JPH10226787A - Antioxidant - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an antioxidant which can be safely applied to the skin, has high antioxidant action and can inhibit the oxidation of oils in food or cosmetics, the oxidation on the skin and the oxidation within the body when used in edible use by using a solvent extract of cumin. SOLUTION: Cumin, an annual herb of the family Cuminum cyminum L., is extracted with water or a hydrophilic organic solvent such as ethanol, methanol, acetone, glycerol, 1,3-bulylene glycol or propylene glycol or a mixed solvent thereof under heating or at room temperature to obtain an extract. The extract is optionally lyophilized to obtain a powdery product. About 1wt.% or below extract or powdery product is added to a starting material for a cosmetic, a starting material for food, a drink or the like to effectively prevent its oxidation. Depending on the form of use, it may be further adjusted by adding an activator, a humectant, a drug or the like.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an antioxidant having a high antioxidant activity and a high safety, which is incorporated in foods, cosmetics and pharmaceuticals.

[0002]

2. Description of the Related Art Cumin is an annual herbaceous plant of the Apiaceae family, native to Egypt, Turkistan and the eastern Mediterranean, and currently widely cultivated from China to India and the Mediterranean coast. And the steam distilled oil is used as a spice and as a fragrance.

[0003] On the other hand, various substances having an antioxidant action that can be used as a raw material of cosmetics are known, but synthetic products have no guarantee of safety when applied to human skin for a long time. , Use is being restricted. On the other hand, many natural products have weak antioxidant effects. However, it is a natural product from the aspect of safety for human skin, and it has been eaten by humans for many years,
There is a need for a substance that is guaranteed in terms of safety, has a strong antioxidant effect, and has other effects on the skin.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to provide an antioxidant which is safe when applied to the skin, has a large antioxidant action and is excellent in safety.

[0005]

Means for Solving the Problems In order to solve the above-mentioned problems, the present inventors have screened and examined plants which have been used for food for many years and which have been confirmed to be safe for the human body. I considered something. As a result, they found that cumin was very effective as a food material, cosmetic material, or quasi-drug.

That is, the present invention is an antioxidant comprising a solvent extract of cumin. The antioxidant action can prevent the oxidation of cosmetics and foods themselves, and can prevent oxidation in the body by digestion and absorption of cosmetics on the skin and foods.

[0007] As a method of using cumin, extraction is carried out with water or a hydrophilic organic solvent such as ethanol, methanol or acetone. However, it is a matter of course that extraction with water, ethanol, or a mixed solvent thereof is preferable because the cosmetic raw material is extracted. Also, in some cases,
Polyhydric alcohols such as glycerin, 1,3-butylene glycol and propylene glycol, or a mixture of polyhydric alcohol and water can also be used for the extraction. It is also effective to freeze-dry and use as a powder depending on the method of use.

This substance is used as a raw material for other cosmetics such as liquid oils such as squalane and jojoba oil, solid oils such as beeswax and cetyl alcohol, various activators, humectants such as glycerin and 1,3-butylene glycol and various chemicals. It can be added to adjust cosmetics in various dosage forms. For example, a use form may be considered depending on the purpose, such as a lotion, a cream, an emulsion, a pack, and the like.

[0009]

EXAMPLES An example of an actual use method will be described below, but the present invention is not limited to this example. Production examples of the cumin extract used in the present invention are shown below.

Production Example 1 10% of cumin seeds (dry product) in 50% ethanol 3
After adding 00 ml, the mixture was left for 5 days with occasional stirring. This was filtered, evaporated and freeze-dried.

Production Example 2 300 ml of purified water was added to 10 g of a cumin seed (dry product) and heated for 3 hours. This was allowed to cool, filtered, and lyophilized.

Prescription Example-1 Chocolate (All the following prescription examples are parts by weight) Chocolate 60 Sucrose 10 Cocoa butter 10 Whole milk powder 19 Production Example-1 1

Formulation Example 2 Ground Sausage 93.0 Chicken Egg 6.0 Spice 0.3 Production Example-2 0.7

Formulation Example 3 Healthy Drink (Juice Type) Glucose Liquid Sugar 10.0 Orange Juice 89.5 Production Example-2 0.5

Formulation Example 4 Lotion Olive Oil 0.5 Extract of Production Example 1 0.5 Polyoxyethylene (20E.O) Sorpentane Monostearate 2.0 Polyoxyethylene (60E.O) Hardened Castor Oil 2.0 Ethanol 10.0 1.0% aqueous solution of sodium hyaluronate 5.0 Purified water 80.0

Example-5 Cream A Squalane 20.0 Olive Oil 2.0 Mink Oil 1.0 Jojoba Oil 5.0 Beeswax 5.0 Cetostearyl Alcohol 2.0 Glycerin Monostearate 1.0 Sorbitan Monostearate 2. 0 Extract of Production Example 2 1.0 B Purified water 47.9 Polyoxyethylene (20E.O) sorbitan monostearate 2.0 Polyoxyethylene (60E.O) hydrogenated castor oil 1.0 Glycerin 5.0 1 0.0% aqueous sodium hyaluronate solution 5.0 Methyl parahydroxybenzoate 0.1 A and B were each weighed, heated to 70 ° C., and A was gradually added to B with stirring, and then 30 A with slow stirring.
Cooled to ° C.

Antioxidant Test Antioxidant Test The following test solutions were prepared in 50 ml test tubes with screw caps. Sample 5 mg 2% linoleic acid ethanol solution 10 ml 0.1 M, pH 7.0 phosphate buffer 10 ml Purified water 5 ml

This is left in a constant temperature bath at 50 ° C., shielded from light. The following measurements were made before, after 3 days, after 6 days, and after 8 days before placing this in a thermostat. 0.12 ml of test solution, 12.125 ml of 75% ethanol and 0.125 ml of 30% ammonium thiocyanate were added, stirred, left for 3 minutes, and then added to 0.02 ml.
0.125 ml of a 3.5% HCl aqueous solution of N ferrous chloride was added, stirred, left for 3 minutes, and the absorbance was measured at a wavelength of 500 nm. The cell length was 1 cm, and the control cell was one in which the test solution was replaced with water. Table 1 shows the results.

[0019]

[Table 1]

Use test The face of each of five women was divided into left and right, one was used as an example and the other was used as a comparative example, and used once or more daily.
A questionnaire was given after March. In the comparative examples, various extracts of the production examples were replaced with water from the examples. (Comparative Examples 1 and 2) Table 2 shows the samples used for the test.

[0021]

[Table 2]

Table 3 summarizes the results of the questionnaire as follows. Example is very good 3 Example is considerably better 2 Example is slightly better 1 No difference 0 Comparative example is slightly better -1 Comparative example is much better -2 Comparative example Is much better -3

[0023]

[Table 3]

[0024]

[Effect] Cumin solvent extract has high antioxidant effect, suppresses antioxidant of oil of food and cosmetics, antioxidant on skin, oxidation of body when eaten, antioxidant containing solvent extract of cumin The agent was found to be very effective.

Claims (1)

[Claims] 1. An antioxidant comprising a solvent extract of cumin.