JPS5346941A - Thiaprostagradine - Google Patents

Thiaprostagradine

Info

Publication number
JPS5346941A
JPS5346941A JP12044177A JP12044177A JPS5346941A JP S5346941 A JPS5346941 A JP S5346941A JP 12044177 A JP12044177 A JP 12044177A JP 12044177 A JP12044177 A JP 12044177A JP S5346941 A JPS5346941 A JP S5346941A
Authority
JP
Japan
Prior art keywords
thiaprostagradine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12044177A
Other languages
English (en)
Other versions
JPS6225141B2 (ja
Inventor
Raazuntsu Hansuuetsukaaruto
Orutsu Deiitaa
Baumugarutsu Manfuretsudo
Shiyuriipu Hansuuyoohen
Enenkeru Hansuuyoahimu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of JPS5346941A publication Critical patent/JPS5346941A/ja
Publication of JPS6225141B2 publication Critical patent/JPS6225141B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5407—Acyclic saturated phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP12044177A 1976-10-06 1977-10-05 Thiaprostagradine Granted JPS5346941A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2644972A DE2644972C2 (de) 1976-10-06 1976-10-06 Thiaprostansäurederivate, deren Herstellung und diese Verbindungen enthaltende Mittel

Publications (2)

Publication Number Publication Date
JPS5346941A true JPS5346941A (en) 1978-04-27
JPS6225141B2 JPS6225141B2 (ja) 1987-06-01

Family

ID=5989745

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12044177A Granted JPS5346941A (en) 1976-10-06 1977-10-05 Thiaprostagradine

Country Status (18)

Country Link
US (1) US4309441A (ja)
JP (1) JPS5346941A (ja)
AT (1) AT365170B (ja)
AU (1) AU510216B2 (ja)
BE (1) BE859423A (ja)
CA (1) CA1120927A (ja)
CH (3) CH630072A5 (ja)
DE (1) DE2644972C2 (ja)
ES (2) ES462966A1 (ja)
FR (1) FR2367061A1 (ja)
GB (1) GB1549496A (ja)
HU (1) HU178640B (ja)
IL (1) IL53050A (ja)
IT (1) IT1090237B (ja)
NL (1) NL7710931A (ja)
PT (1) PT67086B (ja)
SE (1) SE427656B (ja)
ZA (1) ZA775985B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60161967A (ja) * 1984-01-18 1985-08-23 メルク・パテント・ゲゼルシャフト・ミツト・ベシュレンクテル・ハフツング イオウ含有６‐ケトプロスタクランジン化合物

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5913723A (ja) * 1982-07-14 1984-01-24 メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 細胞保護作用を有する医薬及び１３−チア−プロスタグランジン誘導体の使用
EP0173754B1 (en) * 1984-03-05 1989-04-26 Teijin Limited 7-thiaprostaglandin e 1?'s and process for their preparation
JPS63283835A (ja) * 1987-05-13 1988-11-21 Yaskawa Electric Mfg Co Ltd リニア移動装置
CA2276666A1 (en) 1997-03-07 1998-09-11 Alcon Laboratories, Inc. 13-thia prostaglandins for use in glaucoma therapy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH613189A5 (ja) * 1972-11-17 1979-09-14 Merck Patent Gmbh
DE2256537A1 (de) * 1972-11-17 1974-10-10 Merck Patent Gmbh Neue sulfide
US3894062A (en) * 1973-11-23 1975-07-08 Upjohn Co Substituted phenyl and naphthyl esters of PGE{HD 2
US3932486A (en) * 1974-01-08 1976-01-13 The Upjohn Company Substituted tolyl esters of PGA2
US3931285A (en) * 1974-01-08 1976-01-06 The Upjohn Company Substituted tolyl esters of PGE1
DE2422924A1 (de) * 1974-05-11 1975-11-27 Merck Patent Gmbh Thiaprostaglandine
US3998869A (en) * 1974-11-14 1976-12-21 The Upjohn Company Substituted anilide esters of 16-substituted PGE2
US3994956A (en) * 1974-11-14 1976-11-30 The Upjohn Company Substituted anilide esters of 16-phenoxy and 17-phenyl PGE2 type compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60161967A (ja) * 1984-01-18 1985-08-23 メルク・パテント・ゲゼルシャフト・ミツト・ベシュレンクテル・ハフツング イオウ含有６‐ケトプロスタクランジン化合物

Also Published As

Publication number Publication date
CH630072A5 (de) 1982-05-28
DE2644972A1 (de) 1978-04-13
NL7710931A (nl) 1978-04-10
FR2367061A1 (fr) 1978-05-05
ATA710377A (de) 1981-05-15
ES472511A1 (es) 1979-10-01
AU510216B2 (en) 1980-06-12
HU178640B (en) 1982-06-28
IT1090237B (it) 1985-06-26
AT365170B (de) 1981-12-28
CH639950A5 (de) 1983-12-15
AU2942677A (en) 1979-04-12
PT67086A (en) 1977-10-01
IL53050A0 (en) 1977-12-30
CH640832A5 (de) 1984-01-31
DE2644972C2 (de) 1986-06-19
FR2367061B1 (ja) 1981-02-13
GB1549496A (en) 1979-08-08
CA1120927A (en) 1982-03-30
BE859423A (nl) 1978-04-06
ZA775985B (en) 1978-05-30
PT67086B (en) 1979-02-22
SE7711146L (sv) 1978-04-07
US4309441A (en) 1982-01-05
IL53050A (en) 1981-12-31
SE427656B (sv) 1983-04-25
ES462966A1 (es) 1978-11-01
JPS6225141B2 (ja) 1987-06-01

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