JP2023538112A5 - - Google Patents
Info
- Publication number
- JP2023538112A5 JP2023538112A5 JP2023512371A JP2023512371A JP2023538112A5 JP 2023538112 A5 JP2023538112 A5 JP 2023538112A5 JP 2023512371 A JP2023512371 A JP 2023512371A JP 2023512371 A JP2023512371 A JP 2023512371A JP 2023538112 A5 JP2023538112 A5 JP 2023538112A5
- Authority
- JP
- Japan
- Prior art keywords
- manipulated
- polynucleotide
- acid sequence
- meganuclease
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025126866A JP2025172742A (ja) | 2020-08-21 | 2025-07-30 | トランスサイレチン遺伝子における認識配列に対する特異性を有する操作されたメガヌクレアーゼ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063068965P | 2020-08-21 | 2020-08-21 | |
| US63/068,965 | 2020-08-21 | ||
| PCT/US2021/046987 WO2022040582A1 (en) | 2020-08-21 | 2021-08-20 | Engineered meganucleases having specificity for a recognition sequence in the transthyretin gene |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025126866A Division JP2025172742A (ja) | 2020-08-21 | 2025-07-30 | トランスサイレチン遺伝子における認識配列に対する特異性を有する操作されたメガヌクレアーゼ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023538112A JP2023538112A (ja) | 2023-09-06 |
| JP2023538112A5 true JP2023538112A5 (https=) | 2024-08-01 |
| JP7721637B2 JP7721637B2 (ja) | 2025-08-12 |
Family
ID=77726580
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023512371A Active JP7721637B2 (ja) | 2020-08-21 | 2021-08-20 | トランスサイレチン遺伝子における認識配列に対する特異性を有する操作されたメガヌクレアーゼ |
| JP2025126866A Pending JP2025172742A (ja) | 2020-08-21 | 2025-07-30 | トランスサイレチン遺伝子における認識配列に対する特異性を有する操作されたメガヌクレアーゼ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025126866A Pending JP2025172742A (ja) | 2020-08-21 | 2025-07-30 | トランスサイレチン遺伝子における認識配列に対する特異性を有する操作されたメガヌクレアーゼ |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240011003A1 (https=) |
| EP (1) | EP4200412B1 (https=) |
| JP (2) | JP7721637B2 (https=) |
| AU (1) | AU2021329403A1 (https=) |
| CA (1) | CA3172292A1 (https=) |
| WO (1) | WO2022040582A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250064986A1 (en) | 2022-01-07 | 2025-02-27 | Precision Biosciences, Inc. | Optimized polynucleotides for protein expression |
| CN116083485B (zh) * | 2022-12-01 | 2024-09-13 | 四川大学华西医院 | 一种靶向载体、ATTRm疾病模型的构建方法及其应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| US6015832A (en) | 1997-12-31 | 2000-01-18 | The Regents Of The University Of Michigan | Methods of inactivating bacteria including bacterial spores |
| US6635676B2 (en) | 1999-04-28 | 2003-10-21 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
| US7767216B2 (en) | 1999-04-28 | 2010-08-03 | The Regents Of The University Of Michigan | Antimicrobial compositions and methods of use |
| US6506803B1 (en) | 1999-04-28 | 2003-01-14 | Regents Of The University Of Michigan | Methods of preventing and treating microbial infections |
| US6559189B2 (en) | 1999-04-28 | 2003-05-06 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
| US6555674B2 (en) | 2000-08-09 | 2003-04-29 | Nsgene A/S | JeT promoter |
| US7074596B2 (en) | 2002-03-25 | 2006-07-11 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Synthesis and use of anti-reverse mRNA cap analogues |
| EP3202899B1 (en) * | 2003-01-28 | 2020-10-21 | Cellectis | Custom-made meganuclease and use thereof |
| US7404969B2 (en) | 2005-02-14 | 2008-07-29 | Sirna Therapeutics, Inc. | Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules |
| PL2578685T3 (pl) | 2005-08-23 | 2020-01-31 | The Trustees Of The University Of Pennsylvania | Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania |
| ES2582091T3 (es) | 2005-10-18 | 2016-09-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| WO2009001159A1 (en) | 2007-06-25 | 2008-12-31 | Cellectis | Method for enhancing the cleavage activity of i-crei derived meganucleases |
| EP2215223B1 (en) | 2007-10-31 | 2013-05-01 | Precision Biosciences, Inc. | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences |
| PL2563920T3 (pl) | 2010-04-29 | 2017-08-31 | Ionis Pharmaceuticals, Inc. | Modulacja ekspresji transtyretyny |
| EP2714936B1 (en) | 2011-06-01 | 2018-12-12 | Precision Biosciences, Inc. | Methods and products for producing engineered mammalian cell lines with amplified transgenes |
| CA3009637A1 (en) * | 2015-12-23 | 2017-06-29 | Precision Biosciences, Inc. | Engineered meganucleases with recognition sequences found in the human beta-2 microglobulin gene |
| WO2019089913A1 (en) * | 2017-11-01 | 2019-05-09 | Precision Biosciences, Inc. | Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a |
| WO2019185920A1 (en) * | 2018-03-29 | 2019-10-03 | Cellectis | Tale-nucleases for allele-specific codon modification |
-
2021
- 2021-08-20 US US18/022,247 patent/US20240011003A1/en active Pending
- 2021-08-20 WO PCT/US2021/046987 patent/WO2022040582A1/en not_active Ceased
- 2021-08-20 EP EP21769604.6A patent/EP4200412B1/en active Active
- 2021-08-20 AU AU2021329403A patent/AU2021329403A1/en active Pending
- 2021-08-20 CA CA3172292A patent/CA3172292A1/en active Pending
- 2021-08-20 JP JP2023512371A patent/JP7721637B2/ja active Active
-
2025
- 2025-07-30 JP JP2025126866A patent/JP2025172742A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7793525B2 (ja) | コロナウイルスワクチン | |
| AU2025200483A1 (en) | Coronavirus vaccine | |
| WO2012172277A4 (en) | Simian adenovirus and hybrid adenoviral vectors | |
| WO2020002525A1 (en) | Novel lassa virus rna molecules and compositions for vaccination | |
| JP2008545406A5 (https=) | ||
| WO2017192750A1 (en) | Recombinant adeno-associated viral vectors | |
| JP2023538112A5 (https=) | ||
| JP2024180560A5 (https=) | ||
| JP2016513115A5 (https=) | ||
| Rahman et al. | An overview on the development of mRNA-based vaccines and their formulation strategies for improved antigen expression in vivo | |
| MX2020000221A (es) | Secuencias de aminoacidos y de acidos nucleicos de adenovirus de grandes simios no humanos, vectores que contienen las mismas y usos de las mismas. | |
| US20250223592A1 (en) | Compositions and methods for circular rna affinity purification | |
| WO2023035372A1 (zh) | 一种有限自我复制mRNA分子系统、制备方法及应用 | |
| JP2024511206A (ja) | 免疫原性組成物 | |
| WO2023227124A1 (zh) | 一种构建mRNA体外转录模板的骨架 | |
| JP2026063215A5 (https=) | ||
| JP2023521662A5 (https=) | ||
| Wei et al. | Technological breakthroughs and advancements in the application of mRNA vaccines: a comprehensive exploration and future prospects | |
| Huang et al. | Circular mrna vaccine against sars-cov-2 variants enabled by degradable lipid nanoparticles | |
| CN100471957C (zh) | 用于免疫治疗的腺病毒载体 | |
| JP2025170345A5 (https=) | ||
| CN101155826B (zh) | 作为疫苗的复制缺陷型rna病毒 | |
| MX2022016287A (es) | Secuencias de acidos nucleicos y de aminoacidos de adenovirus de gorila, vectores que contienen las mismas y usos de las mismas. | |
| Xu et al. | From sequence to system: Enhancing IVT mRNA vaccine effectiveness through cutting-edge technologies | |
| US20160120974A1 (en) | Semi-live respiratory syncytial virus vaccine |