JPH11506739A5 - - Google Patents

Info

Publication number
JPH11506739A5
JPH11506739A5 JP1997500833A JP50083397A JPH11506739A5 JP H11506739 A5 JPH11506739 A5 JP H11506739A5 JP 1997500833 A JP1997500833 A JP 1997500833A JP 50083397 A JP50083397 A JP 50083397A JP H11506739 A5 JPH11506739 A5 JP H11506739A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997500833A
Other languages
English (en)
Japanese (ja)
Other versions
JP3962430B2 (ja
JPH11506739A (ja
Filing date
Publication date
Priority claimed from US08/484,545 external-priority patent/US5631347A/en
Application filed filed Critical
Publication of JPH11506739A publication Critical patent/JPH11506739A/ja
Publication of JPH11506739A5 publication Critical patent/JPH11506739A5/ja
Application granted granted Critical
Publication of JP3962430B2 publication Critical patent/JP3962430B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50083397A 1995-06-07 1996-06-04 脂肪酸アシル化蛋白質のゲル化削減法 Expired - Fee Related JP3962430B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/484,545 US5631347A (en) 1995-06-07 1995-06-07 Reducing gelation of a fatty acid-acylated protein
US08/484,545 1995-06-07
PCT/US1996/007965 WO1996040188A1 (en) 1995-06-07 1996-06-04 Reducing gelation of a fatty acid-acylated protein

Publications (3)

Publication Number Publication Date
JPH11506739A JPH11506739A (ja) 1999-06-15
JPH11506739A5 true JPH11506739A5 (https=) 2004-07-22
JP3962430B2 JP3962430B2 (ja) 2007-08-22

Family

ID=23924602

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50083397A Expired - Fee Related JP3962430B2 (ja) 1995-06-07 1996-06-04 脂肪酸アシル化蛋白質のゲル化削減法

Country Status (10)

Country Link
US (1) US5631347A (https=)
EP (1) EP0747390B1 (https=)
JP (1) JP3962430B2 (https=)
AT (1) ATE264867T1 (https=)
AU (1) AU5951596A (https=)
CA (1) CA2223531A1 (https=)
DE (1) DE69632224T2 (https=)
DK (1) DK0747390T3 (https=)
ES (1) ES2218569T3 (https=)
WO (1) WO1996040188A1 (https=)

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US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US6858580B2 (en) * 2001-06-04 2005-02-22 Nobex Corporation Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6835802B2 (en) * 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
US6713452B2 (en) * 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828297B2 (en) * 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
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US7196059B2 (en) * 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US6913903B2 (en) * 2001-09-07 2005-07-05 Nobex Corporation Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
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US7166571B2 (en) * 2001-09-07 2007-01-23 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
AU2003236521A1 (en) 2002-06-13 2003-12-31 Nobex Corporation Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
PL1633391T3 (pl) 2003-06-03 2012-03-30 Novo Nordisk As Stabilizowane farmaceutycznie kompozycje peptydowe
KR101308912B1 (ko) 2003-06-03 2013-09-23 노보 노르디스크 에이/에스 안정화된 약학적 펩티드 조성물
DK3300721T4 (da) 2003-11-20 2025-03-03 Novo Nordisk As Propylenglycol-holdige peptidformuleringer hvilke er optimale til fremstilling og til anvendelse i injektionsindretninger
RU2527893C2 (ru) * 2004-07-19 2014-09-10 Биокон Лимитед Инсулин-олигомерные конъюгаты, их препараты и применения
PL1789434T3 (pl) 2004-08-31 2014-07-31 Novo Nordisk As Zastosowanie tris(hydroksymetylo)aminometanu do stabilizacji peptydów, polipeptydów i białek
MX2007005521A (es) 2004-11-12 2007-05-18 Novo Nordisk As Formulaciones estables de peptidos insulinotropicos.
BRPI0710503A2 (pt) * 2006-04-07 2011-08-16 Merrion Res Iii Ltd uso de uma composição farmacêutica, composição farmacêutica, e, forma de dosagem oral
JP2009539862A (ja) * 2006-06-09 2009-11-19 メリオン リサーチ Ｉｉｉ リミテッド 強化剤を含む固体経口投与剤形
RU2453332C2 (ru) * 2007-10-16 2012-06-20 Байокон Лимитид Твердая фармацевтическая композиция (варианты) и способ контроля концентрации глюкозы с ее помощью, способ получения твердой фармацевтической композиции (варианты), таблетка (варианты) и способ получения амфорных частиц
RU2517135C2 (ru) * 2008-05-07 2014-05-27 Меррион Рисерч Iii Лимитед Композиции пептидов и способы их получения
CA2751854A1 (en) * 2009-02-25 2010-09-02 Merrion Research Iii Limited Composition and drug delivery of bisphosphonates
WO2011064316A2 (en) 2009-11-25 2011-06-03 Paolo Botti Mucosal delivery of peptides
US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
US9089484B2 (en) * 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
KR20140026354A (ko) 2011-01-07 2014-03-05 메리온 리서치 Ⅲ 리미티드 경구 투여용 철의 제약 조성물
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
JP7211704B2 (ja) 2015-01-29 2023-01-24 ノヴォ ノルディスク アー／エス Ｇｌｐ－１アゴニスト及び腸溶コーティングを含む錠剤
WO2018157150A1 (en) 2017-02-27 2018-08-30 Duke University In vivo protein n-acylation
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
JP7761567B2 (ja) 2020-02-18 2025-10-28 ノヴォ ノルディスク アー／エス 医薬製剤

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