793A
Authority
JP
Japan
Prior art keywords
acetoamide
carboxymethoxy
imino
drug
derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4113879A
Other languages
English (en)
Other versions
JPS6360758B2 (ja
Inventor
Eemu Rune
Riyutsutsu Andore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS54135793A publication Critical patent/JPS54135793A/ja
Publication of JPS6360758B2 publication Critical patent/JPS6360758B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP4113879A 1978-04-07 1979-04-06 Novel cephalosporin derived from 33substitutedd77*22*22aminoo44thiazolyl**22*carboxymethoxy imino*acetoamide* cephalosporanic acid*its manufacture and use as drug and pharmaceutical composition contai Granted JPS54135793A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7810387A FR2421907A1 (fr) 1978-04-07 1978-04-07 Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
JPS54135793A true JPS54135793A (en) 1979-10-22
JPS6360758B2 JPS6360758B2 (ja) 1988-11-25

Family

ID=9206849

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4113879A Granted JPS54135793A (en) 1978-04-07 1979-04-06 Novel cephalosporin derived from 33substitutedd77*22*22aminoo44thiazolyl**22*carboxymethoxy imino*acetoamide* cephalosporanic acid*its manufacture and use as drug and pharmaceutical composition contai

Country Status (11)

Country Link
US (1) US4287193A (ja)
JP (1) JPS54135793A (ja)
AT (1) AT365194B (ja)
BE (1) BE875379A (ja)
CH (1) CH639388A5 (ja)
DE (1) DE2914060A1 (ja)
ES (2) ES479273A1 (ja)
FR (1) FR2421907A1 (ja)
GB (1) GB2021561B (ja)
IT (1) IT1162463B (ja)
NL (1) NL7902784A (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535096A (en) * 1978-09-04 1980-03-11 Fujisawa Pharmaceut Co Ltd 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent
JPS5785394A (en) * 1980-09-26 1982-05-28 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation, preventive and remedy for bacterium infectious disease comprising it
JPS6263578A (ja) * 1978-07-31 1987-03-20 Fujisawa Pharmaceut Co Ltd アミノチアゾリル酢酸誘導体

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2462439A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau procede de preparation de produits derives de l'acide 7-/(2-aryl) 2-hydroxyimino acetamido/cephalosporanique
US4507293A (en) * 1980-09-26 1985-03-26 Fujisawa Pharmaceutical Co., Ltd. Antimicrobial cephem compounds
DE3177090D1 (en) 1980-12-31 1989-09-28 Fujisawa Pharmaceutical Co 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
IE53429B1 (en) * 1981-08-03 1988-11-09 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
GB8410992D0 (en) * 1984-04-30 1984-06-06 Glaxo Group Ltd Process
CA2054126A1 (en) * 1990-10-26 1992-04-27 Michiyuki Sendai Cephem compounds, their production and use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS53137988A (en) * 1977-03-14 1978-12-01 Fujisawa Pharmaceut Co Ltd Cephem and cepham compounds and process for their preparation
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091209A (en) * 1971-05-14 1978-05-23 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl or naphthylacetamido)]cephalosporins having a 2-haloalkylcarbamoyloxymethyl group at the 3-position
US4095021A (en) * 1973-12-21 1978-06-13 Glaxo Laboratories Limited 3-Carbamoyloxymethyl or N-methyl-carbamoyloxymethyl-7-[2-carboxymethoxyimino-2-(fur-2-yl or thien-2-yl)acetamido]ceph-3-em-4-carboxylic acids and derivatives thereof
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
CA1115267A (en) * 1976-08-30 1981-12-29 William J. Gottstein 7-(2-alkyloxyimino-2-furylacetamido)-3-(1- carboxyalkyltetrazolyl-5-thiomethyl)-3-cephem-4- carboxylic acid)
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS53137988A (en) * 1977-03-14 1978-12-01 Fujisawa Pharmaceut Co Ltd Cephem and cepham compounds and process for their preparation
JPS549296A (en) * 1977-04-02 1979-01-24 Hoechst Ag Cephem derivative and its preparation

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6263578A (ja) * 1978-07-31 1987-03-20 Fujisawa Pharmaceut Co Ltd アミノチアゾリル酢酸誘導体
JPH0333154B2 (ja) * 1978-07-31 1991-05-16 Fujisawa Pharmaceutical Co
JPS5535096A (en) * 1978-09-04 1980-03-11 Fujisawa Pharmaceut Co Ltd 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent
JPH0240678B2 (ja) * 1978-09-04 1990-09-12 Fujisawa Pharmaceutical Co
JPS5785394A (en) * 1980-09-26 1982-05-28 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation, preventive and remedy for bacterium infectious disease comprising it
JPH0337557B2 (ja) * 1980-09-26 1991-06-05 Fujisawa Pharmaceutical Co

Also Published As

Publication number Publication date
BE875379A (fr) 1979-10-08
ATA255279A (de) 1981-05-15
JPS6360758B2 (ja) 1988-11-25
GB2021561B (en) 1982-11-17
IT7948631A0 (it) 1979-04-05
CH639388A5 (fr) 1983-11-15
DE2914060A1 (de) 1979-10-18
FR2421907B1 (ja) 1981-07-24
DE2914060C2 (ja) 1991-01-24
ES484074A1 (es) 1980-06-16
IT1162463B (it) 1987-04-01
GB2021561A (en) 1979-12-05
AT365194B (de) 1981-12-28
NL7902784A (nl) 1979-10-09
ES479273A1 (es) 1979-12-01
US4287193A (en) 1981-09-01
FR2421907A1 (fr) 1979-11-02

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