JPH10507632A - 母体からの胎児血液の濃縮 - Google Patents

母体からの胎児血液の濃縮

Info

Publication number
JPH10507632A
JPH10507632A JP8511058A JP51105895A JPH10507632A JP H10507632 A JPH10507632 A JP H10507632A JP 8511058 A JP8511058 A JP 8511058A JP 51105895 A JP51105895 A JP 51105895A JP H10507632 A JPH10507632 A JP H10507632A
Authority
JP
Japan
Prior art keywords
cells
fetal
dna
suspension
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8511058A
Other languages
English (en)
Japanese (ja)
Inventor
ブッシュ，ユルゲン
ラトブルフ，アンドレアス
ミルテニー，ステファン
ホルツ，イルゲン
Original Assignee
ミルテニー バイオテック，インコーポレイティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ミルテニー バイオテック，インコーポレイティド filed Critical ミルテニー バイオテック，インコーポレイティド
Publication of JPH10507632A publication Critical patent/JPH10507632A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP8511058A 1994-09-20 1995-09-19 母体からの胎児血液の濃縮 Pending JPH10507632A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30922994A 1994-09-20 1994-09-20
US08/309,229 1994-09-20
PCT/US1995/011971 WO1996009409A1 (fr) 1994-09-20 1995-09-19 Enrichissement de cellules f×tales, a partir du sang maternel

Publications (1)

Publication Number Publication Date
JPH10507632A true JPH10507632A (ja) 1998-07-28

Family

ID=23197274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8511058A Pending JPH10507632A (ja) 1994-09-20 1995-09-19 母体からの胎児血液の濃縮

Country Status (5)

Country Link
EP (1) EP0778899A4 (fr)
JP (1) JPH10507632A (fr)
AU (1) AU691040B2 (fr)
CA (1) CA2200294A1 (fr)
WO (1) WO1996009409A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013531259A (ja) * 2010-07-21 2013-08-01 ディアガスト 赤血球の血液型判定および表現型判定における抗体／抗原複合体の実証のための磁気的免疫診断法およびキット
JP2015501646A (ja) * 2011-12-17 2015-01-19 深▲せん▼華大基因医学有限公司 ゲノムの異常の有無を判断する方法及びシステム

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294964B1 (it) * 1996-07-12 1999-04-23 Domenico Valerio Isolamento e cultura di cellule fetali dal sangue periferico materno
DE69709377T2 (de) * 1996-09-04 2002-08-14 Scandinavian Micro Biodevices Mikrofliesssystem für die teilchenanalyse und trennung
FR2758884B1 (fr) * 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
CA2283416A1 (fr) 1997-03-08 1998-09-17 The University Of Dundee Procedes de diagnostic prenatal
GB0009179D0 (en) * 2000-04-13 2000-05-31 Imp College Innovations Ltd Non-invasive prenatal diagnosis
GB0616045D0 (en) * 2006-08-11 2006-09-20 Univ Bristol Blood cell separation
GB2447255A (en) * 2007-03-02 2008-09-10 Oncoprobe Ltd Preparation of enriched target cell samples for use in a chemosensitivity assay
EP2955521A1 (fr) * 2014-06-11 2015-12-16 Centre Hospitalier Universitaire Vaudois (CHUV) Procédés pour séparer des cellules
CN109718880A (zh) * 2019-02-20 2019-05-07 广州睿辰生物科技有限公司 基于双抗法分选胎儿有核红细胞额定微流控芯片及其分选方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4230685A (en) * 1979-02-28 1980-10-28 Northwestern University Method of magnetic separation of cells and the like, and microspheres for use therein
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
WO1991016452A1 (fr) * 1990-04-23 1991-10-31 Cellpro Incorporated Procede servant a enrichir des cellules f×tales avec du sang maternel

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013531259A (ja) * 2010-07-21 2013-08-01 ディアガスト 赤血球の血液型判定および表現型判定における抗体／抗原複合体の実証のための磁気的免疫診断法およびキット
JP2015501646A (ja) * 2011-12-17 2015-01-19 深▲せん▼華大基因医学有限公司 ゲノムの異常の有無を判断する方法及びシステム

Also Published As

Publication number Publication date
CA2200294A1 (fr) 1996-03-28
EP0778899A1 (fr) 1997-06-18
WO1996009409A1 (fr) 1996-03-28
AU691040B2 (en) 1998-05-07
EP0778899A4 (fr) 2001-08-29
AU3593595A (en) 1996-04-09

Similar Documents

Publication Publication Date Title
EP0500727B1 (fr) Procede non envahissant d'isolation et de detection d'adn f tal
US5714325A (en) Prenatal diagnosis by isolation of fetal granulocytes from maternal blood
JP6310540B2 (ja) 母体血液中の胎児細胞の濃縮及び同定及びこれに使用するリガンド
JP2965699B2 (ja) 胎児細胞回収法
US7785898B2 (en) Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
US9885032B2 (en) Multisort cell separation method
US20090081689A1 (en) Reagents and methods to enrich rare cells from body fluids
US20140141997A1 (en) Foetal nucleated red blood cell detection
AU691040B2 (en) Enrichment of fetal cells from maternal blood
Prieto et al. Optimization of nucleated red blood cell (NRBC) recovery from maternal blood collected using both layers of a double density gradient
JPH11502106A (ja) 少数細胞集団を濃縮する方法
KR20230114327A (ko) 태아 세포의 단리, 검출 및 분석을 위한 조성물 및방법
Pongsritasana et al. Isolation of fetal nucleated red blood cell from maternal blood using immunomagnetic beads for prenatal diagnosis
WO2023104773A1 (fr) Isolement et diagnostic de cellules foetales
AU7232700A (en) Non-invasive method for isolation and detection of fetal DNA
AU7735201A (en) Fetal cell recovery method
AU9718698A (en) Prenatal diagnosis by isolation of fetal granulocytes from maternal blood