JPH1189789A - 蛍光画像装置 - Google Patents
蛍光画像装置Info
- Publication number
- JPH1189789A JPH1189789A JP9258758A JP25875897A JPH1189789A JP H1189789 A JPH1189789 A JP H1189789A JP 9258758 A JP9258758 A JP 9258758A JP 25875897 A JP25875897 A JP 25875897A JP H1189789 A JPH1189789 A JP H1189789A
- Authority
- JP
- Japan
- Prior art keywords
- image
- fluorescent
- color
- observation
- light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003902 lesion Effects 0.000 claims description 29
- 238000003384 imaging method Methods 0.000 claims description 24
- 238000002073 fluorescence micrograph Methods 0.000 claims description 23
- 239000003086 colorant Substances 0.000 claims description 10
- 238000005286 illumination Methods 0.000 claims description 10
- 230000001678 irradiating effect Effects 0.000 claims description 9
- 235000019646 color tone Nutrition 0.000 claims description 7
- 230000005284 excitation Effects 0.000 abstract description 40
- 201000010099 disease Diseases 0.000 abstract description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 6
- 238000012545 processing Methods 0.000 description 40
- 230000003287 optical effect Effects 0.000 description 14
- 238000010586 diagram Methods 0.000 description 11
- 206010028980 Neoplasm Diseases 0.000 description 6
- 201000011510 cancer Diseases 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- 238000003745 diagnosis Methods 0.000 description 4
- 238000012632 fluorescent imaging Methods 0.000 description 4
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- JOOXCMJARBKPKM-UHFFFAOYSA-N 4-oxopentanoic acid Chemical compound CC(=O)CCC(O)=O JOOXCMJARBKPKM-UHFFFAOYSA-N 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- FVTCRASFADXXNN-SCRDCRAPSA-N flavin mononucleotide Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O FVTCRASFADXXNN-SCRDCRAPSA-N 0.000 description 2
- 229940013640 flavin mononucleotide Drugs 0.000 description 2
- FVTCRASFADXXNN-UHFFFAOYSA-N flavin mononucleotide Natural products OP(=O)(O)OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O FVTCRASFADXXNN-UHFFFAOYSA-N 0.000 description 2
- 239000011768 flavin mononucleotide Substances 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 229910001507 metal halide Inorganic materials 0.000 description 2
- 150000005309 metal halides Chemical class 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000019231 riboflavin-5'-phosphate Nutrition 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- UJKPHYRXOLRVJJ-MLSVHJFASA-N CC(O)C1=C(C)/C2=C/C3=N/C(=C\C4=C(CCC(O)=O)C(C)=C(N4)/C=C4\N=C(\C=C\1/N\2)C(C)=C4C(C)O)/C(CCC(O)=O)=C3C Chemical compound CC(O)C1=C(C)/C2=C/C3=N/C(=C\C4=C(CCC(O)=O)C(C)=C(N4)/C=C4\N=C(\C=C\1/N\2)C(C)=C4C(C)O)/C(CCC(O)=O)=C3C UJKPHYRXOLRVJJ-MLSVHJFASA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010066054 Dysmorphism Diseases 0.000 description 1
- 206010058314 Dysplasia Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 238000000799 fluorescence microscopy Methods 0.000 description 1
- 229960003569 hematoporphyrin Drugs 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 229940040102 levulinic acid Drugs 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- VSQYNPJPULBZKU-UHFFFAOYSA-N mercury xenon Chemical compound [Xe].[Hg] VSQYNPJPULBZKU-UHFFFAOYSA-N 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229950006238 nadide Drugs 0.000 description 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 229940109328 photofrin Drugs 0.000 description 1
- 150000003222 pyridines Chemical class 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endoscopes (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9258758A JPH1189789A (ja) | 1997-09-24 | 1997-09-24 | 蛍光画像装置 |
| US09/153,793 US6422994B1 (en) | 1997-09-24 | 1998-09-15 | Fluorescent diagnostic system and method providing color discrimination enhancement |
| US10/045,979 US6790174B2 (en) | 1997-09-24 | 2002-01-10 | Fluorescent imaging device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9258758A JPH1189789A (ja) | 1997-09-24 | 1997-09-24 | 蛍光画像装置 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006333877A Division JP2007125403A (ja) | 2006-12-11 | 2006-12-11 | 蛍光画像装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH1189789A true JPH1189789A (ja) | 1999-04-06 |
| JPH1189789A5 JPH1189789A5 (enExample) | 2005-06-16 |
Family
ID=17324685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9258758A Pending JPH1189789A (ja) | 1997-09-24 | 1997-09-24 | 蛍光画像装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH1189789A (enExample) |
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001061764A (ja) * | 1999-08-25 | 2001-03-13 | Asahi Optical Co Ltd | 内視鏡装置 |
| JP2001070228A (ja) * | 1999-07-02 | 2001-03-21 | Asahi Optical Co Ltd | 内視鏡装置 |
| JP2003503135A (ja) * | 1999-07-02 | 2003-01-28 | ハイパーメッド イメイジング インコーポレイテッド | イメージング装置および試料分析方法 |
| US6821245B2 (en) | 2000-07-14 | 2004-11-23 | Xillix Technologies Corporation | Compact fluorescence endoscopy video system |
| US6899675B2 (en) | 2002-01-15 | 2005-05-31 | Xillix Technologies Corp. | Fluorescence endoscopy video systems with no moving parts in the camera |
| WO2006126318A1 (ja) | 2005-05-23 | 2006-11-30 | Olympus Medical Systems Corp. | 画像処理装置、内視鏡装置及びカラーバランス調整方法 |
| JP2007020727A (ja) * | 2005-07-13 | 2007-02-01 | Olympus Medical Systems Corp | 画像処理装置 |
| JP2009165889A (ja) * | 2009-05-07 | 2009-07-30 | Olympus Corp | 画像処理装置 |
| JP2016525905A (ja) * | 2013-05-17 | 2016-09-01 | エンドチョイス インコーポレイテッドＥｎｄｏｃｈｏｉｃｅ， Ｉｎｃ． | 複数ビュー素子内視鏡システムのインタフェースユニット |
| US9642532B2 (en) | 2008-03-18 | 2017-05-09 | Novadaq Technologies Inc. | Imaging system for combined full-color reflectance and near-infrared imaging |
| JPWO2017077882A1 (ja) * | 2015-11-04 | 2017-11-02 | オリンパス株式会社 | 画像処理装置、及び内視鏡システム |
| US9814378B2 (en) | 2011-03-08 | 2017-11-14 | Novadaq Technologies Inc. | Full spectrum LED illuminator having a mechanical enclosure and heatsink |
| US9877654B2 (en) | 2006-02-07 | 2018-01-30 | Novadaq Technologies Inc. | Near infrared imaging |
| JPWO2017150071A1 (ja) * | 2016-03-03 | 2018-03-15 | Hoya株式会社 | 補正データ生成方法及び補正データ生成装置 |
| US10182709B2 (en) | 2002-01-15 | 2019-01-22 | Novadaq Technologies ULC | Filter for use with imaging endoscopes |
| US10293122B2 (en) | 2016-03-17 | 2019-05-21 | Novadaq Technologies ULC | Endoluminal introducer with contamination avoidance |
| US10694152B2 (en) | 2006-12-22 | 2020-06-23 | Novadaq Technologies ULC | Imaging systems and methods for displaying fluorescence and visible images |
| US10869645B2 (en) | 2016-06-14 | 2020-12-22 | Stryker European Operations Limited | Methods and systems for adaptive imaging for low light signal enhancement in medical visualization |
| USD916294S1 (en) | 2016-04-28 | 2021-04-13 | Stryker European Operations Limited | Illumination and imaging device |
| US10980420B2 (en) | 2016-01-26 | 2021-04-20 | Stryker European Operations Limited | Configurable platform |
| US10992848B2 (en) | 2017-02-10 | 2021-04-27 | Novadaq Technologies ULC | Open-field handheld fluorescence imaging systems and methods |
| JP2022000163A (ja) * | 2018-06-04 | 2022-01-04 | 富士フイルム株式会社 | 画像処理装置、内視鏡システム、及び画像処理方法 |
| US11930278B2 (en) | 2015-11-13 | 2024-03-12 | Stryker Corporation | Systems and methods for illumination and imaging of a target |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63122421A (ja) * | 1986-11-12 | 1988-05-26 | 株式会社東芝 | 内視鏡装置 |
| JPS63240191A (ja) * | 1987-03-27 | 1988-10-05 | Toshiba Corp | 電子内視鏡装置 |
| JPH01101965A (ja) * | 1987-10-15 | 1989-04-19 | Olympus Optical Co Ltd | 経内視鏡分光診断装置 |
| JPH01280448A (ja) * | 1988-05-02 | 1989-11-10 | Olympus Optical Co Ltd | 経内視鏡分光診断装置 |
| JPH0380834A (ja) * | 1989-05-09 | 1991-04-05 | Olympus Optical Co Ltd | 内視鏡装置 |
| JPH0654792A (ja) * | 1991-05-08 | 1994-03-01 | Xillix Technol Corp | 撮像装置 |
| JPH07155291A (ja) * | 1993-12-03 | 1995-06-20 | Olympus Optical Co Ltd | 蛍光観察装置 |
| JPH07250812A (ja) * | 1994-03-15 | 1995-10-03 | Olympus Optical Co Ltd | 蛍光診断装置 |
-
1997
- 1997-09-24 JP JP9258758A patent/JPH1189789A/ja active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63122421A (ja) * | 1986-11-12 | 1988-05-26 | 株式会社東芝 | 内視鏡装置 |
| JPS63240191A (ja) * | 1987-03-27 | 1988-10-05 | Toshiba Corp | 電子内視鏡装置 |
| JPH01101965A (ja) * | 1987-10-15 | 1989-04-19 | Olympus Optical Co Ltd | 経内視鏡分光診断装置 |
| JPH01280448A (ja) * | 1988-05-02 | 1989-11-10 | Olympus Optical Co Ltd | 経内視鏡分光診断装置 |
| JPH0380834A (ja) * | 1989-05-09 | 1991-04-05 | Olympus Optical Co Ltd | 内視鏡装置 |
| JPH0654792A (ja) * | 1991-05-08 | 1994-03-01 | Xillix Technol Corp | 撮像装置 |
| JPH07155291A (ja) * | 1993-12-03 | 1995-06-20 | Olympus Optical Co Ltd | 蛍光観察装置 |
| JPH07250812A (ja) * | 1994-03-15 | 1995-10-03 | Olympus Optical Co Ltd | 蛍光診断装置 |
Cited By (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001070228A (ja) * | 1999-07-02 | 2001-03-21 | Asahi Optical Co Ltd | 内視鏡装置 |
| JP2003503135A (ja) * | 1999-07-02 | 2003-01-28 | ハイパーメッド イメイジング インコーポレイテッド | イメージング装置および試料分析方法 |
| JP2001061764A (ja) * | 1999-08-25 | 2001-03-13 | Asahi Optical Co Ltd | 内視鏡装置 |
| US9968244B2 (en) | 2000-07-14 | 2018-05-15 | Novadaq Technologies ULC | Compact fluorescence endoscopy video system |
| US6821245B2 (en) | 2000-07-14 | 2004-11-23 | Xillix Technologies Corporation | Compact fluorescence endoscopy video system |
| US7341557B2 (en) | 2000-07-14 | 2008-03-11 | Novadaq Technologies Inc. | Compact fluorescence endoscopy video system |
| US7722534B2 (en) | 2000-07-14 | 2010-05-25 | Novadaq Technologies, Inc. | Compact fluorescence endoscopy video system |
| US8961403B2 (en) | 2000-07-14 | 2015-02-24 | Novadaq Technologies Inc. | Compact fluorescence endoscopy video system |
| US6899675B2 (en) | 2002-01-15 | 2005-05-31 | Xillix Technologies Corp. | Fluorescence endoscopy video systems with no moving parts in the camera |
| US10182709B2 (en) | 2002-01-15 | 2019-01-22 | Novadaq Technologies ULC | Filter for use with imaging endoscopes |
| WO2006126318A1 (ja) | 2005-05-23 | 2006-11-30 | Olympus Medical Systems Corp. | 画像処理装置、内視鏡装置及びカラーバランス調整方法 |
| US8284245B2 (en) | 2005-05-23 | 2012-10-09 | Olympus Medical Systems Corp. | Image processing apparatus, endoscope apparatus and color balance adjusting method |
| JP2007020727A (ja) * | 2005-07-13 | 2007-02-01 | Olympus Medical Systems Corp | 画像処理装置 |
| US9877654B2 (en) | 2006-02-07 | 2018-01-30 | Novadaq Technologies Inc. | Near infrared imaging |
| US11770503B2 (en) | 2006-12-22 | 2023-09-26 | Stryker European Operations Limited | Imaging systems and methods for displaying fluorescence and visible images |
| US10694151B2 (en) | 2006-12-22 | 2020-06-23 | Novadaq Technologies ULC | Imaging system with a single color image sensor for simultaneous fluorescence and color video endoscopy |
| US10694152B2 (en) | 2006-12-22 | 2020-06-23 | Novadaq Technologies ULC | Imaging systems and methods for displaying fluorescence and visible images |
| US11025867B2 (en) | 2006-12-22 | 2021-06-01 | Stryker European Operations Limited | Imaging systems and methods for displaying fluorescence and visible images |
| US9642532B2 (en) | 2008-03-18 | 2017-05-09 | Novadaq Technologies Inc. | Imaging system for combined full-color reflectance and near-infrared imaging |
| US10779734B2 (en) | 2008-03-18 | 2020-09-22 | Stryker European Operations Limited | Imaging system for combine full-color reflectance and near-infrared imaging |
| JP2009165889A (ja) * | 2009-05-07 | 2009-07-30 | Olympus Corp | 画像処理装置 |
| US9814378B2 (en) | 2011-03-08 | 2017-11-14 | Novadaq Technologies Inc. | Full spectrum LED illuminator having a mechanical enclosure and heatsink |
| JP2016525905A (ja) * | 2013-05-17 | 2016-09-01 | エンドチョイス インコーポレイテッドＥｎｄｏｃｈｏｉｃｅ， Ｉｎｃ． | 複数ビュー素子内視鏡システムのインタフェースユニット |
| JPWO2017077882A1 (ja) * | 2015-11-04 | 2017-11-02 | オリンパス株式会社 | 画像処理装置、及び内視鏡システム |
| US10867410B2 (en) | 2015-11-04 | 2020-12-15 | Olympus Corporation | Image processing apparatus and endoscopic system |
| US11930278B2 (en) | 2015-11-13 | 2024-03-12 | Stryker Corporation | Systems and methods for illumination and imaging of a target |
| US10980420B2 (en) | 2016-01-26 | 2021-04-20 | Stryker European Operations Limited | Configurable platform |
| US11298024B2 (en) | 2016-01-26 | 2022-04-12 | Stryker European Operations Limited | Configurable platform |
| JPWO2017150071A1 (ja) * | 2016-03-03 | 2018-03-15 | Hoya株式会社 | 補正データ生成方法及び補正データ生成装置 |
| US10293122B2 (en) | 2016-03-17 | 2019-05-21 | Novadaq Technologies ULC | Endoluminal introducer with contamination avoidance |
| USD916294S1 (en) | 2016-04-28 | 2021-04-13 | Stryker European Operations Limited | Illumination and imaging device |
| USD1065550S1 (en) | 2016-04-28 | 2025-03-04 | Stryker Corporation | Device for illumination and imaging of a target |
| US11756674B2 (en) | 2016-06-14 | 2023-09-12 | Stryker European Operations Limited | Methods and systems for adaptive imaging for low light signal enhancement in medical visualization |
| US10869645B2 (en) | 2016-06-14 | 2020-12-22 | Stryker European Operations Limited | Methods and systems for adaptive imaging for low light signal enhancement in medical visualization |
| US10992848B2 (en) | 2017-02-10 | 2021-04-27 | Novadaq Technologies ULC | Open-field handheld fluorescence imaging systems and methods |
| US11140305B2 (en) | 2017-02-10 | 2021-10-05 | Stryker European Operations Limited | Open-field handheld fluorescence imaging systems and methods |
| US12028600B2 (en) | 2017-02-10 | 2024-07-02 | Stryker Corporation | Open-field handheld fluorescence imaging systems and methods |
| US12464215B2 (en) | 2017-02-10 | 2025-11-04 | Stryker Corporation | Open-field handheld fluorescence imaging systems and methods |
| JP2022000163A (ja) * | 2018-06-04 | 2022-01-04 | 富士フイルム株式会社 | 画像処理装置、内視鏡システム、及び画像処理方法 |
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