JPS5018482A - - Google Patents

Info

Publication number
JPS5018482A
JPS5018482A JP48059709A JP5970973A JPS5018482A JP S5018482 A JPS5018482 A JP S5018482A JP 48059709 A JP48059709 A JP 48059709A JP 5970973 A JP5970973 A JP 5970973A JP S5018482 A JPS5018482 A JP S5018482A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP48059709A
Other languages
Japanese (ja)
Other versions
JPS535678B2 (enrdf_load_stackoverflow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP5970973A priority Critical patent/JPS535678B2/ja
Priority to GB2367374A priority patent/GB1449708A/en
Priority to DE19742426304 priority patent/DE2426304A1/de
Priority to HUAA772A priority patent/HU170244B/hu
Priority to CH738274A priority patent/CH582695A5/xx
Priority to FR7418862A priority patent/FR2231388B1/fr
Publication of JPS5018482A publication Critical patent/JPS5018482A/ja
Publication of JPS535678B2 publication Critical patent/JPS535678B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP5970973A 1973-05-30 1973-05-30 Expired JPS535678B2 (enrdf_load_stackoverflow)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP5970973A JPS535678B2 (enrdf_load_stackoverflow) 1973-05-30 1973-05-30
GB2367374A GB1449708A (en) 1973-05-30 1974-05-28 N4-acylarabinonucleosides and the preparation thereof
DE19742426304 DE2426304A1 (de) 1973-05-30 1974-05-29 N-acyl-l-beta-d-arabinofuranosylcytosin-derivate, verfahren zu ihrer herstellung und arzneimittel
HUAA772A HU170244B (enrdf_load_stackoverflow) 1973-05-30 1974-05-29
CH738274A CH582695A5 (enrdf_load_stackoverflow) 1973-05-30 1974-05-30
FR7418862A FR2231388B1 (enrdf_load_stackoverflow) 1973-05-30 1974-05-30

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5970973A JPS535678B2 (enrdf_load_stackoverflow) 1973-05-30 1973-05-30

Publications (2)

Publication Number Publication Date
JPS5018482A true JPS5018482A (enrdf_load_stackoverflow) 1975-02-26
JPS535678B2 JPS535678B2 (enrdf_load_stackoverflow) 1978-03-01

Family

ID=13120999

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5970973A Expired JPS535678B2 (enrdf_load_stackoverflow) 1973-05-30 1973-05-30

Country Status (6)

Country Link
JP (1) JPS535678B2 (enrdf_load_stackoverflow)
CH (1) CH582695A5 (enrdf_load_stackoverflow)
DE (1) DE2426304A1 (enrdf_load_stackoverflow)
FR (1) FR2231388B1 (enrdf_load_stackoverflow)
GB (1) GB1449708A (enrdf_load_stackoverflow)
HU (1) HU170244B (enrdf_load_stackoverflow)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51143683A (en) * 1975-06-06 1976-12-10 Yamasa Shoyu Co Ltd A process for preparing n4- acylarabinofuranosyl cytosines
JPS5283910A (en) * 1975-12-31 1977-07-13 Asahi Chem Ind Co Ltd Solubilization of n4-behenoycytosine -behenoycytosine arabinoside
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2614946C2 (de) * 1975-04-08 1987-04-23 Asahi Kasei Kogyo K.K., Osaka Neue Nucleosidderivate
JPS552602A (en) * 1978-06-20 1980-01-10 Yamasa Shoyu Co Ltd 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester
JPS5622724A (en) * 1979-08-02 1981-03-03 Asahi Chem Ind Co Ltd Pharmaceutical preparation of n4-acylcytosine arabinoside
DE3323621A1 (de) * 1982-07-08 1984-03-01 Yamasa Shoyu K.K., Choshi, Chiba Pharmazeutisches praeparat mit die antitumor-wirkung verstaerkender wirkung, ein solches praeparat enthaltende chemotherapeutische zusammensetzung und verwendung des praeparates zur unterstuetzung der antitumor-behandlung beim menschen und tier
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
JP6104504B2 (ja) 2008-12-23 2017-03-29 ギリアド ファーマセット エルエルシー ヌクレオシド類似体
CL2009002206A1 (es) 2008-12-23 2011-08-26 Gilead Pharmasset Llc Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
CN102695513A (zh) 2008-12-23 2012-09-26 吉利德制药有限责任公司 核苷氨基磷酸酯
PT2752422T (pt) 2010-03-31 2017-11-07 Gilead Pharmasset Llc Síntese estereosseletiva de princípios ativos contendo fósforo
EP3453386A1 (en) 2017-09-08 2019-03-13 Universite D'angers Nanocapsules comprising modified nucleobases and/or nucleosides, hydrogels and oleogels comprising them and uses thereof
CN108409819A (zh) * 2018-04-25 2018-08-17 山东大学 一种新型阿糖胞苷前药DA-Ara纳米组装体的制备方法及应用
CN108727449A (zh) * 2018-04-25 2018-11-02 山东大学 一种新型阿糖胞苷前药MA-Ara纳米组装体的制备方法及应用
CN108610384B (zh) * 2018-05-31 2022-02-22 沈阳药科大学 基于肠道mct1载体蛋白设计的前药及其制备方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51143683A (en) * 1975-06-06 1976-12-10 Yamasa Shoyu Co Ltd A process for preparing n4- acylarabinofuranosyl cytosines
JPS5283910A (en) * 1975-12-31 1977-07-13 Asahi Chem Ind Co Ltd Solubilization of n4-behenoycytosine -behenoycytosine arabinoside
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法

Also Published As

Publication number Publication date
DE2426304A1 (de) 1975-01-02
HU170244B (enrdf_load_stackoverflow) 1977-05-28
GB1449708A (en) 1976-09-15
FR2231388A1 (enrdf_load_stackoverflow) 1974-12-27
CH582695A5 (enrdf_load_stackoverflow) 1976-12-15
JPS535678B2 (enrdf_load_stackoverflow) 1978-03-01
DE2426304C2 (enrdf_load_stackoverflow) 1988-03-17
FR2231388B1 (enrdf_load_stackoverflow) 1977-11-04

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