JPH09511218A - ヒトヘルペスウイルス7感染症の治療および予防についての2−アミノプリン誘導体の使用 - Google Patents
ヒトヘルペスウイルス7感染症の治療および予防についての2−アミノプリン誘導体の使用Info
- Publication number
- JPH09511218A JPH09511218A JP7513697A JP51369795A JPH09511218A JP H09511218 A JPH09511218 A JP H09511218A JP 7513697 A JP7513697 A JP 7513697A JP 51369795 A JP51369795 A JP 51369795A JP H09511218 A JPH09511218 A JP H09511218A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- treatment
- infection
- hhv
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1. ヒトを含む哺乳動物におけるHHV−7感染症の治療法(予防を含む) であって、かかる治療を必要とする哺乳動物に、有効量の式(A): の化合物または生物前駆体、あるいは前記した化合物のいずれかの医薬上許容さ れる塩、リン酸エステルおよび/またはアシル誘導体を投与することを特徴とす る方法。 2. HHV−7感染症の治療(予防を含む)にて用いるための医薬の製造に おける、式(A): の化合物または生物前駆体、あるいは前記した化合物のいずれかの医薬上許容さ れる塩、リン酸エステルおよび/またはアシル誘導体の使用。 3. 式(A): の化合物または生物前駆体、あるいは前記した化合物のいずれかの医薬上許容さ れる塩、リン酸エステルおよび/またはアシル誘導体と、医薬上許容される担体 とからなるHHV−7感染症の治療(予防を含む)用医薬組成物。 4. 治療がヒト免疫不全ウイルスに感染した患者におけるHHV−7感染症 に対するものである請求項1〜3のいずれか1つに記載の方法、使用または組成 物。 5. 化合物がファムシクロビルである請求項1〜4のいずれか1つに記載の 方法、使用または組成物。 6.ファムシクロビルを一日に2または3回、250mg、500mgまたは 750mgの用量で投与する請求項5記載の方法、使用または組成物。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939323404A GB9323404D0 (en) | 1993-11-12 | 1993-11-12 | Pharmaceuticals |
PCT/GB1994/002486 WO1995013074A1 (en) | 1993-11-12 | 1994-11-11 | Use of 2-amino purine derivatives for the treatment and prophylaxis of human herpes virus 7 infection |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH09511218A true JPH09511218A (ja) | 1997-11-11 |
JP3821840B2 JP3821840B2 (ja) | 2006-09-13 |
Family
ID=10745092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51369795A Expired - Fee Related JP3821840B2 (ja) | 1993-11-12 | 1994-11-11 | ヒトヘルペスウイルス7感染症の治療および予防についての2−アミノプリン誘導体の使用 |
Country Status (18)
Country | Link |
---|---|
US (1) | US6051579A (ja) |
EP (1) | EP0728002B1 (ja) |
JP (1) | JP3821840B2 (ja) |
KR (1) | KR100341736B1 (ja) |
CN (1) | CN1071572C (ja) |
AT (1) | ATE210445T1 (ja) |
AU (1) | AU696833B2 (ja) |
CA (1) | CA2176392C (ja) |
CY (1) | CY2337B1 (ja) |
DE (1) | DE69429447T2 (ja) |
DK (1) | DK0728002T3 (ja) |
ES (1) | ES2169117T3 (ja) |
GB (1) | GB9323404D0 (ja) |
HK (1) | HK1012234A1 (ja) |
PT (1) | PT728002E (ja) |
SI (1) | SI0728002T1 (ja) |
WO (1) | WO1995013074A1 (ja) |
ZA (1) | ZA948908B (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6475253B2 (en) | 1996-09-11 | 2002-11-05 | 3M Innovative Properties Company | Abrasive article and method of making |
US20040097528A1 (en) * | 2002-08-26 | 2004-05-20 | Ben-Zion Dolitzky | Crystalline solid famciclovir forms I, II, III and preparation thereof |
EP1932911A4 (en) * | 2005-09-08 | 2009-10-28 | Univ Osaka Res Found | PROMOTER FOR INTRODUCING A GENE IN LYMPHOCYTES OR BLOOD CELLS AND APPLYING THEREOF |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3485225D1 (de) * | 1983-08-18 | 1991-12-05 | Beecham Group Plc | Antivirale guanin-derivate. |
DE3582399D1 (de) * | 1984-09-20 | 1991-05-08 | Beecham Group Plc | Purin-derivate und ihre pharmazeutische verwendung. |
EP0216459B1 (en) * | 1985-07-27 | 1990-05-16 | Beecham Group Plc | 9-substituted guanine monohydrates |
GB8628826D0 (en) * | 1986-12-02 | 1987-01-07 | Beecham Group Plc | Pharmaceutical products |
US4795799A (en) * | 1987-09-08 | 1989-01-03 | Phillips Petroleum Company | Production of aromatic sulfide/ketone polymers with alkali metal carbonate |
CA2042931A1 (en) * | 1990-05-24 | 1991-11-25 | Robert Zahler | Fluorinated bis (hydroxymethyl) cyclobutyl purines and pyrimidines |
GB9015051D0 (en) * | 1990-07-07 | 1990-08-29 | Beecham Group Plc | Pharmaceutical treatment |
-
1993
- 1993-11-12 GB GB939323404A patent/GB9323404D0/en active Pending
-
1994
- 1994-11-10 ZA ZA948908A patent/ZA948908B/xx unknown
- 1994-11-11 AT AT95900830T patent/ATE210445T1/de active
- 1994-11-11 DK DK95900830T patent/DK0728002T3/da active
- 1994-11-11 SI SI9430409T patent/SI0728002T1/xx unknown
- 1994-11-11 DE DE69429447T patent/DE69429447T2/de not_active Expired - Lifetime
- 1994-11-11 JP JP51369795A patent/JP3821840B2/ja not_active Expired - Fee Related
- 1994-11-11 EP EP95900830A patent/EP0728002B1/en not_active Expired - Lifetime
- 1994-11-11 CN CN94194328A patent/CN1071572C/zh not_active Expired - Fee Related
- 1994-11-11 CA CA002176392A patent/CA2176392C/en not_active Expired - Fee Related
- 1994-11-11 AU AU81491/94A patent/AU696833B2/en not_active Ceased
- 1994-11-11 ES ES95900830T patent/ES2169117T3/es not_active Expired - Lifetime
- 1994-11-11 WO PCT/GB1994/002486 patent/WO1995013074A1/en active IP Right Grant
- 1994-11-11 PT PT95900830T patent/PT728002E/pt unknown
- 1994-11-11 KR KR1019960702484A patent/KR100341736B1/ko not_active IP Right Cessation
-
1998
- 1998-12-10 US US09/209,666 patent/US6051579A/en not_active Expired - Lifetime
- 1998-12-15 HK HK98113457A patent/HK1012234A1/xx not_active IP Right Cessation
-
2003
- 2003-03-11 CY CY0300023A patent/CY2337B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK0728002T3 (da) | 2002-04-08 |
US6051579A (en) | 2000-04-18 |
JP3821840B2 (ja) | 2006-09-13 |
DE69429447D1 (de) | 2002-01-24 |
DE69429447T2 (de) | 2002-07-25 |
KR100341736B1 (ko) | 2002-11-23 |
CY2337B1 (en) | 2004-02-06 |
AU696833B2 (en) | 1998-09-17 |
AU8149194A (en) | 1995-05-29 |
PT728002E (pt) | 2002-05-31 |
CN1136277A (zh) | 1996-11-20 |
EP0728002A1 (en) | 1996-08-28 |
SI0728002T1 (en) | 2002-04-30 |
CA2176392C (en) | 2005-11-08 |
CA2176392A1 (en) | 1995-05-18 |
HK1012234A1 (en) | 1999-07-30 |
ES2169117T3 (es) | 2002-07-01 |
ZA948908B (en) | 1995-08-17 |
ATE210445T1 (de) | 2001-12-15 |
EP0728002B1 (en) | 2001-12-12 |
CN1071572C (zh) | 2001-09-26 |
GB9323404D0 (en) | 1994-01-05 |
WO1995013074A1 (en) | 1995-05-18 |
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