JPS50160300A - - Google Patents

Info

Publication number
JPS50160300A
JPS50160300A JP50059191A JP5919175A JPS50160300A JP S50160300 A JPS50160300 A JP S50160300A JP 50059191 A JP50059191 A JP 50059191A JP 5919175 A JP5919175 A JP 5919175A JP S50160300 A JPS50160300 A JP S50160300A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50059191A
Other languages
Japanese (ja)
Other versions
JPS582946B2 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS50160300A publication Critical patent/JPS50160300A/ja
Publication of JPS582946B2 publication Critical patent/JPS582946B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP50059191A 1974-06-06 1975-05-16 ８− チオメチルエルゴリンルイノ セイホウ Expired JPS582946B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US477136A US3901894A (en) 1974-06-06 1974-06-06 8-thiomethylergolines

Publications (2)

Publication Number Publication Date
JPS50160300A true JPS50160300A (fr) 1975-12-25
JPS582946B2 JPS582946B2 (ja) 1983-01-19

Family

ID=23894677

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50059191A Expired JPS582946B2 (ja) 1974-06-06 1975-05-16 ８− チオメチルエルゴリンルイノ セイホウ

Country Status (27)

Country Link
US (1) US3901894A (fr)
JP (1) JPS582946B2 (fr)
AR (1) AR210736A1 (fr)
AT (1) AT344333B (fr)
AU (1) AU507574B2 (fr)
BE (1) BE829887A (fr)
BG (1) BG24812A3 (fr)
CA (1) CA1071623A (fr)
CH (1) CH617196A5 (fr)
CS (1) CS199591B2 (fr)
DD (1) DD120438A5 (fr)
DE (1) DE2524575A1 (fr)
DK (1) DK144160C (fr)
ES (1) ES438313A1 (fr)
FR (1) FR2273542A1 (fr)
GB (1) GB1505296A (fr)
HU (1) HU173590B (fr)
IE (1) IE41474B1 (fr)
IL (1) IL47424A (fr)
NL (1) NL180911C (fr)
PH (1) PH10992A (fr)
PL (1) PL95738B1 (fr)
RO (1) RO77543A (fr)
SE (1) SE420095B (fr)
SU (1) SU613724A3 (fr)
YU (1) YU145575A (fr)
ZA (1) ZA753638B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
JPS54115400A (en) * 1978-02-08 1979-09-07 Lilly Co Eli 66nnpropyll88methoxymethyl or methylmercapto methylergolenes and their relative compounds

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (it) * 1977-07-05 1988-03-31 Simes Derivati di ergoline-2-tioeteri e loro solfossidi
US4180582A (en) * 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (de) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische zubereitungen mit zytostatischer wirkung
FR2526797A1 (fr) * 1982-05-12 1983-11-18 Roussel Uclaf Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (fr) * 1985-11-13 1988-09-02 Roussel Uclaf Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
ES2325880T3 (es) 2001-06-08 2009-09-23 Ipsen Pharma Analogos quimericos de somatostatina-dopamina.
WO2003078432A2 (fr) * 2002-03-15 2003-09-25 Antibioticos S.P.A. Procede de synthese de pergolide
CN104768565B (zh) 2012-11-01 2017-04-26 益普生制药股份有限公司 促生长素抑制素类似物及其二聚体
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
US20190374534A1 (en) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Liquid pharmaceutical compositions comprising pergolide

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5012398A (fr) * 1973-06-08 1975-02-07

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (fr) * 1967-03-16 1968-07-15
DE1935556A1 (de) * 1969-07-12 1971-01-21 Hoechst Ag Verfahren zur Herstellung von Lysergol

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5012398A (fr) * 1973-06-08 1975-02-07

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
JPS54115400A (en) * 1978-02-08 1979-09-07 Lilly Co Eli 66nnpropyll88methoxymethyl or methylmercapto methylergolenes and their relative compounds
JPS6363544B2 (fr) * 1978-02-08 1988-12-07

Also Published As

Publication number Publication date
YU145575A (en) 1982-02-28
CH617196A5 (fr) 1980-05-14
PH10992A (en) 1977-10-20
SE7506327L (sv) 1975-12-08
AR210736A1 (es) 1977-09-15
NL7506584A (nl) 1975-12-09
AU8182775A (en) 1976-12-09
GB1505296A (en) 1978-03-30
FR2273542A1 (fr) 1976-01-02
AU507574B2 (en) 1980-02-21
RO77543A (fr) 1982-02-26
NL180911C (nl) 1987-05-18
DK144160B (da) 1981-12-28
BG24812A3 (en) 1978-05-12
IL47424A0 (en) 1975-08-31
JPS582946B2 (ja) 1983-01-19
ES438313A1 (es) 1977-05-16
BE829887A (fr) 1975-12-05
DK249975A (da) 1975-12-07
IL47424A (en) 1979-11-30
IE41474L (en) 1975-12-06
DK144160C (da) 1982-06-07
AT344333B (de) 1978-07-10
CS199591B2 (en) 1980-07-31
SE420095B (sv) 1981-09-14
HU173590B (hu) 1979-06-28
CA1071623A (fr) 1980-02-12
US3901894A (en) 1975-08-26
DD120438A5 (fr) 1976-06-12
SU613724A3 (ru) 1978-06-30
DE2524575A1 (de) 1975-12-18
ATA427975A (de) 1977-11-15
FR2273542B1 (fr) 1978-10-06
PL95738B1 (pl) 1977-11-30
ZA753638B (en) 1977-01-26
IE41474B1 (en) 1980-01-16
NL180911B (nl) 1986-12-16

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