JPH1160462A - Skin cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a skin cosmetic, capable of manifesting excellent stability without regard to the use of a synthetic surfactant together with humectant effects and useful as a cream, a pack, a bathing agent or the like by formulating a specific cholesterol ester with a hydrogenated lecithin. SOLUTION: This skin cosmetic is obtained by formulating (A) a cholesterol ester of an iso type fatty acid represented by formula I (n) is 6-32} or an anteiso type fatty acid represented by substitute II and (B) a hydrogenated lecithin such as a hydrogenated lecithin derived from soybean or a hydrogenated lecithin derived from an egg yolk. For example, the respective amounts of the formulated ingredients based on the total weight of the cosmetic are 0.005-20 wt.% ingredient A and 0.001-5 wt.% ingredient B. Since the ingredients are combined, the ingredient A can stably be kept in the formulation and both are further capable of synergstically acting on skin and achieving the objective various effects.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a skin cosmetic which has excellent moisture retention and can be prepared regardless of the use of a synthetic surfactant.

[0002]

BACKGROUND OF THE INVENTION Skin cosmetics contain a moisturizing agent as an essential component for maintaining skin homeostasis and preventing and improving dry skin. The moisturizing ability, which is one of the functions, is the most basic performance, and is expected to not only smooth the skin by increasing the amount of keratin moisture after application, but also have an anti-aging effect and a beautiful skin effect.

[0003] Moisturizers conventionally used include:
Examples thereof include polyhydric alcohols such as glycerin, sorbitol, and propylene glycol, and water-soluble substances such as amino acids, sugars, and hyaluronic acid. However, the moisturizing ability of these moisturizing agents is not always high, and in order to obtain a sufficient moisturizing effect, it is necessary to mix them at a high concentration, which gives a sticky feeling and is not preferable in terms of sensory characteristics. Therefore, moisturizing oils such as ceramide and cholesterol ester have recently been used. Branched fatty acid cholesterol esters, one of the moisturizing oils, have been shown to have high water hydration. However, branched fatty acid cholesterol ester is easily precipitated from the preparation,
It was difficult to mix at a high concentration.

An object of the present invention is to develop a novel skin cosmetic which is excellent in moisture retention and which can be prepared irrespective of the use of a synthetic surfactant or not.

[0005]

DISCLOSURE OF THE INVENTION The present inventors have conducted intensive studies in view of the above-mentioned circumstances, and as a result, have found that cholesterol esters of iso-form fatty acids represented by the general formula (1) and / or The present inventors have found that a skin cosmetic characterized by blending a cholesterol ester of an anteiso fatty acid represented by (2) and hydrogenated lecithin can achieve the object.

[0006]

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(However, n is represented by 6 to 32.)

[0008]

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(However, n is represented by 6 to 32.)

That is, as described above, the skin cosmetic of the present invention can stably maintain the branched fatty acid cholesterol ester in the preparation by combining the specific branched fatty acid cholesterol ester with hydrogenated lecithin. The two act synergistically on the skin to give the skin excellent moisturizing properties and exhibit a remarkable stabilizing effect irrespective of the use of synthetic surfactants.

[0011]

Embodiments of the present invention will be described below in detail.

[0012] The branched fatty acid cholesterol ester conventionally used as a cosmetic raw material is composed of isostearic acid. This isostearic acid is mostly 2-heptylundecanoic acid, although the branch position and the branched alkyl chain length are not specified. On the other hand, the branched fatty acid cholesterol ester disclosed in the present invention is composed of iso-type and anteiso-type fatty acids. That is, it is limited to fatty acids having a methyl group at the 2-position from the terminal [the above-mentioned general formula (1)] and the 3-position from the terminal [the above-mentioned general formula (2)]. The branched fatty acid cholesterol ester of the present invention differs from the conventionally known branched fatty acid cholesterol ester in that the branch position and the branched alkyl chain length are specified.

The branched fatty acid cholesterol ester used in the present invention need not be separated into an iso form and an ante iso form, but may be used separately. In addition, these branched fatty acid cholesterol esters may be a mixture with other fatty acid cholesterol esters, or may be composed of only branched fatty acid cholesterol esters. Examples of the cholesterol ester of the iso-type fatty acid and / or anteiso-type fatty acid used in the present invention include, for example, YOFCO CLE-NH (containing cholesterol ester of iso-type fatty acid and anteiso-type fatty acid) of Nippon Seika. Yes, but not limited to this. The total carbon number of these iso-fatty acids and anteiso-fatty acids has a low melting point and is in a range for forming a liquid crystal structure.
32, preferably 12 to 28 carbon atoms in total. The amount of the branched fatty acid cholesterol ester is preferably 0.005 to 20% by weight (hereinafter abbreviated as wt%) based on the total amount of the skin cosmetic. More preferably 0.0
1 to 20 wt%.

The hydrogenated lecithin used in the present invention is a known compound, and soybean, egg yolk and the like are applied as a source of lecithin. The amount of the hydrogenated lecithin is preferably 0.001 to 5% by weight based on the total amount of the skin cosmetic.

The cosmetics of the present invention include, in addition to the above-mentioned raw materials, tar pigments, coloring pigments such as iron oxide, preservatives such as paraben and phenoxyethanol, fatty acids such as stearic acid, myristic acid and isostearic acid, and sodium cetyl sulfate. , N-stearoyl-L-glutamate, anionic surfactants such as glycyrrhizinate, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene polyhydric alcohol fatty acid ester, polyoxyethylene hydrogenated castor oil, Nonionic surfactants such as polyhydric alcohol fatty acid esters, polyglycerin fatty acid esters, modified silicones, sucrose esters, etc., cationic surfactants such as tetraalkylammonium salts, betaine type, sulfobetaine type, sulfoamino acid type, N-stearoyl Amphoteric surfactants such as sodium L-glutamate; natural surfactants such as lecithin and lysophosphatidylcholine; pigments such as titanium oxide and zinc oxide; antioxidants such as dibutylhydroxytoluene; glycerin; Polyhydric alcohols such as butylene glycol, dipropylene glycol, propylene glycol, sorbitol, malbitol, and diglycerin;
Chelating agents such as edetic acid, liquid paraffin, squalane, paraffin, hydrocarbons such as petrolatum, triglycerides such as glyceryl triisostearate and glyceryl tri-2-ethylhexanoate, octyldodecyl myristate, isocetyl myristate, cetyl palmitate and the like Ester oils, higher alcohols such as cetanol, behenyl alcohol, stearyl alcohol, cholesterol, sterols such as phytosterol, beeswax,
Waxes such as jojoba oil, thickeners such as xanthan gum, carboxyvinyl polymer, carrageenan, neutralizing agents such as potassium hydroxide, diisopropanolamine and triethanolamine, biopolymers such as hyaluronic acid and collagen, chamomile and aloe , Plant extracts such as peach, carrot and licorice, amino acids such as serine and threonine, ultraviolet absorbers such as hydroxymethoxybenzophenone sulfonate and the like can be appropriately compounded within a range that achieves the object of the present invention.

The form of the skin cosmetic of the present invention includes creams, emulsions, lotions, packs, massages, make-ups, baths and the like.

[0017]

The present invention will be described below in detail based on examples and comparative examples. In addition, the moisturizing test (method of measuring the water content of the stratum corneum), the preparation stability test, and the sensory test (odor) described in Examples are as follows.

Moisturizing test (method of measuring the amount of water in the stratum corneum) The water content of the stratum corneum before and after 15 minutes of application of the sample was determined by the method of Tagami et al.
6, No. 2, pp. 100-106, 1982) using a Skicon-200 type moisture meter (manufactured by IBS), and evaluated by the number of persons whose keratin moisture content after application increased.

Formulation stability test Emulsion state and appearance of the sample after standing at room temperature for 2 days are visually observed, and when an abnormality is observed (when oil is separated or particles become coarse), it is represented by "x". When no abnormality was observed even after standing for one month (when the emulsified state was uniform and a uniform emulsion was formed), it was regarded as good and represented by “○”.

Sensory Test (Odor) Since a preparation containing hydrogenated lecithin and similar egg yolk lecithin generates "odor" over time, this test was conducted after the preparation stability test described in the preceding paragraph. That is, a sample was applied to the face of 20 female subjects (35 to 55 years old),
The evaluation was performed by the number of persons who felt an unpleasant smell.

Examples 1 and 2 and Comparative Examples 1 and 2 [Lotion] Lotions having the compositions shown in Table 1 were prepared, and the above-described experiments were carried out. In addition, as a cholesterol ester of an iso-type fatty acid and / or anteiso-type fatty acid, YOFCOLE-
NH (manufactured by Nippon Seika Co., Ltd .; hereinafter, abbreviated as “NH”) was used.

[0022]

[Table 1]

(1) Preparation Method All components were mixed at 80 ° C., dissolved by heating, and then cooled to 30 ° C. while stirring to prepare each lotion.

(2) Characteristics The results of various tests of each lotion are shown in Table 1.

From Table 1, it can be seen that the lotions containing NH and hydrogenated lecithin of Examples 1 and 2 of the present invention had remarkable effects on all the properties. On the other hand, in Comparative Example 1 in which only NH, which is one of the essential components of the present invention, was blended, the preparation stability was poor, but the functionality (odor) was good. Further, the lotion containing NH and egg yolk lecithin without the addition of hydrogenated lecithin, which is an essential component of the present invention in Comparative Example 2, was prepared in Comparative Example 1.
Conversely, the formulation stability was good, but the sensory (odor) was bad.

Examples 3 to 7 and Comparative Examples 3 to 4 [Emulsion] Each emulsion having the composition shown in Table 2 was prepared, and the above-mentioned tests were carried out.

[0027]

[Table 2]

(1) Preparation method After each of the components (A) and (B) are uniformly dissolved at 80 ° C,
The component (B) was added to the component (A) and mixed, stirred, and dispersed. Subsequently, the emulsion was cooled to 30 ° C. while stirring.

(2) Characteristics The results of various tests performed on each emulsion are shown in Table 2.

From Table 2, it can be seen that the emulsions containing Examples 3 to 7 of the present invention containing NH and hydrogenated lecithin had remarkable effects on various properties. On the other hand, the emulsions of Comparative Examples 3 and 4 not containing NH or not containing hydrogenated lecithin could not obtain a sufficient effect. In particular, Comparative Example 4, which did not contain hydrogenated lecithin, had poor formulation stability. From the results of Examples 3 to 7, one of the objects of the present invention, a stable preparation was obtained without using a synthetic surfactant.

Examples 8 to 10 [Serum] Each serum was prepared according to the composition shown in Table 3, and the above-mentioned tests were carried out.

[0032]

[Table 3]

(1) Preparation method All components were mixed at 80 ° C., dissolved by heating, and then cooled to 30 ° C. with stirring to prepare each serum.

(2) Characteristics Table 3 also shows the results of various tests performed on each serum.

From Table 3, Examples 8 to 10 showed good results in all of the items of the above tests. In particular, Example 9 in which the amount of hydrogenated lecithin was kept constant and a large amount of NH was blended showed remarkable results.

Examples 11 to 13 and Comparative Example 5 [Skin cream] Each skin cream having the composition shown in Table 4 was prepared, and the above-mentioned tests were carried out.

[0037]

[Table 4]

(1) Preparation method After each of the components (A) and (B) are uniformly dissolved at 80 ° C,
The component (B) was added to the component (A) and mixed, stirred, and dispersed. Next, the mixture was cooled to 30 ° C. with stirring to prepare a skin cream.

(2) Characteristics The results of various tests conducted on each skin cream are shown in Table 4.

From Table 4, Examples 11 to 13 showed good results for all the items of the above tests. Among them,
Examples 12 and 13 are cases where the amounts of NH and hydrogenated lecithin, which are essential components of the present invention, were increased, and the moisturizing effect and the stability of the preparations were particularly remarkable. On the other hand, Comparative Example 5
Is an example in which polyoxyethylene (60EO) hydrogenated castor oil, which is commonly used in the cosmetics field, is blended as a synthetic surfactant, but the stability of the preparation is good, but the moisture retention is poor. From this, as with the emulsion described above, one of the objects of the present invention, even without using a synthetic surfactant,
It was found that a stable preparation could be obtained.

[0041]

As described above, the skin cosmetic of the present invention provides a skin cosmetic having excellent moisture retention and excellent stability, which can be prepared with or without the use of a synthetic surfactant. It is clear that.

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[Procedure amendment]

[Submission date] October 20, 1997

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0013

[Correction method] Change

[Correction contents]

The branched fatty acid cholesterol ester used in the present invention need not be separated into an iso form and an ante iso form, but may be used separately. These branched fatty acid cholesterol ester may be a mixture with other fatty acid cholesterol ester, or may consist solely of branched fatty acid cholesterol ester. Examples of the cholesterol ester of the iso-type fatty acid and / or anteiso-type fatty acid used in the present invention include, for example, YOFCO CLE-NH (containing cholesterol ester of iso-type fatty acid and anteiso-type fatty acid) of Nippon Seika. Yes, but not limited to this.
The total number of carbon atoms of these isoforms fatty acids and anteiso fatty acids is in the range of low melting point to form a liquid crystal structure, 1
0 to 37 , preferably 12 to 28 carbon atoms in total. The amount of the branched fatty acid cholesterol ester is preferably 0.005 to 20% by weight (hereinafter abbreviated as wt%) based on the total amount of the skin cosmetic. More preferably, it is 0.01 to 20 wt%.

 ──────────────────────────────────────────────────続 き Continuing on the front page (72) Inventor Yumi Togitsu 5-3-28 Kotobukicho, Odawara-shi, Kanagawa Kanebo Cosmetics Research Institute

Claims (1)

[Claims] 1. A compound of the general formula (1) (Where n is 6 to 32) cholesterol ester of iso-fatty acid and / or general formula (2) (Where n is 6 to 32). A skin cosmetic comprising a cholesterol ester of anteiso fatty acid represented by the formula: and hydrogenated lecithin.