JPH09510357A - 酸性繊維芽細胞成長因子（ａＦＧＦ）をコードする組み換えアデノウィルス - Google Patents

酸性繊維芽細胞成長因子（ａＦＧＦ）をコードする組み換えアデノウィルス

Info

Publication number
JPH09510357A
JPH09510357A JP7524416A JP52441695A JPH09510357A JP H09510357 A JPH09510357 A JP H09510357A JP 7524416 A JP7524416 A JP 7524416A JP 52441695 A JP52441695 A JP 52441695A JP H09510357 A JPH09510357 A JP H09510357A
Authority
JP
Japan
Prior art keywords
adenovirus
afgf
sequence
cells
recombinant adenovirus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7524416A
Other languages
English (en)
Japanese (ja)
Inventor
パスカル バルヌー，
ピヤ デラエール，
ミシエル ペリコーデ，
ローラン プラデイエ，
エマニユエル ビニユ，
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH09510357A publication Critical patent/JPH09510357A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factors [FGF]
    • C07K14/501—Fibroblast growth factors [FGF] acidic FGF [aFGF]
JP7524416A 1994-03-18 1995-03-02 酸性繊維芽細胞成長因子（ａＦＧＦ）をコードする組み換えアデノウィルス Pending JPH09510357A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9403190A FR2717495B1 (fr) 1994-03-18 1994-03-18 Virus recombinants, préparation et utilisation en thérapie génique.
FR94/03190 1994-03-18
PCT/FR1995/000249 WO1995025803A1 (fr) 1994-03-18 1995-03-02 ADENOVIRUS RECOMBINANTS CODANT POUR LE FACTEUR DE CROISSANCE DES FIBROBLASTES ACIDES (aFGF)

Publications (1)

Publication Number Publication Date
JPH09510357A true JPH09510357A (ja) 1997-10-21

Family

ID=9461189

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7524416A Pending JPH09510357A (ja) 1994-03-18 1995-03-02 酸性繊維芽細胞成長因子（ａＦＧＦ）をコードする組み換えアデノウィルス

Country Status (8)

Country Link
EP (1) EP0750675A1 (fr)
JP (1) JPH09510357A (fr)
AU (1) AU1896195A (fr)
CA (1) CA2184409A1 (fr)
FR (1) FR2717495B1 (fr)
IL (1) IL112993A (fr)
WO (1) WO1995025803A1 (fr)
ZA (1) ZA952242B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007161704A (ja) * 2005-12-09 2007-06-28 Koshi Tei 神経損傷を処置するためのまたは神経細胞を再生するための組成物
WO2009128474A1 (fr) 2008-04-16 2009-10-22 財団法人化学及血清療法研究所 Procédé de production d'une préparation de feuille bioabsorbable sur laquelle de la thrombine a été immobilisée

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2188575A1 (fr) * 1995-02-28 1996-09-06 H. Kirk Hammond Therapie angiogenique par transfert de genes
US5792453A (en) * 1995-02-28 1998-08-11 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
CA2370404A1 (fr) * 1999-04-26 2000-11-02 Serge Adnot Utilisation d'adenovirus recombinant defectif comprenant un acide nucleique codant pour un facteur angiogenique pour le traitement de l'hypertension arterielle pulmonaire
FR2792531B1 (fr) * 1999-04-26 2003-01-31 Aventis Pharma Sa Utilisation d'adenovirus recombinant defectif comprenant un acide nucleique codant pour un facteur angiogenique pour le traitement de l'hypertension arterielle pulmonaire
KR100812884B1 (ko) * 2000-11-27 2008-03-11 가부시키가이샤 디나벡크 겐큐쇼 혈관신생 유전자를 코드하는 파라믹소바이러스 벡터 및 그 이용

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2814529B2 (ja) * 1989-03-16 1998-10-22 味の素株式会社 虚血性脳障害治療薬
JPH06503962A (ja) * 1990-12-18 1994-05-12 アムジエン・インコーポレーテツド 増強された安定性及び生物学的活性を有する酸性線維芽細胞成長因子の類似体
US5733871A (en) * 1991-11-08 1998-03-31 The General Hospital Corporation Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration
FR2688514A1 (fr) * 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
DE69334238D1 (de) * 1992-09-25 2008-09-25 Aventis Pharma Sa Adenovirus vektoren für die übertragung fremder gene in zellen des zentralen nervensystems, insbesondere im gehirn
FR2704234B1 (fr) * 1993-04-22 1995-07-21 Centre Nat Rech Scient Virus recombinants, preparation et utilisation en therapie genique.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007161704A (ja) * 2005-12-09 2007-06-28 Koshi Tei 神経損傷を処置するためのまたは神経細胞を再生するための組成物
WO2009128474A1 (fr) 2008-04-16 2009-10-22 財団法人化学及血清療法研究所 Procédé de production d'une préparation de feuille bioabsorbable sur laquelle de la thrombine a été immobilisée

Also Published As

Publication number Publication date
EP0750675A1 (fr) 1997-01-02
IL112993A0 (en) 1995-06-29
IL112993A (en) 2006-09-05
AU1896195A (en) 1995-10-09
WO1995025803A1 (fr) 1995-09-28
CA2184409A1 (fr) 1995-09-28
FR2717495A1 (fr) 1995-09-22
FR2717495B1 (fr) 1996-04-12
ZA952242B (en) 1996-01-09

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