JPH1017450A - Composition for oral cavity - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a composition for oral cavity leaving a pleasing aftertaste, containing Phyllanthus fruit or an extract therefrom as active ingredient. SOLUTION: This composition for oral cavity contains 0.001-5 (esp. 0.01-3)wt.%, on a solid basis, of Phyllanthus emblica L. belonging to the Euphoria family or an extract therefrom as active ingredient. The Phyllantus fruit to be used is in the form of paste, fruit juice or dried product, while the extract therefrom to be used in the form of solvent extract derived from paste, fruit juice, dried product, solvent extract or the residues therefrom. The extraction is conducted at room temperature or higher temperatures for 0.5-24h by adding a polar or nonpolar solvent to the above-mentioned material. This composition can be prepared into toothpaste, tooth wash, mouthwash, ointment for oral cavity, tablets for gargling, etc., affording the refreshing and bracing feel in the oral cavity owing to such constrictive effect as to leave a pleasing aftertaste.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to oral compositions such as dentifrices and mouthwashes.

[0002]

BACKGROUND OF THE INVENTION Since oral compositions such as dentifrices are used in the oral cavity, they need to have a good feeling in use, especially aftertaste after use. Good things are desired.

[0003] The present invention has been made in view of the above circumstances,
An object of the present invention is to provide a composition for oral cavity which shows an excellent tightness in the oral cavity due to an astringent action and has a good aftertaste.

[0004]

Means for Solving the Problems and Embodiments of the Invention As a result of intensive studies to achieve the above object, the present inventor has found that when phyllans fruit or an extract thereof is incorporated into an oral composition, the aftertaste is reduced. The present inventors have found that a refreshing feeling in the oral cavity can be obtained by a good astringent action, and the present invention has been achieved.

That is, phyllansus is a phytolanthus emblica of the family Euphorbiaceae.
mblica L .; In the Chinese name, the plant is called citrus, and the fruit is called Ammaroku. Fruits contain a large amount of vitamin C. In the Yunnan region, fresh or salted food is used for C deficiency and cold. In Southeast Asia, it is used as a folk medicine for diarrhea and gallstones. Japanese Patent Application Laid-Open No. 4-169533 proposes that a filansus fruit decoctioned with water together with yuzu seeds, lily root and tea root is proposed as a medicine and food effective for colds, hay fever, improvement of allergic constitution and bad breath. ing. JP-A-7-138180 discloses a hyaluronidase inhibitory activity in the whole plant of the congener plant Philanthus nuriri, and proposes its application to cosmetics for preventing fine wrinkles and dry skin. However, the application of the phylanthus emblica fruit to oral products has not been proposed, and the phylanthus fruit or its extract is incorporated into the oral composition,
It is a new finding of the present inventors to provide an excellent tightening feeling in the oral cavity by the astringent action and to improve the aftertaste.

[0006] Conventionally, as a crude drug having an astringent action, Asenyaku, Miko, Betelnut, Beetroot, Gotobiko, etc. are known, but when used in a product for oral cavity, a strong bitter taste is produced in the mouth. Although spread and uncomfortable, filansus fruits and their extracts do not have such disadvantages.

Hereinafter, the present invention will be described in more detail. The oral composition of the present invention contains a filans fruit or an extract thereof.

[0008] Here, as the filansus fruit, any of paste, fruit juice and dried matter can be used. In addition, the extract of filansus fruit is a paste, juice, dried product, or an extract obtained by extracting them with a solvent and a raw material selected from the extraction residue, and the extract is collected by extracting with a solvent. Or a step of deoiling and decoloring by steam distillation before or after the extraction step.

In the extraction process, a solvent is added to the above raw materials,
From room temperature to under heating, usually for 0.5 to 24 hours, especially for 1 to 1
It is preferably performed for 0 hours. In particular, when an extract or fruit juice is used as a raw material, extraction is preferably performed by partitioning the extract into two polar and nonpolar solvents.

The solvent used in the extraction may be a polar solvent or a non-polar solvent, and may be a single solvent or a mixed solvent. Specific examples of the solvent include ethyl ether, ethylene chloride, dioxane, acetone, ethanol, methanol, ethyl acetate, propylene glycol,
n-hexane, petroleum ether, ligroin, cyclohexane, carbon tetrachloride, chloroform, dichloromethane,
1,2-Dichloroethane, toluene, benzene, water, acid solutions, alkali solutions, salt solutions, or other aqueous solutions can be used.

[0011] The extraction residue may be subjected to the above-mentioned extraction treatment again if necessary to obtain an extract, which can be combined with the previous extract. In this case, a solvent different from the above solvent can be used as the extraction solvent.

The extract thus obtained can be treated with another solvent, if necessary. The extract obtained finally can be preferably used for an oral composition by evaporating the solvent.

When the phyllans fruit or its extract is used in the oral composition, the amount of the composition is 0.001 to 5% (solid content% by weight, hereinafter the same) of the whole oral composition, especially 0.01%. It is preferable to set it to ３3%. If less than 0.001%, a satisfactory effect may not be exhibited, and 5%
If it exceeds 50, the stability or flavor of the composition may be impaired.

The oral composition of the present invention can be prepared as toothpastes such as toothpaste and liquid toothpaste, mouthwashes, oral ointments, gargle tablets and the like. The components used in ordinary oral compositions can be used depending on the conditions and the like, and the added amounts of these components can be made as usual as long as the effects of the present invention are not impaired.

In the case of dentifrices, for example, abrasives, binders,
Thickeners, surfactants, sweeteners, preservatives, flavors, coloring agents,
Various active ingredients and the like can be blended, and these ingredients can be mixed with water for production.

As the abrasive, silica abrasives such as precipitated silica, silica gel, aluminosilicate and zirconosilicate, dibasic calcium phosphate dihydrate and anhydrate, calcium pyrophosphate, calcium carbonate,
Aluminum hydroxide, alumina, magnesium carbonate, tertiary magnesium phosphate, zeolite, zirconium silicate, synthetic resin-based abrasives and the like are preferably used.

As the binder, sodium carboxymethylcellulose, hydroxyethylcellulose, carrageenan, sodium alginate, xanthan gum, carbopol, guar gum, montmorillonite, gelatin and the like are preferably used.

As the thickener, glycerin, sorbitol, propylene glycol, polyethylene glycol,
Xylit, maltit, lactit, and the like are preferably used.

As the surfactant, an anionic surfactant, a cationic surfactant, a nonionic surfactant and the like can be blended, and specific examples thereof include sodium lauryl sulfate, sodium α-olefin sulfonate, and N-acyl sulfonate. Cosinate, N-acyl glutamate, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, N-acyl taurate, sucrose fatty acid ester, alkylol amide, polyoxyethylene hydrogenated castor oil, polyglycerin Fatty acid esters, pluronics, polyoxyethylene sorbitan monostearate and the like are preferably used.

As sweeteners, sodium saccharin,
Stevioside, stevia extract, paramethoxycinnamic aldehyde, neohesperidyl hydrochalcone,
And perillartin.

Examples of the preservative include paraoxybenzoate, sodium benzoate and the like.

Suitable fragrances include terpenes such as l-menthol, carvone, anethole, limonene and the like, and derivatives thereof.

As the coloring agent, Blue No. 1, Yellow No. 4, titanium dioxide and the like are preferable.

Various active ingredients include sodium fluoride, potassium fluoride, ammonium fluoride, and primary fluoride.
Fluorides such as tin and sodium monofluorophosphate,
Water-soluble phosphoric acid compounds such as potassium phosphate and sodium salt of orthophosphoric acid, allantoinchlorohydroxyaluminum,
Hinokitiol, ascorbic acid, lysozyme chloride, glycyrrhizic acid and salts thereof, sodium chloride, tranexamic acid, epsilon aminocaproic acid, dl-tocopherol acetate, azulene, glycyrrhetinic acid, sodium copper chlorophyllin, copper compounds of copper gluconate, aluminum lactate, strontium chloride , Potassium nitrate, berberine, hydroxamic acid and derivatives thereof, sodium tripolyphosphate, zeolite, dextranase, mutanase, amylase, methoxyethylene, maleic anhydride copolymer, polyvinylpyrrolidone, epidihydrocholesterine, dihydrocholesterol, zinc citrate, Extracts such as touki, oak, clove, rosemary, ogre, safflower, α-bisabonol, chlorhexidine salts, Rupirijiniumu, benzethonium chloride, trichlorocarbanilide and the like.

[0025]

According to the present invention, a refreshing feeling in the oral cavity can be obtained by the astringent action with a good aftertaste.

[0026]

EXAMPLES Hereinafter, the present invention will be described in detail with reference to experimental examples and examples, but the present invention is not limited to the following examples.

[Experimental Example] The raw materials shown in Table 1 were used, and the solvent was extracted with the extraction solvent shown in Table 1 at room temperature for one hour at regular intervals using an extraction solvent shown in Table 1 while stirring for a total of three times. The solvent was distilled off to obtain an extract. The feeling of use of this extract was evaluated by the following method. Table 1 shows the results. Evaluation method Using three healthy panels, the mouth was washed for 30 seconds using 20 ml of a test solution (aqueous solution containing 1% of solid content), and the intensity of astringency upon exhalation was scored according to the following criteria. The results were shown by the following evaluation from the total score. The aftertaste was evaluated for good or bad, and the number of people judged to be good was shown. Strength of astringency Efficacy rating Strong 3 Weak 2 Slight 1 No effect 0 Total of evaluation scores Efficacy rating 7-9 Strong ◎ 4-6 Weak ○ 1-3 Slight △ 0 No effect ×

[0028]

[Table 1]

Example 1 Toothpaste Calcium carbonate 50.00% Glycerin 20.00 Carrageenan 0.50 Carboxymethylcellulose 1.00 Lauryl diethanolamide 1.00 Sucrose monolaurate 2.00 Fragrance 1.00 Saccharin 0.0 10 Experiment No. 1 fruit juice dry matter 0.80 water remaining Total 100.00%

Example 2 Toothpaste Dicalcium phosphate dihydrate 50.00% Glycerin 20.00 Carboxymethylcellulose 2.00 Sodium lauryl sulfate 2.00 Fragrance 1.00 Saccharin sodium 0.10 2 extract 0.50 water remaining Total 100.00%

Example 3 Toothpaste Aluminum hydroxide 45.00% Gelling silica 2.00 Sorbit 25.00 Carboxymethylcellulose 1.00 Sodium lauryl sulfate 2.00 Fragrance 1.00 Saccharin sodium 0.10 1 dried fruit juice 0.50 6 extracts 0.05 water remaining Total 100.00%

Example 4 Toothpaste Precipitated silica 25.00% Glycerin 25.00 Sorbit 25.00 Lauroyl polyglycerin ester 1.00 Polyoxyethylene sorbitan monolaurate 2.00 Fragrance 1.00 Saccharin sodium 0.20 Experiment No. 3 extracts 0.30 water remaining Total 100.00%

[Example 5] Liquid dentifrice Aluminum hydroxide 25.00% Glycerin 40.00 Sorbit 15.00 Carboxymethylcellulose 0.20 Propylene glycol 2.00 Sodium lauryl sulfate 1.50 Decaglyceryl monolaurate 1.00 Fragrance 1 .00 Saccharin sodium 0.10 Experiment No. 4 extract 0.20 water remaining Total 100.00%

Example 6 Toothpaste Precipitated silica 20.00% Glycerin 25.00 Sorbit 35.00 Xanthan gum 0.20 Propylene glycol 2.00 Sodium lauryl sulfate 1.50 Decaglyceryl monolaurate 2.00 Fragrance 1. 00 Saccharin sodium 0.10 Experiment No. 5 extracts 0.30 water remaining Total 100.00%

Example 7 Oral Ointment Liquid Paraffin 15.00% Cetanol 10.00 Glycerin 20.00 Polyoxyethylene Sorbitan Fatty Acid Ester 5.00 Fragrance 0.50 Saccharin Sodium 0.10 4 extract 0.50 water remaining Total 100.00%

Example 8 Mouthwash Ethanol 20.00% Fragrance 1.00 Polyoxyethylene hydrogenated castor oil 0.30 Sodium monofluorophosphate 0.10 Sodium saccharin 0.05 2 extract 0.70 water remaining Total 100.00%

Example 9 Gargle Tablets Sodium Bicarbonate 54.50% Citric Acid 17.00 Anhydrous Sodium Sulfate 12.80 Dibasic Sodium Phosphate 10.00 Polyethylene Glycol 3.00 Sodium Monofluorophosphate 0.10 perfume 2.00 oleic acid 0.10 experiment No. 3 extracts 0.50 total 100.00%

Claims (1)

[Claims] An oral composition comprising a phyllans fruit or an extract thereof.