IL112993A - Recombinant viruses, their preparation and their use in gene therapy - Google Patents

Recombinant viruses, their preparation and their use in gene therapy

Info

Publication number
IL112993A
IL112993A IL112993A IL11299395A IL112993A IL 112993 A IL112993 A IL 112993A IL 112993 A IL112993 A IL 112993A IL 11299395 A IL11299395 A IL 11299395A IL 112993 A IL112993 A IL 112993A
Authority
IL
Israel
Prior art keywords
afgf
implant according
sequence
adenovirus
cell
Prior art date
Application number
IL112993A
Other languages
English (en)
Other versions
IL112993A0 (en
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of IL112993A0 publication Critical patent/IL112993A0/xx
Publication of IL112993A publication Critical patent/IL112993A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factors [FGF]
    • C07K14/501—Fibroblast growth factors [FGF] acidic FGF [aFGF]
IL112993A 1994-03-18 1995-03-14 Recombinant viruses, their preparation and their use in gene therapy IL112993A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403190A FR2717495B1 (fr) 1994-03-18 1994-03-18 Virus recombinants, préparation et utilisation en thérapie génique.

Publications (2)

Publication Number Publication Date
IL112993A0 IL112993A0 (en) 1995-06-29
IL112993A true IL112993A (en) 2006-09-05

Family

ID=9461189

Family Applications (1)

Application Number Title Priority Date Filing Date
IL112993A IL112993A (en) 1994-03-18 1995-03-14 Recombinant viruses, their preparation and their use in gene therapy

Country Status (8)

Country Link
EP (1) EP0750675A1 (fr)
JP (1) JPH09510357A (fr)
AU (1) AU1896195A (fr)
CA (1) CA2184409A1 (fr)
FR (1) FR2717495B1 (fr)
IL (1) IL112993A (fr)
WO (1) WO1995025803A1 (fr)
ZA (1) ZA952242B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2188575A1 (fr) 1995-02-28 1996-09-06 H. Kirk Hammond Therapie angiogenique par transfert de genes
US5792453A (en) * 1995-02-28 1998-08-11 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
FR2792531B1 (fr) * 1999-04-26 2003-01-31 Aventis Pharma Sa Utilisation d'adenovirus recombinant defectif comprenant un acide nucleique codant pour un facteur angiogenique pour le traitement de l'hypertension arterielle pulmonaire
KR20020001846A (ko) * 1999-04-26 2002-01-09 추후제출 폐순환승압을 치료하기 위한 맥관형성 인자를 암호화 하는핵산을 포함하는 재조합 결손 아데노바이러스의 용도
CA2430112C (fr) 2000-11-27 2010-07-27 Dnavec Research Inc. Vecteur de paramyxovirus encodant le gene de l'angiogenese et son utilisation
US20070134204A1 (en) * 2005-12-09 2007-06-14 Henrich Cheng Method for treating nerve injury and vector construct for the same
WO2009128474A1 (fr) 2008-04-16 2009-10-22 財団法人化学及血清療法研究所 Procédé de production d'une préparation de feuille bioabsorbable sur laquelle de la thrombine a été immobilisée

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2814529B2 (ja) * 1989-03-16 1998-10-22 味の素株式会社 虚血性脳障害治療薬
NZ241021A (en) * 1990-12-18 1993-12-23 Amgen Inc Analogues of acidic fibroblast growth factor and pharmaceutical
AU3129793A (en) * 1991-11-08 1993-06-07 General Hospital Corporation, The Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration
FR2688514A1 (fr) * 1992-03-16 1993-09-17 Centre Nat Rech Scient Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant.
CA2145535C (fr) * 1992-09-25 2007-07-17 Axel Kahn Vecteurs adenoviraux pour le transfert de genes etrangers dans des cellules du systeme nerveux central, notamment dans le cerveau
FR2704234B1 (fr) * 1993-04-22 1995-07-21 Centre Nat Rech Scient Virus recombinants, preparation et utilisation en therapie genique.

Also Published As

Publication number Publication date
ZA952242B (en) 1996-01-09
EP0750675A1 (fr) 1997-01-02
FR2717495A1 (fr) 1995-09-22
WO1995025803A1 (fr) 1995-09-28
CA2184409A1 (fr) 1995-09-28
AU1896195A (en) 1995-10-09
FR2717495B1 (fr) 1996-04-12
JPH09510357A (ja) 1997-10-21
IL112993A0 (en) 1995-06-29

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees