JPS51118777A - Preparation method of new pyrimidine derivatives - Google Patents

Preparation method of new pyrimidine derivatives

Info

Publication number
JPS51118777A
JPS51118777A JP50080752A JP8075275A JPS51118777A JP S51118777 A JPS51118777 A JP S51118777A JP 50080752 A JP50080752 A JP 50080752A JP 8075275 A JP8075275 A JP 8075275A JP S51118777 A JPS51118777 A JP S51118777A
Authority
JP
Japan
Prior art keywords
preparation
pyrimidine derivatives
new pyrimidine
new
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP50080752A
Other languages
English (en)
Japanese (ja)
Inventor
Marii Kuraberii Jiyan
Matsuteioda Jiyorujiyu
Miyuishie Rune
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GEN RUSHIERUSHIYU E APPLIC SHI
JIENERARU DO RUSHIERUSHIYU E DAPURIKASHION SHIANTEIFUIKU SOJIERASU SOC
Original Assignee
GEN RUSHIERUSHIYU E APPLIC SHI
JIENERARU DO RUSHIERUSHIYU E DAPURIKASHION SHIANTEIFUIKU SOJIERASU SOC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEN RUSHIERUSHIYU E APPLIC SHI, JIENERARU DO RUSHIERUSHIYU E DAPURIKASHION SHIANTEIFUIKU SOJIERASU SOC filed Critical GEN RUSHIERUSHIYU E APPLIC SHI
Publication of JPS51118777A publication Critical patent/JPS51118777A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP50080752A 1975-04-10 1975-06-30 Preparation method of new pyrimidine derivatives Pending JPS51118777A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7511154A FR2306697A1 (fr) 1975-04-10 1975-04-10 Nouvelles pyrimidines utilisables comme medicaments antidiabetiques et hypocholesterolemiants

Publications (1)

Publication Number Publication Date
JPS51118777A true JPS51118777A (en) 1976-10-18

Family

ID=9153719

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50080752A Pending JPS51118777A (en) 1975-04-10 1975-06-30 Preparation method of new pyrimidine derivatives

Country Status (12)

Country Link
US (1) US3984411A (show.php)
JP (1) JPS51118777A (show.php)
BE (1) BE829845A (show.php)
CA (1) CA1036597A (show.php)
CH (1) CH603626A5 (show.php)
DE (1) DE2528360A1 (show.php)
ES (1) ES439017A1 (show.php)
FR (1) FR2306697A1 (show.php)
GB (1) GB1502182A (show.php)
IT (1) IT1036400B (show.php)
LU (1) LU72743A1 (show.php)
NL (1) NL7507441A (show.php)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU176972B (hu) * 1977-06-13 1981-06-28 Gyogyszerkutato Intezet Sposob poluchenija novykh proizvodnykh piridazinil-gidrazona
US4648896A (en) * 1982-11-15 1987-03-10 Ciba-Geigy Corporation 2-aryl-4,6-dihalopyrimidines as antidote for protecting cultivated plants from phytotoxic damage caused by herbicides
FI895821A7 (fi) * 1988-12-07 1990-06-08 The Wellcome Foundation Ltd Farmaseuttisesti aktivisia CNS-yhdisteitä
WO1999024422A1 (en) 1997-11-05 1999-05-20 Neurosearch A/S Azaring-ether derivatives and their use as nicotinic ach receptor modulators
CN102558155A (zh) 2003-01-14 2012-07-11 阿伦纳药品公司 作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗
DK1606282T3 (da) * 2003-02-24 2009-03-16 Arena Pharm Inc Phenyl- og pyridylpipereidinye-derivater som modulatorer af glucosemetabolisme
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
CA2441775C (en) * 2003-09-23 2004-09-28 Westport Research Inc. Container for holding a cryogenic fluid
DE602005011279D1 (de) * 2004-06-04 2009-01-08 Arena Pharm Inc Substituierte aryl- und heteroarylderivate als modulatoren des stoffwechsels und für die prophylaxe und behandlung von damit in zusammenhang stehenden erkrankungen
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
RS20080112A (sr) * 2005-09-16 2009-05-06 Arena Pharmaceuticals Inc., Modulatori metabolizma i lečenje poremećaja koji su vezi sa njima
TW200811147A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811140A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
DE602008005319D1 (de) 2007-08-30 2011-04-14 Dow Agrosciences Llc 2-(substituierte phenyl)-6-amino-5-alkoxy-, thioalkoxy- und aminoalkyl-4-pyrimidincarboxylate und ihre verwendung als herbizide
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ， インコーポレイテッド （Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸およびその塩の調製のためのプロセス
EP3323818A1 (en) 2010-09-22 2018-05-23 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
EP4445956A3 (en) 2015-01-06 2024-12-04 Arena Pharmaceuticals, Inc. Compound for use in treating conditions related to the s1p1 receptor
DK3307262T3 (da) 2015-06-15 2021-08-09 Nmd Pharma As Forbindelser til anvendelse ved behandling af neuromuskulære lidelser
EP3310760B8 (en) 2015-06-22 2022-10-19 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in s1p1 receptor-associated disorders
EP3582772A1 (en) 2017-02-16 2019-12-25 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
US11591284B2 (en) 2017-12-14 2023-02-28 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11730714B2 (en) 2017-12-14 2023-08-22 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US12440477B2 (en) 2017-12-14 2025-10-14 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US10385028B2 (en) 2017-12-14 2019-08-20 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
US11147788B2 (en) 2017-12-14 2021-10-19 Nmd Pharma A/S Compounds for the treatment of neuromuscular disorders
KR102859841B1 (ko) 2018-06-06 2025-09-12 아레나 파마슈티칼스, 인크. S1p1 수용체와 관련된 병태의 치료 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
US3261833A (en) * 1964-10-20 1966-07-19 Smith Kline French Lab 2,4-diamino-6-aminoalkoxy pyrimidines
GB1143167A (en) * 1967-01-25 1969-02-19 Ucb Sa Derivatives of pyrimidine

Also Published As

Publication number Publication date
CA1036597A (fr) 1978-08-15
CH603626A5 (show.php) 1978-08-31
ES439017A1 (es) 1977-06-16
FR2306697B1 (show.php) 1979-08-10
NL7507441A (nl) 1976-10-12
BE829845A (fr) 1975-12-04
GB1502182A (en) 1978-02-22
IT1036400B (it) 1979-10-30
DE2528360A1 (de) 1976-10-21
US3984411A (en) 1976-10-05
FR2306697A1 (fr) 1976-11-05
LU72743A1 (show.php) 1975-10-08

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