JPS5087395A - - Google Patents

Info

Publication number
JPS5087395A
JPS5087395A JP49135978A JP13597874A JPS5087395A JP S5087395 A JPS5087395 A JP S5087395A JP 49135978 A JP49135978 A JP 49135978A JP 13597874 A JP13597874 A JP 13597874A JP S5087395 A JPS5087395 A JP S5087395A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP49135978A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5087395A publication Critical patent/JPS5087395A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP49135978A 1973-11-28 1974-11-28 Pending JPS5087395A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41968973A 1973-11-28 1973-11-28
US516090A US3916197A (en) 1973-11-28 1974-10-18 Method and apparatus for classifying biological cells

Publications (1)

Publication Number Publication Date
JPS5087395A true JPS5087395A (ja) 1975-07-14

Family

ID=27024586

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49135978A Pending JPS5087395A (ja) 1973-11-28 1974-11-28

Country Status (5)

Country Link
US (1) US3916197A (ja)
JP (1) JPS5087395A (ja)
CA (1) CA1019975A (ja)
DE (1) DE2455870A1 (ja)
GB (1) GB1471969A (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58118948A (ja) * 1982-01-06 1983-07-15 Takeshi Nishisaka 分光分析による異常細胞の検出方法及び装置
JPS59205998A (ja) * 1983-05-09 1984-11-21 Mitsubishi Electric Corp メタン菌の菌数またはメタン生成活性の測定方法
WO1984004544A1 (en) * 1983-05-09 1984-11-22 Mitsubishi Electric Corp Method for measuring the number or methane-producing activity of methane bacteria
JPH01242962A (ja) * 1988-03-24 1989-09-27 Agency Of Ind Science & Technol 植物細胞核を標識する方法および装置
JPH06189740A (ja) * 1992-09-01 1994-07-12 Becton Dickinson & Co 微生物検出方法と装置

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437984B2 (de) * 1974-08-07 1976-06-10 Wilhelm Will Kg, Optisches Werk, 6331 Nauborn Verfahren zur kontrastverbesserung eines optischen mikroskopes
US4031398A (en) * 1976-03-23 1977-06-21 Research Corporation Video fluorometer
DE2732272C2 (de) * 1977-07-16 1979-07-05 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg Verfahren und Vorrichtung zur Fluoreszenzanalyse von gefärbten Partikeln, insbesondere biologischen Zellen
SE7806922L (sv) * 1978-06-15 1979-12-16 Svenska Traeforskningsinst Forfarande och anordning for att indikera storleksfordelningen av i ett strommande medium befintliga partiklar
US4172227A (en) * 1978-07-21 1979-10-23 Becton, Dickinson And Company Flow microfluorometer
US4242447A (en) * 1978-11-29 1980-12-30 Bioresearch Rapid detection of bacteria
US4354114A (en) * 1979-10-09 1982-10-12 Karnaukhov Valery N Apparatus for investigation of fluorescence characteristics of microscopic objects
US4500509A (en) * 1981-03-11 1985-02-19 Lawrence Kass Metachromatic dye sorption and fluorescent light emmisive means for differential determination of developmental stages of neutrophilic granulocytic cells and other leukocytes
GB2097144A (en) * 1981-03-23 1982-10-27 Tno New method for identifying algae in water samples and apparatus for use in that method
DE3219620A1 (de) * 1982-05-25 1983-12-01 Vsesojuznyj naučno-issledovatel'skij institut biosinteza belkovych veščestv, Moskva Verfahren zur ermittlung des verhaeltnisses von lebenden und toten zellen in hefesuspensionen
US4717655A (en) * 1982-08-30 1988-01-05 Becton, Dickinson And Company Method and apparatus for distinguishing multiple subpopulations of cells
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
JPS59184862A (ja) * 1983-04-05 1984-10-20 ベクトン・ディッキンソン・アンド・カンパニ− 試料内細胞の複数副次集団を識別する方法と装置
JPS60181637A (ja) * 1984-02-28 1985-09-17 Mitsubishi Electric Corp メタン菌の菌数またはメタン生成活性の測定方法
US4609286A (en) * 1984-04-16 1986-09-02 Becton, Dickinson And Company Dispersion prism for separation of wavelengths of spectrally rich light in a flow cytometry apparatus
JPS61186854A (ja) * 1985-02-14 1986-08-20 Fuji Photo Film Co Ltd 超純水中のバクテリア数測定装置
US4727020A (en) * 1985-02-25 1988-02-23 Becton, Dickinson And Company Method for analysis of subpopulations of blood cells
US5175109A (en) * 1986-09-10 1992-12-29 Toa Medical Electronics Co., Ltd. Reagent for classifying leukocytes by flow cytometry
US5039613A (en) * 1986-11-27 1991-08-13 Toa Medical Electronics Co., Ltd. Reagents used in a method of classifying leukocytes by flow cytometry
US5179026A (en) * 1986-11-27 1993-01-12 Toa Medical Electronics Co., Ltd. Method of classifying leukocytes by flow cytometry and reagents used in the method
DE3825352A1 (de) * 1988-07-26 1990-02-01 Kessler Manfred Verfahren und vorrichtung zur bestimmung von lokalen farbstoff-konzentrationen und von streuparametern in tierischen und menschlichen geweben
US5760900A (en) * 1989-03-18 1998-06-02 Canon Kabushiki Kaisha Method and apparatus for optically measuring specimen
JP3213333B2 (ja) * 1991-05-14 2001-10-02 シスメックス株式会社 尿中の細胞分析装置および方法。
JP3213334B2 (ja) * 1991-05-14 2001-10-02 シスメックス株式会社 尿中の細胞分析装置
US5999256A (en) * 1992-02-12 1999-12-07 Cambridge Consultants Limited Particle measurement system
CA2092373A1 (en) * 1992-04-24 1993-10-25 Klaus W. Berndt Methods and apparatus for detecting biological activities in a specimen
US6014213A (en) * 1994-12-12 2000-01-11 Visible Genetics Inc. High dynamic range apparatus for separation and detection of polynucleotide fragments
US5710628A (en) * 1994-12-12 1998-01-20 Visible Genetics Inc. Automated electrophoresis and fluorescence detection apparatus and method
US5608519A (en) * 1995-03-20 1997-03-04 Gourley; Paul L. Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells
US5793485A (en) * 1995-03-20 1998-08-11 Sandia Corporation Resonant-cavity apparatus for cytometry or particle analysis
US5733739A (en) * 1995-06-07 1998-03-31 Inphocyte, Inc. System and method for diagnosis of disease by infrared analysis of human tissues and cells
DE102007047093B4 (de) * 2007-10-01 2010-07-01 Ferton Holding S.A. Vorrichtung zur Messung von Fluoreszenzstrahlung an biologischen Substanzen mit einer Halbleitersensorenanordnung
EP2194368B1 (de) * 2008-12-03 2019-07-17 Grundfos Management A/S Sensorsystem zum Erfassen und Spezifizieren von einzelnen Partikeln in einem Fluid
WO2010068670A1 (en) 2008-12-09 2010-06-17 Advanced Analytical Technologies, Inc. Capillary electrophoresis fluorescent detection system
EP2236596B1 (en) * 2009-04-03 2012-07-25 Synoptics Limited High fidelity colour imaging of microbial colonies
US9423348B2 (en) 2011-06-24 2016-08-23 Becton, Dickinson And Company Absorbance spectrum scanning flow cytometry
CN104807792B (zh) * 2015-04-27 2017-06-30 电子科技大学 一种负折射率光子晶体型生物荧光探测器
WO2017106439A1 (en) 2015-12-18 2017-06-22 Abbott Laboratories Particle detection methods and systems for practicing same
DE112016007594B3 (de) * 2016-02-22 2021-06-10 Hitachi High-Tech Corporation Lichtemittierende detektionsvorrichtung
CN108700517B (zh) 2016-02-22 2021-12-03 株式会社日立高新技术 发光检测装置
US10436697B2 (en) * 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
US20220221391A1 (en) * 2019-05-30 2022-07-14 Sony Group Corporation Optical measuring device and optical measuring system
CN115135986A (zh) * 2020-02-19 2022-09-30 贝克顿·迪金森公司 频闪激光器激发系统及其使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3062963A (en) * 1960-09-29 1962-11-06 Amchem Prod Method of monitoring colored fluids
US3413464A (en) * 1965-04-29 1968-11-26 Ibm Method for measuring the nucleic acid in biological cells after enhancement in an acidic solution
US3470373A (en) * 1966-10-18 1969-09-30 Litton Systems Inc Method for analysis and identification of biologic entities by phosphorescence
US3497690A (en) * 1967-09-21 1970-02-24 Bausch & Lomb Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58118948A (ja) * 1982-01-06 1983-07-15 Takeshi Nishisaka 分光分析による異常細胞の検出方法及び装置
JPH0222331B2 (ja) * 1982-01-06 1990-05-18 Takeshi Nishisaka
JPS59205998A (ja) * 1983-05-09 1984-11-21 Mitsubishi Electric Corp メタン菌の菌数またはメタン生成活性の測定方法
WO1984004544A1 (en) * 1983-05-09 1984-11-22 Mitsubishi Electric Corp Method for measuring the number or methane-producing activity of methane bacteria
JPH01242962A (ja) * 1988-03-24 1989-09-27 Agency Of Ind Science & Technol 植物細胞核を標識する方法および装置
JPH06189740A (ja) * 1992-09-01 1994-07-12 Becton Dickinson & Co 微生物検出方法と装置

Also Published As

Publication number Publication date
GB1471969A (en) 1977-04-27
CA1019975A (en) 1977-11-01
DE2455870A1 (de) 1975-06-19
US3916197A (en) 1975-10-28

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