JPS5323961A - Antitumors - Google Patents

Antitumors

Info

Publication number
JPS5323961A
JPS5323961A JP9811376A JP9811376A JPS5323961A JP S5323961 A JPS5323961 A JP S5323961A JP 9811376 A JP9811376 A JP 9811376A JP 9811376 A JP9811376 A JP 9811376A JP S5323961 A JPS5323961 A JP S5323961A
Authority
JP
Japan
Prior art keywords
antitumors
rhodirubin
anthracyclin
glycoside
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9811376A
Other languages
English (en)
Other versions
JPS5438103B2 (ja
Inventor
Hamao Umezawa
Tomio Takeuchi
Masa Hamada
Masaaki Ishizuka
Hiroshi Osanawa
Shunichi Oki
Taiji Inui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP9811376A priority Critical patent/JPS5323961A/ja
Priority to US05/823,052 priority patent/US4127714A/en
Priority to YU1972/77A priority patent/YU39815B/xx
Priority to GB34167/77A priority patent/GB1561619A/en
Priority to CA284,688A priority patent/CA1099652A/en
Priority to FI772442A priority patent/FI59613C/fi
Priority to IE1698/77A priority patent/IE45557B1/en
Priority to DK364677A priority patent/DK146282C/da
Priority to FR7725022A priority patent/FR2362157A1/fr
Priority to LU77970A priority patent/LU77970A1/xx
Priority to AU27937/77A priority patent/AU512279B2/en
Priority to CH1000277A priority patent/CH630958A5/de
Priority to ZA00774967A priority patent/ZA774967B/xx
Priority to NL7709028A priority patent/NL7709028A/xx
Priority to SE7709234A priority patent/SE435069B/xx
Priority to BE180220A priority patent/BE857840A/xx
Publication of JPS5323961A publication Critical patent/JPS5323961A/ja
Priority to US05/898,065 priority patent/US4192915A/en
Publication of JPS5438103B2 publication Critical patent/JPS5438103B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP9811376A 1976-08-16 1976-08-16 Antitumors Granted JPS5323961A (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
JP9811376A JPS5323961A (en) 1976-08-16 1976-08-16 Antitumors
US05/823,052 US4127714A (en) 1976-08-16 1977-08-09 Anthracycline glycosides
YU1972/77A YU39815B (en) 1976-08-16 1977-08-15 Process for producing antitumoral antibiotics rodirubine a and b
GB34167/77A GB1561619A (en) 1976-08-16 1977-08-15 Anthracyclineglycoside antitumor antibiotics
CA284,688A CA1099652A (en) 1976-08-16 1977-08-15 Antitumor antibiotics
FI772442A FI59613C (fi) 1976-08-16 1977-08-15 Foerfarande foer framstaellning av ett tumoerfoerhindrande rhodirubinkomplex och dess komponenter a och b
IE1698/77A IE45557B1 (en) 1976-08-16 1977-08-15 Anthracycline glycoside antitumor antibiotics
LU77970A LU77970A1 (ja) 1976-08-16 1977-08-16
FR7725022A FR2362157A1 (fr) 1976-08-16 1977-08-16 Anthracyclines glycosides nouvelles et leur application pharmacologique
DK364677A DK146282C (da) 1976-08-16 1977-08-16 Fremgangsmaade til fremstilling af anthracyclin-glycosid-antibiotika, kaldet rhodirubin a og b eller salte eller deoxyribonukleinsyrekomplekser deraf
AU27937/77A AU512279B2 (en) 1976-08-16 1977-08-16 Anthracycline gylcoside antitumor antibiotics
CH1000277A CH630958A5 (de) 1976-08-16 1977-08-16 Verfahren zur herstellung von rhodirubin a und rhodirubin b.
ZA00774967A ZA774967B (en) 1976-08-16 1977-08-16 Antitumor antibiotics
NL7709028A NL7709028A (nl) 1976-08-16 1977-08-16 Werkwijze ter bereiding van antracyclineglyco- side anti-tumor antibiotica alsmede preparaten die deze verbindingen als actieve component bevatten.
SE7709234A SE435069B (sv) 1976-08-16 1977-08-16 Forfarande for framstellning av nya antracyklinglykosider, benemnda rhodirubin a och b, genom odling av vissa stammar tillhorande slektet streptomyces
BE180220A BE857840A (fr) 1976-08-16 1977-08-16 Antibiotiques polycycliques
US05/898,065 US4192915A (en) 1976-08-16 1978-04-20 Anthracycline glycosides from streptomyces

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9811376A JPS5323961A (en) 1976-08-16 1976-08-16 Antitumors

Publications (2)

Publication Number Publication Date
JPS5323961A true JPS5323961A (en) 1978-03-06
JPS5438103B2 JPS5438103B2 (ja) 1979-11-19

Family

ID=14211256

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9811376A Granted JPS5323961A (en) 1976-08-16 1976-08-16 Antitumors

Country Status (16)

Country Link
US (1) US4127714A (ja)
JP (1) JPS5323961A (ja)
AU (1) AU512279B2 (ja)
BE (1) BE857840A (ja)
CA (1) CA1099652A (ja)
CH (1) CH630958A5 (ja)
DK (1) DK146282C (ja)
FI (1) FI59613C (ja)
FR (1) FR2362157A1 (ja)
GB (1) GB1561619A (ja)
IE (1) IE45557B1 (ja)
LU (1) LU77970A1 (ja)
NL (1) NL7709028A (ja)
SE (1) SE435069B (ja)
YU (1) YU39815B (ja)
ZA (1) ZA774967B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52136159A (en) * 1976-04-07 1977-11-14 Microbial Chem Res Found Anti/malignanttumor containing the same as active ingredients
US4123608A (en) * 1977-07-18 1978-10-31 Bristol-Myers Company Antibiotic compound
US4277466A (en) * 1978-08-29 1981-07-07 Institut International De Pathologie Cellulaire Et Moleculaire Complexes of DNA and esters derived from daunorubicine, their preparation and use
JPS6023679B2 (ja) * 1979-07-13 1985-06-08 メルシャン株式会社 ロドマイシン群抗生物質とその製造法
PL124284B1 (en) * 1979-10-17 1983-01-31 Politechnika Gdanska Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group
JPS5731696A (en) * 1980-08-01 1982-02-20 Sanraku Inc Anthracycline derivative
CH648327A5 (de) * 1980-10-16 1985-03-15 Hoffmann La Roche Anthracycline.
DE3323025A1 (de) * 1983-06-25 1985-01-10 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
US20050208037A1 (en) * 2003-10-21 2005-09-22 Board Of Regents, The University Of Texas System Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5134915B2 (ja) * 1974-07-27 1976-09-29
US4039736A (en) * 1976-04-15 1977-08-02 Bristol-Myers Company Antibiotic compounds marcellomycin and musettamycin

Also Published As

Publication number Publication date
FI59613B (fi) 1981-05-29
YU39815B (en) 1985-04-30
FI59613C (fi) 1981-09-10
CH630958A5 (de) 1982-07-15
SE435069B (sv) 1984-09-03
SE7709234L (sv) 1978-02-17
BE857840A (fr) 1978-02-16
NL7709028A (nl) 1978-02-20
DK146282C (da) 1984-01-30
IE45557B1 (en) 1982-09-22
DK146282B (da) 1983-08-22
ZA774967B (en) 1978-06-28
FR2362157A1 (fr) 1978-03-17
CA1099652A (en) 1981-04-21
IE45557L (en) 1978-02-16
YU197277A (en) 1982-06-30
FR2362157B1 (ja) 1981-03-20
GB1561619A (en) 1980-02-27
FI772442A (fi) 1978-02-17
JPS5438103B2 (ja) 1979-11-19
AU512279B2 (en) 1980-10-02
AU2793777A (en) 1979-02-22
LU77970A1 (ja) 1978-04-27
US4127714A (en) 1978-11-28
DK364677A (da) 1978-02-17

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