JPH1175863A5 - - Google Patents
Info
- Publication number
- JPH1175863A5 JPH1175863A5 JP1997322651A JP32265197A JPH1175863A5 JP H1175863 A5 JPH1175863 A5 JP H1175863A5 JP 1997322651 A JP1997322651 A JP 1997322651A JP 32265197 A JP32265197 A JP 32265197A JP H1175863 A5 JPH1175863 A5 JP H1175863A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- dna
- amino acid
- producing
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9322651A JPH1175863A (ja) | 1997-07-10 | 1997-11-25 | ２５−ヒドロキシビタミンＤ３−１α−水酸化酵素および該酵素をコードするＤＮＡ |
| US09/111,730 US6274359B1 (en) | 1997-07-10 | 1998-07-08 | 25-hydroxyvitamin D3-1α-hydroxylase and DNA encoding the hydroxylase |
| CA002237138A CA2237138A1 (en) | 1997-07-10 | 1998-07-09 | 25-hydroxyvitamin d3-1.alpha.-hydroxylase and dna encoding the hydroxylase |
| EP98112865A EP0890643A3 (en) | 1997-07-10 | 1998-07-10 | 25-Hydroxyvitamin D3-1a-hydroxylase and dna encoding the hydroxylase |
| EP00124552A EP1074627A3 (en) | 1997-07-10 | 1998-07-10 | 25-hydroxyvitamin D3-1a-hydroxylase and DNA encoding the hydroxylase |
| US09/878,262 US20020031798A1 (en) | 1997-07-10 | 2001-06-12 | Antibody recognizing human 25-hydroxyvitamin D3-1a-hydroxylase |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9-185399 | 1997-07-10 | ||
| JP18539997 | 1997-07-10 | ||
| JP9322651A JPH1175863A (ja) | 1997-07-10 | 1997-11-25 | ２５−ヒドロキシビタミンＤ３−１α−水酸化酵素および該酵素をコードするＤＮＡ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH1175863A JPH1175863A (ja) | 1999-03-23 |
| JPH1175863A5 true JPH1175863A5 (https=) | 2005-04-07 |
Family
ID=26503073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9322651A Pending JPH1175863A (ja) | 1997-07-10 | 1997-11-25 | ２５−ヒドロキシビタミンＤ３−１α−水酸化酵素および該酵素をコードするＤＮＡ |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US6274359B1 (https=) |
| EP (2) | EP1074627A3 (https=) |
| JP (1) | JPH1175863A (https=) |
| CA (1) | CA2237138A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999005292A1 (en) * | 1997-07-22 | 1999-02-04 | Chugai Seiyaku Kabushiki Kaisha | Method for gene screening with the use of nuclear receptors |
| US6096876A (en) * | 1997-08-06 | 2000-08-01 | Shriners Hospitals For Children | 1-α-hydroxylase materials and methods |
| CN1250563C (zh) | 1999-05-04 | 2006-04-12 | 斯特拉坎有限公司 | 雄激素糖苷及其产生雄性征的活性 |
| US20030062225A1 (en) * | 2001-10-03 | 2003-04-03 | Stucky Paul A. | Elevator load bearing assembly having a detectable element that is indicative of local strain |
| US7416899B2 (en) * | 2002-07-29 | 2008-08-26 | Tohoku Techno Arch Co., Ltd. | Method and apparatus for measuring trace ingredients in water |
| ES2593047T3 (es) | 2006-02-03 | 2016-12-05 | Opko Renal, Llc | Tratamiento de la insuficiencia y deficiencia de vitamina D con 25-hidroxivitamina D2 y 25-hidroxivitamina D3 |
| ES2670029T3 (es) | 2006-06-21 | 2018-05-29 | Opko Ireland Global Holdings, Ltd. | Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D |
| KR20190028822A (ko) | 2007-04-25 | 2019-03-19 | 사이토크로마 인코포레이티드 | 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물 |
| HUE073014T2 (hu) | 2007-04-25 | 2025-12-28 | Opko Renal Llc | Eljárás a másodlagos hyperparathyreoidismus biztonságos és hatékony kezelésére és megelõzésére krónikus vesebetegség esetén |
| US11752158B2 (en) | 2007-04-25 | 2023-09-12 | Eirgen Pharma Ltd. | Method of treating vitamin D insufficiency and deficiency |
| EP2281058B1 (en) | 2008-04-02 | 2016-06-29 | Opko Ireland Global Holdings, Ltd. | Methods, compositions, uses, and kits useful for vitamin d deficiency and related disorders |
| WO2011123476A1 (en) | 2010-03-29 | 2011-10-06 | Cytochroma Inc. | Methods and compositions for reducing parathyroid levels |
| WO2013123088A1 (en) * | 2012-02-14 | 2013-08-22 | Loma Linda University | Agents and method for treating inflammation-related conditions and diseases |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 ｄ 방출 제형 |
| US10220047B2 (en) | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
| US10577669B2 (en) | 2015-02-11 | 2020-03-03 | Loma Linda University | Method for utilizing engineered dendritic cells to induce gut-homing regulatory T cells and treat gut inflammation |
| JP7032322B2 (ja) | 2016-03-28 | 2022-03-08 | オプコ アイルランド グローバル ホールディングス リミテッド | ビタミンｄ治療法 |
| WO2017214190A1 (en) * | 2016-06-06 | 2017-12-14 | Loma Linda University | Engineered dendritic cells that express 1a-hydroxylase and uses thereof for treating immune-mediated diseases |
| CN107365805B (zh) * | 2017-05-12 | 2021-08-03 | 太原市威尔潞威科技发展有限公司 | 骨化二醇发酵的补料培养基、发酵的补料方法及其发酵方法 |
| CN114075556B (zh) * | 2021-11-18 | 2023-08-04 | 江南大学 | 可羟基化维生素d3 c-1和c-25的p450酶及其基因、表达载体、重组菌与应用 |
| CN116426595A (zh) * | 2023-04-10 | 2023-07-14 | 北京泛球生物科技有限公司 | 一种利用固定化羟化酶转化制备25-羟基维生素d3的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554106A (en) | 1984-11-01 | 1985-11-19 | Wisconsin Alumni Research Foundation | Method for preparing 1α-hydroxyvitamin D compounds |
| JP3024154B2 (ja) * | 1990-02-06 | 2000-03-21 | 住友化学工業株式会社 | チトクロムＰ４５０ｃ▲下２▼▲下５▼遺伝子 |
| DE69122016T2 (de) | 1990-09-26 | 1997-04-30 | Sumitomo Chemical Co | Mitochondriales P450 |
| US5786191A (en) * | 1992-04-09 | 1998-07-28 | Goldstein; Joyce A. | Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450 2C subfamily |
| US5981176A (en) * | 1992-06-17 | 1999-11-09 | City Of Hope | Method of detecting and discriminating between nucleic acid sequences |
| DK0652975T3 (da) * | 1992-07-31 | 2005-02-14 | Garvan Inst Med Res | Vurdering af allelvariation med hensyn til trans-virkende faktorer |
| WO1999005292A1 (en) | 1997-07-22 | 1999-02-04 | Chugai Seiyaku Kabushiki Kaisha | Method for gene screening with the use of nuclear receptors |
| US6096876A (en) * | 1997-08-06 | 2000-08-01 | Shriners Hospitals For Children | 1-α-hydroxylase materials and methods |
| CA2323782A1 (en) | 1998-03-25 | 1999-09-30 | Cutanogen, Inc. | Methods for prevention and treatment of cancer |
-
1997
- 1997-11-25 JP JP9322651A patent/JPH1175863A/ja active Pending
-
1998
- 1998-07-08 US US09/111,730 patent/US6274359B1/en not_active Expired - Fee Related
- 1998-07-09 CA CA002237138A patent/CA2237138A1/en not_active Abandoned
- 1998-07-10 EP EP00124552A patent/EP1074627A3/en not_active Withdrawn
- 1998-07-10 EP EP98112865A patent/EP0890643A3/en not_active Withdrawn
-
2001
- 2001-06-12 US US09/878,262 patent/US20020031798A1/en not_active Abandoned
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