JP2013136544A - Gelled skin care preparation - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a gelled skin care preparation which has no sticky feeling, has satisfactory skin fitness, has a delicately coated feeling, has excellent maintainability of a moisturizing feeling and also has satisfactory preservation stability, on application.SOLUTION: The gelled skin care preparation includes the following (A) to (D) components: (A) phospholipid; (B) one or two or more kinds selected from a carboxyvinyl polymer, an acrylic acid-methacrylic acid alkyl copolymer and their salts; (C) the fatty acid ester of cholesterol or phytosterol; and (D) a 1 to 3C saturated monohydric alcohol.

Description

  The present invention relates to a gel-like external preparation for skin having excellent moisturizing feeling and skin conformability, and having a good feeling with reduced stickiness.

Gel (also referred to as jelly or gel) dosage forms are fresh and have a refreshing feeling of use, and thus are used in various skin external preparations such as pharmaceuticals and cosmetics. In such a gel-like external preparation for skin, a water-soluble polymer such as carboxyvinyl polymer is often used as a thickener. And in order to raise a moisturizing feeling, the gel-form skin external preparation which used the high concentration polyhydric alcohol together is proposed (refer patent document 1).
However, a gel-like external preparation for skin that does not contain an oil agent using a water-soluble polymer such as carboxyvinyl polymer cannot suppress moisture transpiration from the skin, and thus it is difficult to maintain a moisturizing feeling for a long time. Moreover, the sticky feeling originating in water-soluble polymer may be felt strongly.

  In recent years, gel cosmetics using phospholipids that have good affinity for skin, little irritation, and excellent moisture retention have been proposed (see Patent Documents 2 and 3).

JP 2010-64986 A JP 2005-320285 A JP 2008-7430 A

However, the gel-type skin external preparation containing a nonionic surfactant having a phospholipid and a glycerin skeleton and water described in Patent Document 2 gives a sense of irritation and sliminess due to the surfactant, and moisturizes for a long time. It was difficult to give a feeling.
Moreover, in the gel-form skin external preparation containing the phospholipid, the higher alcohol, and water described in Patent Document 3, a certain moisturizing feeling is obtained, but the effect is not satisfactory. In addition, skin familiarity was poor and the feeling of use was not satisfactory.

  Therefore, the problem of the present invention is that gel-like skin external use has no sticky feeling at the time of application, has good skin familiarity, has a supple film feeling, has excellent moisturizing feeling, and has good storage stability. It is to provide an agent.

  Therefore, the present inventor has made various studies on the gel structure in the gel-like external preparation for skin, and (B) one type selected from carboxyvinyl polymer, acrylic acid / alkyl methacrylate copolymer, and salts thereof, or Application by adding (A) a phospholipid, (C) a fatty acid ester of cholesterol or phytosterol, and (D) a saturated monohydric alcohol having 1 to 3 carbon atoms to a structure of two or more water-soluble polymers A gel-like structure with no stickiness, good skin fit, a supple film feel, excellent moisturizing feeling and good storage stability was found, and the present invention was completed. .

That is, this invention relates to the gel-form skin external preparation characterized by containing the following (A)-(D).
(A) Phospholipid (B) carboxyvinyl polymer, acrylic acid / alkyl methacrylate copolymer, and one or more selected from these salts (C) Cholesterol or phytosterol fatty acid ester (D) 1 carbon number ~ 3 saturated monohydric alcohol

  The external preparation for gel-like skin of the present invention has no stickiness when applied, has good skin familiarity, has a supple film feeling, and is excellent in sustainability of moisturizing feeling. Also, the storage stability is good. It is possible to provide a gel skin external preparation useful as a pharmaceutical or cosmetic.

Hereinafter, embodiments of the present invention will be described in detail.
In the present invention, the gel-like skin external preparation refers to a skin external preparation composition in which viscosity is imparted to an arbitrary liquid medium containing water. The viscosity is preferably 15000 mPa · s or more, more preferably 15000 to 50000 mPa.s, at 25 ° C. and 1 atm, using a B-type viscometer (rotor No. 4, rotation speed 12, measurement time 30 seconds). s, more preferably 20000 to 45000 mPa · s. Since such gel-like external preparation for skin has an appropriate viscosity when taken in hand, it is easy to scrub with fingers and easy to apply to the skin.

  The phospholipid (A) in the present invention is preferably a phospholipid having a phosphatidylcholine content of 60% by mass or more in the phospholipid. A phospholipid having a phosphatidylcholine content of 65% by mass or more, more preferably 70% by mass or more is preferable. Examples of phospholipid components other than phosphatidylcholine include phosphatidic acid, phosphatidylserine, phosphatidylethanolamine, phosphatidylinositol, and phosphatidylglycerol.

  The phospholipid used in the present invention may be a natural product extracted and purified from animals and plants, or may be chemically synthesized, and may be subjected to processing such as hydrogenation or hydroxylation. As a natural product, lecithin, which is an extract / purified product from soybean or egg yolk, is preferable because it is easy to obtain a commercial product. More preferable phospholipids are phospholipids that have been hydrogenated or hydroxylated from the viewpoint of improving the stability of the emulsion, and preferably include hydrogenated soybean lecithin and hydrogenated egg yolk lecithin.

  The content of phosphatidylcholine in the phospholipid can be analyzed by a method using thin layer chromatography (TLC), high performance liquid chromatography (HPLC), Iatroscan (manufactured by Yatron) or the like. For example, an organic solvent containing phospholipid described in JP-A-2001-186898 is spotted on TLC, developed with chloroform: methanol: acetic acid = 65: 25: 10, sprayed with 50 wt% ethanol sulfate, and after heating A method of analyzing phospholipids with a densitometer is mentioned. In addition to the above method, any method may be used as long as it can measure and calculate the content and content of phosphatidylcholine contained in the phospholipid.

  Examples of phospholipids containing 60% by mass or more of phosphatidylcholine include coatsome NC-21 (hydrogenated soybean lecithin; manufactured by NOF Corporation), resinol S-10E, and resinol S-10EX (hydrogenated soybean lecithin; Nikko Chemicals). Manufactured).

  A phospholipid may be used independently and may be used in mixture of 2 or more types. The content of the component (A) is preferably 0.001 to 5% by mass, more preferably 0.01 to 2% by mass, more preferably 0.01 to 2% by mass, based on the total amount of the gel external preparation for skin, in terms of stability and sensory characteristics. Preferably it is 0.1-1 mass%.

The (B) carboxyvinyl polymer, acrylic acid / alkyl methacrylate copolymer and salts thereof used in the present invention are general-purpose raw materials for cosmetics and are used as thickening / gelling agents.
The carboxyvinyl polymer is a water-soluble vinyl polymer having a carboxyl group, and examples thereof include polyacrylic acid. The base residue for neutralizing the carboxyvinyl polymer to form a salt and forming a structure is preferably an alkali metal salt such as sodium salt or potassium salt, or an alkaline earth metal salt such as calcium or magnesium. It can be illustrated. The content of such base residues is preferably adjusted to 2 equivalents or less, more preferably 1.5 equivalents or less with respect to the carboxyvinyl polymer. This is because a gel with high salt resistance is formed by taking such a form.
Specifically, carbopol 940, carbopol 941, carbopol 980, carbopol 981 (Noveon Inc.), Shintalen (Wako Pure Chemical Industries, Ltd.), AQPEC HV-501E (Sumitomo Seika Co., Ltd.) Commercial products such as can be used.

  The acrylic acid / alkyl methacrylate copolymer is a copolymer of acrylic acid and an alkyl methacrylate (preferably an alkyl group having 8 to 30 carbon atoms). For example, commercially available products such as Pemlen TR-1, Pemlen TR-2, Carbopol EDT2020, Carbopol 1382 (Noveon Inc.) can be used.

  Among these, it is preferable to use a carboxyvinyl polymer and / or a salt thereof and an acrylic acid / alkyl methacrylate copolymer in combination from the viewpoint of storage stability and skin familiarity. The mass content ratio between the carboxyvinyl polymer and the acrylic acid / alkyl methacrylate copolymer is preferably 5: 1 to 1: 1, more preferably 3: 1 to 3: 2.

  Although content of (B) component of this invention is not specifically limited, From the point of storage stability, 0.1-1 mass% is preferable with respect to gel-form skin external preparation total amount, More preferably Is 0.2 to 0.8 mass%, more preferably 0.3 to 0.6 mass%.

  The fatty acid ester of (C) cholesterol or phytosterol used in the present invention is an ester of a sterol compound obtained from animal oils and fats, vegetable oils and fats, oleic acid, palmitooleic acid, palmitic acid, stearic acid, behenic acid, 2-ethyl Preferred examples include esters with saturated or unsaturated fatty acids having 8 to 22 carbon atoms such as hexanoic acid, capric acid and lauric acid. An esterified product with a mixture of fatty acids obtained by hydrolyzing natural vegetable oils and animal fats can also be used. For example, fatty acids obtained by decomposing natural fats and oils such as olive oil, avocado oil, sesame oil, and rice germ oil can be obtained in the form of a mixture or by purification to obtain these esterified products.

Specific examples of the cholesterol fatty acid ester include cholesteryl oleate, dihydrocholesteryl oleate, cholesteryl nonanoate, cholesteryl isostearate, dihydrocholesteryl isostearate, macadamia nut fatty acid cholesteryl, lanolin fatty acid cholesteryl, cholesteryl ricinoleate, and the like.
Examples of phytosterol derivatives include phytosteryl oleate, dihydrophytosteryl oleate, phytosteryl nonanoate, phytosteryl isostearate, dihydrophytosteryl isostearate, macadamia nut fatty acid phytosteryl, lanolin fatty acid phytosteryl, and phytosteryl ricinoleate. 1 type, or 2 or more types can be used.
Of these, preferred are macadamia nut fatty acid cholesteryl, lanolin fatty acid cholesteryl, macadamia nut fatty acid phytosteryl, and lanolin fatty acid phytosteryl, more preferred are macadamia nut fatty acid phytosteryl and lanolin fatty acid phytosteryl, and more preferred are macadamia nut fatty acid phytosteryl.

  These components are generally commercially available, and examples thereof include YOFCO CLE series (lanolin fatty acid cholesteryl), YOFCO MAC (macadamia nut fatty acid cholesteryl), YOFCO MAS (macadamia nut fatty acid phytosteryl) and the like (all manufactured by Nippon Seika Co., Ltd.).

  Although content of (C) component of this invention is not specifically limited, 0.01-7 mass% is preferable with respect to the gel-form skin external preparation total amount from the point of the persistence of moisture retention, More Preferably it is 0.1-5 mass%, More preferably, it is 0.1-3 mass%.

  The mass ratio [(B) / (C)] of the component (B) and the component (C) is preferably 0.1 to 8, more preferably 0.3 to 3, and still more preferably 0.3 to When used in the range of 0.8, the sticky feeling is further reduced, and the durability of the moisturizing feeling and the storage stability are excellent.

  Examples of (D) the saturated monohydric alcohol having 1 to 3 carbon atoms used in the present invention include methyl alcohol, ethyl alcohol, propyl alcohol, isopropyl alcohol, and the like, preferably ethyl alcohol.

  Although content of (D) component of this invention is not specifically limited, From the point of a refreshing feeling at the time of application | coating, and the point of storage stability, it is 1 to the gel-form skin external preparation total amount. 15 mass% is preferable, More preferably, it is 2-10 mass%, More preferably, it is 2-8 mass%.

  In the present invention, in addition to the component (C), (E) an oil having a melting point of 28 to 52 ° C. under 1 atm is preferably used in combination in order to improve skin conformance, increase film strength, and improve moisturizing feeling. . An oil having a melting point in the range of 28 to 52 ° C. at 1 atm is an oil showing a paste (semi-solid) at 25 ° C. A preferable melting point is 30 to 45 ° C, more preferably 35 to 40 ° C. In addition, the measuring method of melting | fusing point is based on the 3rd method as described in a quasi-drug raw material specification (2006), a general test method, and a melting | fusing point measuring method.

  As an oil agent having a melting point of 28 to 52 ° C. under 1 atm, specifically, shea butter, lanolin, trilanolin fatty acid glyceryl, soft lanolin fatty acid, petrolatum, dipentaerythritol fatty acid ester (such as dipentaerythritol hexaoxystearate) , Isostearic acid hydrogenated castor oil, monohydroxystearic acid hydrogenated castor oil, tri (capryl / caprin / myristin / stearic acid) glyceride, myristyl lactate and the like. Of these, shea butter, isostearic acid hydrogenated castor oil, monohydroxystearic acid hydrogenated castor oil, and more preferably shea fat. These are used alone or in combination of two or more.

  The content of the component (E) of the present invention is not particularly limited, but is preferably 0.01 to 10% by mass with respect to the total amount of the gel-like external preparation for skin, from the viewpoint of durability of moisturizing. Preferably it is 0.1-5 mass%, More preferably, it is 0.1-3 mass%.

  In addition to the above-mentioned components, the gel-like skin external preparation of the present invention includes water; water-soluble dyes; preservatives such as paraben and phenoxyethanol; anionic surfactants such as sodium cetyl sulfate and N-stearoyl-L-glutamate Non-ionic surfactants such as polyhydric alcohol fatty acid esters, polyglycerin fatty acid esters, modified silicones, sucrose fatty acid esters, polyoxyethylene hydrogenated castor oil, polyoxyethylene fatty acid esters; cationic interfaces such as tetraalkylammonium salts Activators: amphoteric surfactants such as betaine, sulfobetaine, and sulfoamino acid types; natural surfactants such as lecithin, ceramide, and cerebroside; antioxidants such as dibutylhydroxytoluene; sodium chloride, magnesium chloride, sodium sulfate , Potassium nitrate, Inorganic salts such as potassium phosphate and sodium phosphate; citric acid, sodium citrate, potassium acetate, sodium oxalate, sodium aspartate, sodium lactate, carnitine salt, gamma aminobutyric acid, lipoic acid and other organic acid salts; hydrochloric acid Salts such as ethanolamine, ammonium nitrate, arginine hydrochloride and the like; Chelating agents such as edetic acid; Neutralizing agents such as potassium hydroxide, diisopropanolamine and triethanolamine; Biopolymers such as collagen; Placenta extract; Hydroxymethoxybenzophenone sulfone UV absorbers such as acid salts; oil-soluble vitamin C derivatives such as ascorbyl palmitate, ascorbyl stearate and ascorbyl tetraisostearate; polysaccharides extracted from xanthan gum, beta glucan, oats, white jellyfish, etc. Nan and alginate, those extracted from seaweeds such as agar, does not but water-soluble polymers such as such as pectin are mentioned as being limited thereto.

  For the gel-like skin external preparation of the present invention, an extract of a plant, seaweed or fungus can be used, for example, artichoke, eye, arnica, aloe, altea, ashitaba, acerola, apricot, almond, amateur, akebi, anise, Avocado, Ginseng, Nettle, Strawberry, Fennel, Turmeric, Prickly Pear, Oolong Tea, Usenia Oy, Ages, Echinacea, Oat, Emperor, Edelweiss, Dutch Mustard, Aubergine, Ogon, Ouren, Greater Cranberry, Orange Hypericum, Leaf Cassis, valerian, persimmon, fire thorn, chamomile, cam cam, carrot, oakworm, oats, licorice, cucumber, kyounin, kiwi, kina, kiraya, kizuta, gabba tea, mallet, clara, kumazasa, mulberry, Lumi, Grapefruit, Gentian Ginger, Gentiana, Ghetto, Kohiratambutsu, Burdock, Comfrey, Wheat Germ, Cherry, Salmon, Salvia, Hawthorn, Saishin, Saitai, Sanshi, Shimosukeso, Jujuyaku, Shichigenge, Shobu, Ginger, Shikon, Shiso, Shiraba, Peonies, Giants, Seekers, Simon, Horsetails, Star Fruits, Mallows, Sensuo, Hawthorn, Prunus Kizuta, Pears, White Willow, Sage, Assembly, Soybean, Daidai, Thyme, Tachibana, Tachikaku, Tamarind, Tea, Clove, Chimpi, persimmon, dokudami, touki, tonin, spruce, tomato, tokisenka, rattan tea, tormentilla, corn, neem, nigahakka, elderberry, garlic, nin , Wild rose, papuames, hibiscus, parsley, banana, rose, pearl barley, hachiwame, pecan nut, cypress, hyssop, himalayan raspberry, peafowl, sandalwood, bilberry, loquat, prunes, grapes, chrysanthemum, chrysanthemum, peppermint, peppermint , Safflower, loofah, hera plantain, white genepi, cypress, linden tree, button bowfowl, button, hop, jojoba, quince, maika, maronier, pine, mandarin orange, melamine, melissa, pine evening primrose, peach, maple, cornflower, cypress Lily, persimmon, yokuinin, mugwort, orchid, lime, lavender lettuce, apple, ryukyu mugwort, rooibos, forsythia, lemon, lemon balm, rosehip, rosemary, green algae , Red algae, brown algae, broomfish, shiitake mushrooms, mushrooms, Sarno mushrooms, white jellyfish, litchi, cordyceps, yeast, lactic acid bacteria, rhizobial whole plants, leaves, stems, roots, fruits, seeds, flowers, fruit bodies, body to water, Or it is an extract extracted with organic solvents, such as glycerol, propylene glycol, ethanol, butylene glycol, or its liquid mixture. Chlorophyll is also a plant extract. In addition, lactic acid bacteria and yeast culture solutions using raw milk, fruit juice, synthetic medium, and semi-synthetic medium can be used regardless of whether or not the cells are removed.

  There is no restriction | limiting in particular as a use of the gel-form skin external preparation of this invention, It can use suitably for cosmetics, a pharmaceutical, a quasi-drug, etc. Specifically, for external use such as facial cleansers, cleansing cosmetics, lotions, emulsions, beauty creams, base cosmetics, sunscreen cosmetics, packs, massage cosmetics and other skin cosmetics, ointments containing various drugs, creams, etc. It can be suitably used as a medicine. In particular, the gel-like skin external preparation of the present invention is preferably used as a skin external preparation of the type that is retained on the skin without being washed away, because of its excellent moisturizing feeling.

Preferred embodiments of the present invention are shown below.
[1] A gel-like external preparation for skin containing the following components (A) to (D).
(A) Phospholipid (B) carboxyvinyl polymer, acrylic acid / alkyl methacrylate copolymer, and one or more selected from these salts (C) Cholesterol or phytosterol fatty acid ester (D) 1 carbon number To 3 saturated monohydric alcohol [2] The content mass ratio [(B) / (C)] of the component (B) and the component (C) is preferably 0.1 to 8, more preferably 0.3 to 3, The gel-form external preparation for skin as described in [1] which is 0.3-0.8 more preferably.
[3] Gel skin external application as described in [1] or [2], wherein the component (A) is a phospholipid having a phosphatidylcholine content of 60% by mass or more, preferably 65% by mass or more, more preferably 70% by mass or more. Agent.
[4] Gel skin external application according to any one of [1] to [3], wherein the component (A) is selected from soybean or egg yolk-derived lecithin and a hydrogenated product of soybean or egg yolk-derived lecithin. Agent.
[5] The content of the component (A) is 0.001 to 5% by mass, preferably 0.01 to 2% by mass, more preferably 0.1 to 1% by mass with respect to the total amount of the gel external preparation for skin. The gel-like skin external preparation according to any one of [1] to [4].
[6] The gel skin external preparation according to any one of [1] to [5], wherein the component (B) contains a carboxyvinyl polymer and an acrylic acid / alkyl methacrylate copolymer.
[7] The component (B) contains a carboxyvinyl polymer and an acrylic acid / alkyl methacrylate copolymer in a mass ratio of 5: 1 to 1: 1, preferably 3: 1 to 3: 2. [1] To [6] The gel external preparation for skin according to any one of [6].
[8] The content of the component (B) is 0.1 to 1% by mass, preferably 0.2 to 0.8% by mass, more preferably 0.3 to 0%, based on the total amount of the gel external preparation for skin. The gel external preparation for skin according to any one of [1] to [7], which is 6% by mass.
[9] The component (C) is cholesteryl oleate, dihydrocholesteryl oleate, cholesteryl nonanoate, cholesteryl isostearate, dihydrocholesteryl isostearate, macadamia nut fatty acid cholesteryl, lanolin fatty acid cholesteryl, ricinoleate cholesteryl, phytosteryl oleate, dihydrooleate One or more selected from phytosteryl, phytosteryl nonanoate, phytosteryl isostearate, dihydrophytosteryl isostearate, macadamia nut fatty acid phytosteryl, lanolin fatty acid phytosteryl, and phytosteryl ricinoleate [1] to [8] The gel external preparation for skin according to any one of the above.
[10] The component (C) is one or more selected from macadamia nut fatty acid cholesteryl, lanolin fatty acid cholesteryl, macadamia nut fatty acid phytosteryl, and lanolin fatty acid phytosteryl, according to any one of [1] to [9] Gel skin external preparation.
[11] The content of the component (C) is 0.01 to 7% by mass, preferably 0.1 to 5% by mass, and more preferably 0.1 to 3% by mass, based on the total amount of the gel external preparation for skin. The gel-form external preparation for skin according to any one of [1] to [10].
[12] The gel skin external preparation according to any one of [1] to [11], wherein the component (D) is ethanol.
[13] The content of the component (D) is 1 to 15% by mass, preferably 2 to 10% by mass, more preferably 2 to 8% by mass, based on the total amount of the gel external preparation for skin use. [12] The gel-form skin external preparation in any one of [12].
[14] The gel-like external preparation for skin according to any one of [1] to [13], further comprising (E) an oil having a melting point of 28 to 52 ° C. other than the component (C).
[15] The gel skin external preparation according to [14], wherein the component (E) is one or more selected from shea fat, isostearic acid hydrogenated castor oil, and monohydroxystearic acid hydrogenated castor oil.
[16] The gel-like external preparation for skin according to any one of [1] to [15], wherein the viscosity is 15000 to 50000 mPa · s.

  EXAMPLES Next, although an Example demonstrates this invention still in detail, this invention is not limited to these.

Examples 1-11, Comparative Examples 1-4
According to the formulation shown in Table 1, a gel-like external preparation for skin was prepared. Using these, the following (1) sensory test and (2) storage stability test were carried out and evaluated. The results are also shown in Table 1.

(1) Sensory test For female panelists (10 persons), the gel-type skin external preparations shown in the examples and comparative examples were used, and “stickiness when applied”, “skin familiarity”, “film feeling”, “moisturizing” Questionnaire was conducted on the four items of “Sustainability” and the evaluation was performed based on the following evaluation criteria.

(Evaluation criteria)
Stickiness at the time of application 5: None 4: Almost none 3: Neither of them 2: Somewhat 1: There is

Skin familiarity 5: Good 4: Slightly good 3: Not good 2: Slightly bad 1: Bad

Feeling of film 5: Flexible 4: Slightly flexible 3: Neither can be said 2: Slightly hard 1: Hard

Persistence of moisturizing 5: Persistence 4: Slightly persistent 3: Neither can be said 2: Slightly non-persistent 1: Not persistent (Criteria)
◎: Average point is 4.0 or more ○: Average point is 3.0 or more and less than 4.0 △: Average point is 2.0 or more and less than 3.0 ×: Average point is less than 2.0

(2) Storage stability test The gel skin external preparation shown in Table 1 was put in a glass bottle and stored in a thermostatic bath at 60 ° C for 1 month. Based on the state immediately after preparation, the change in appearance after one month was determined from the following criteria.
(Evaluation criteria)
◎: No change ○: Some change in viscosity is seen △: Clear change in viscosity is seen ×: Separated

(Production method)
A. Ingredients 1, 5, 6, 9-12 are uniformly mixed and dissolved at 80 ° C.
B. Ingredients 15 and 16 are uniformly mixed and dissolved at 80 ° C.
C. B was added to A and stirred, then components 2, 3, 7, 13, and 14 were added and stirred, and a gel was obtained after cooling.

  It is clear that the gel-like external preparation for skin shown in the examples is superior in the feeling of stickiness, the goodness of skin familiarity, the softness of the film feeling, and the moisturizing property as compared with the comparative example. In addition, the viscosity after manufacture of the gel-form skin external preparation shown in Examples 1-11 is 20000-40000 mPa.s. It is in the range of s.

  The formulation example of the gel skin external preparation of this invention is given to the following. All of them are expected to be gel-type skin external preparations that are excellent in feeling of use (no stickiness, softness to skin, and softness of film feeling), and have good moisture retention and storage stability.

(Formulation example 1: Gel cream for moisturizing)
Component Content (mass%)
1. Hydrogenated soybean phospholipid (Note 1) 0.5
2. Macadamia nut oil 1.0
3. Macadamia nut fatty acid phytosteryl (Note 2) 2.0
4). Shea fat 1.0
5. Cholesterol 0.2
6). Squalane 3.0
7). Dipropylene glycol 7.0
8). Acrylic acid / alkyl methacrylate copolymer (Note 3) 0.2
9. Carboxyvinyl polymer (Note 4) 0.3
10. Ethanol 5.0
11. Dipotassium glycyrrhizinate 0.01
12 Edetic acid disodium 0.01
13. Potassium hydroxide 0.2
14 Sodium hyaluronate (Note 5) 0.01
15. Rose water 0.01
16. Carrot extract 0.01
17. Water-soluble collagen (Note 6) 0.01
18. Star fruit leaf extract 0.01
19. Licorice leaf extract 0.01
20. Senkyu Extract 0.01
21. Fermented soymilk extract 0.01
22. Yokuinin extract 0.01
23. Nicotinamide 0.01
24. Acetylglucosamine 0.01
25. Coenzyme Q10 0.01
26. Thioctic acid 0.01
27. Phenoxyethanol appropriate amount28. Purified water remaining amount Note 1: Cotesome NC-21 (manufactured by NOF Corporation)
Note 2: YOFCO MAS (manufactured by Nippon Seika)
Note 3: PEMULEN TR-1 (Noveon)
Note 4: Shintalen K (manufactured by Wako Pure Chemical Industries)
Note 5: Hyaluronic acid FCH-SU (Kikkoman Biochemifa)
Note 6: Solu-Mar Native (Arch Personal Care Products LP)

(Formulation example 2: Moisturizing gel cream)
Component Content (mass%)
1. Hydrogenated soybean phospholipid (Note 1) 0.5
2. Macadamia nut oil 1.0
3. Lanolin Fatty Acid Cholesteryl (Note 7) 2.0
4). Shea fat 1.0
5. Cholesterol 0.2
6). Squalane 3.0
7). Isostearic acid 0.1
8). Nicotinic acid dl-α-tocopherol 0.01
9. Glycerin 3.0
10. Sorbitol 2.0
11.1,3-butylene glycol 10.0
12 Polyethylene glycol 4000 1.0
13. Acrylic acid / alkyl methacrylate copolymer (Note 3) 0.2
14 Carboxyvinyl polymer (Note 4) 0.3
15. Ethanol 5.0
16. Dipotassium glycyrrhizinate 0.01
17. Edetate trisodium 0.03
18. Potassium hydroxide 0.2
19. Xanthan gum 0.1
20. Arbutin 1.0
21. Hydrolyzed collagen (Note 6) 0.01
22. Tea extract 0.01
23. Tea fruit extract 0.01
24. Prune extract 0.01
25. Fragrance 0.1
26. Methyl paraben appropriate amount 27. Purified water remaining amount Note 7: YOFCO CLE-S (Nippon Seika Co., Ltd.)

  In addition, the thing of the following fragrance | flavor prescription was used for the fragrance | flavor in the formulation example.

Claims (4)

A gel-like external preparation for skin containing the following components (A) to (D).
(A) Phospholipid (B) carboxyvinyl polymer, acrylic acid / alkyl methacrylate copolymer, and one or more selected from these salts (C) Cholesterol or phytosterol fatty acid ester (D) 1 carbon number ~ 3 saturated monohydric alcohol   The gel skin external preparation according to claim 1, wherein the component (C) is one or more selected from macadamia nut fatty acid cholesteryl, lanolin fatty acid cholesteryl, macadamia nut fatty acid phytosteryl and lanolin fatty acid phytosteryl.   The gel-form skin external preparation of Claim 1 or 2 whose containing mass ratio [(B) / (C)] of (B) component and (C) component is 0.1-8.   The gel-like skin external preparation according to any one of claims 1 to 3, wherein the component (B) contains a carboxyvinyl polymer and an acrylic acid / alkyl methacrylate copolymer.