CN1071572C - 使用2-氨基嘌呤衍生物治疗和预防人类疱疹病毒7感染 - Google Patents
使用2-氨基嘌呤衍生物治疗和预防人类疱疹病毒7感染 Download PDFInfo
- Publication number
- CN1071572C CN1071572C CN94194328A CN94194328A CN1071572C CN 1071572 C CN1071572 C CN 1071572C CN 94194328 A CN94194328 A CN 94194328A CN 94194328 A CN94194328 A CN 94194328A CN 1071572 C CN1071572 C CN 1071572C
- Authority
- CN
- China
- Prior art keywords
- treatment
- chemical compound
- formula
- hhv
- prophylaxis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Abstract
Description
HHV-7菌株SB | |||
化合物浓度μM | 感染%4天 | 感染%7天 | 抑制%7天 |
未感染者感染者PCV 51050100 | 0443 | 04942353436 | 21302931 |
Claims (4)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9323404.5 | 1993-11-12 | ||
GB939323404A GB9323404D0 (en) | 1993-11-12 | 1993-11-12 | Pharmaceuticals |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1136277A CN1136277A (zh) | 1996-11-20 |
CN1071572C true CN1071572C (zh) | 2001-09-26 |
Family
ID=10745092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN94194328A Expired - Fee Related CN1071572C (zh) | 1993-11-12 | 1994-11-11 | 使用2-氨基嘌呤衍生物治疗和预防人类疱疹病毒7感染 |
Country Status (18)
Country | Link |
---|---|
US (1) | US6051579A (zh) |
EP (1) | EP0728002B1 (zh) |
JP (1) | JP3821840B2 (zh) |
KR (1) | KR100341736B1 (zh) |
CN (1) | CN1071572C (zh) |
AT (1) | ATE210445T1 (zh) |
AU (1) | AU696833B2 (zh) |
CA (1) | CA2176392C (zh) |
CY (1) | CY2337B1 (zh) |
DE (1) | DE69429447T2 (zh) |
DK (1) | DK0728002T3 (zh) |
ES (1) | ES2169117T3 (zh) |
GB (1) | GB9323404D0 (zh) |
HK (1) | HK1012234A1 (zh) |
PT (1) | PT728002E (zh) |
SI (1) | SI0728002T1 (zh) |
WO (1) | WO1995013074A1 (zh) |
ZA (1) | ZA948908B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6475253B2 (en) | 1996-09-11 | 2002-11-05 | 3M Innovative Properties Company | Abrasive article and method of making |
US20040097528A1 (en) * | 2002-08-26 | 2004-05-20 | Ben-Zion Dolitzky | Crystalline solid famciclovir forms I, II, III and preparation thereof |
EP1932911A4 (en) * | 2005-09-08 | 2009-10-28 | Univ Osaka Res Found | PROMOTER FOR INTRODUCING A GENE IN LYMPHOCYTES OR BLOOD CELLS AND APPLYING THEREOF |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992000742A1 (en) * | 1990-07-07 | 1992-01-23 | Beecham Group Plc | Penciclovir and famciclovir and related guanine derivatives for the treatment of the hiv-1 infections |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3485225D1 (de) * | 1983-08-18 | 1991-12-05 | Beecham Group Plc | Antivirale guanin-derivate. |
DE3582399D1 (de) * | 1984-09-20 | 1991-05-08 | Beecham Group Plc | Purin-derivate und ihre pharmazeutische verwendung. |
EP0216459B1 (en) * | 1985-07-27 | 1990-05-16 | Beecham Group Plc | 9-substituted guanine monohydrates |
GB8628826D0 (en) * | 1986-12-02 | 1987-01-07 | Beecham Group Plc | Pharmaceutical products |
US4795799A (en) * | 1987-09-08 | 1989-01-03 | Phillips Petroleum Company | Production of aromatic sulfide/ketone polymers with alkali metal carbonate |
CA2042931A1 (en) * | 1990-05-24 | 1991-11-25 | Robert Zahler | Fluorinated bis (hydroxymethyl) cyclobutyl purines and pyrimidines |
-
1993
- 1993-11-12 GB GB939323404A patent/GB9323404D0/en active Pending
-
1994
- 1994-11-10 ZA ZA948908A patent/ZA948908B/xx unknown
- 1994-11-11 AT AT95900830T patent/ATE210445T1/de active
- 1994-11-11 DK DK95900830T patent/DK0728002T3/da active
- 1994-11-11 SI SI9430409T patent/SI0728002T1/xx unknown
- 1994-11-11 DE DE69429447T patent/DE69429447T2/de not_active Expired - Lifetime
- 1994-11-11 JP JP51369795A patent/JP3821840B2/ja not_active Expired - Fee Related
- 1994-11-11 EP EP95900830A patent/EP0728002B1/en not_active Expired - Lifetime
- 1994-11-11 CN CN94194328A patent/CN1071572C/zh not_active Expired - Fee Related
- 1994-11-11 CA CA002176392A patent/CA2176392C/en not_active Expired - Fee Related
- 1994-11-11 AU AU81491/94A patent/AU696833B2/en not_active Ceased
- 1994-11-11 ES ES95900830T patent/ES2169117T3/es not_active Expired - Lifetime
- 1994-11-11 WO PCT/GB1994/002486 patent/WO1995013074A1/en active IP Right Grant
- 1994-11-11 PT PT95900830T patent/PT728002E/pt unknown
- 1994-11-11 KR KR1019960702484A patent/KR100341736B1/ko not_active IP Right Cessation
-
1998
- 1998-12-10 US US09/209,666 patent/US6051579A/en not_active Expired - Lifetime
- 1998-12-15 HK HK98113457A patent/HK1012234A1/xx not_active IP Right Cessation
-
2003
- 2003-03-11 CY CY0300023A patent/CY2337B1/xx unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992000742A1 (en) * | 1990-07-07 | 1992-01-23 | Beecham Group Plc | Penciclovir and famciclovir and related guanine derivatives for the treatment of the hiv-1 infections |
Also Published As
Publication number | Publication date |
---|---|
DK0728002T3 (da) | 2002-04-08 |
US6051579A (en) | 2000-04-18 |
JP3821840B2 (ja) | 2006-09-13 |
DE69429447D1 (de) | 2002-01-24 |
DE69429447T2 (de) | 2002-07-25 |
KR100341736B1 (ko) | 2002-11-23 |
CY2337B1 (en) | 2004-02-06 |
AU696833B2 (en) | 1998-09-17 |
AU8149194A (en) | 1995-05-29 |
PT728002E (pt) | 2002-05-31 |
CN1136277A (zh) | 1996-11-20 |
EP0728002A1 (en) | 1996-08-28 |
SI0728002T1 (en) | 2002-04-30 |
CA2176392C (en) | 2005-11-08 |
CA2176392A1 (en) | 1995-05-18 |
HK1012234A1 (en) | 1999-07-30 |
ES2169117T3 (es) | 2002-07-01 |
ZA948908B (en) | 1995-08-17 |
ATE210445T1 (de) | 2001-12-15 |
JPH09511218A (ja) | 1997-11-11 |
EP0728002B1 (en) | 2001-12-12 |
GB9323404D0 (en) | 1994-01-05 |
WO1995013074A1 (en) | 1995-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: NOVARTIS INTERNATIONAL DRUG CO., LTD. Free format text: FORMER OWNER: SMITHKLINE BEECHAM PLC Effective date: 20011229 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20011229 Address after: Bermuda Hamilton Patentee after: Nova international medicines Ltd Address before: England Patentee before: Smithkline Beecham PLC |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20010926 Termination date: 20111111 |