JPH092931A - Cosmetic - Google Patents

Abstract

PURPOSE: To obtain a cosmetic, having ultralow skin irritancy and excellent in preservation stability and organoleptic characteristics in use. CONSTITUTION: This cosmetic contains 0.01-5wt.% di-hydrophobic group and di-hydrophilic group type anionic surfactant of formula I or II (the number of carbon atoms in acyl groups is 20, 18, 16, 14, 12, 10 or 8; M1 and M2 are each H, a mono- or a bivalent alkali metallic ion, ammonium ion or an organic ammonium ion; X1 and X2 are each a 1-12C hydrocarbon chain; R3 is a residue of an amino acid molecule) and is prepared into a foundation cosmetic, a makeup cosmetic, a cosmetic for hair of the head, etc., by, as necessary, suitably blending other surfactants, emulsifying assistants, perfumes, colorants, preservatives, pigments, etc. Thereby, a skin cosmetic having sufficient skin safety so as to satisfy consumers suffering from hypersensitive skin is obtained.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic having extremely low skin irritation, excellent storage stability and excellent organoleptic properties.

[0002]

2. Description of the Related Art Conventionally, (a) salts of sulfuric acid esters of aliphatic higher alcohols, phosphoric acid esters of aliphatic higher alcohols, N-long chain acylglutamic acid, etc. and basic substances such as caustic soda, caustic potash, triethanolamine, etc. Anionic surfactants, (b) ether type nonionic surfactants such as ethylene oxide adducts of aliphatic higher alcohols, (c) ester type nonionic surfactants composed of higher fatty acids and polyhydric alcohols, etc. Skin cosmetics containing as an emulsifier main component are known. However, these skin cosmetics cannot be said to have sufficient skin safety for consumers with sensitive skin disorders, and improvement thereof has been desired.

[0003]

The problem to be solved by the present invention is to develop a skin cosmetic which has sufficient skin safety so that consumers with sensitive dermatosis can also be satisfied.

[0004]

The present inventors have conducted intensive studies in view of the above circumstances, and as a result, the following emulsified skin cosmetics have excellent skin safety and surprisingly excellent storage stability. , Also have excellent sensory characteristics,
The present invention has been completed.

That is, the present invention provides the following (A) or (B)
And a hydrophobic group 2 hydrophilic group type anionic surfactant represented by

[0006]

Embedded image

(The carbon number of the acyl group is 20, 18, 16,
14, 12, 10 or 8, M ₁ is hydrogen, a monovalent or divalent alkali metal ion, an ammonium ion or an organic ammonium ion, and X ₁ is a carbon number of 1 to 1.
12 saturated or unsaturated hydrocarbon chains. )

[0008]

Embedded image

(The carbon number of the acyl group is 20, 18, 16,
14, 12, 10 or 8, R ₃ is a residue of an amino acid molecule, M ₂ is hydrogen, a monovalent or divalent alkali metal ion, ammonium ion or organic ammonium ion, and X ₂ is carbon. It is a saturated or unsaturated hydrocarbon chain of the number 1 to 12. )

Examples of the residue of the amino acid molecule of R ₃ include, but are not limited to, amino acid residues such as glutamic acid, aspartic acid, glycine, alanine, valine, arginine, histidine and lysine. .

Next, the structure of the present invention will be described. Of the present invention,
The 2 hydrophobic group 2 hydrophilic group type anionic surfactant represented by (A) can be produced, for example, according to the reaction formula shown in Table 1 below. That is, it is a method in which alkylenediamine is diacylated, the obtained product is reacted with sodium 2-halogenated ethanesulfonate to introduce a sulfone group, and then neutralized with an appropriate base.

The counter ion (M ₁ ) used here is a monovalent or divalent alkali metal such as sodium or potassium, an ammonium ion, an organic base such as triethanolamine, isopropanolamine or lysine, or an ammonium such as a basic amino acid. Ions are applied.

2 hydrophobic groups 2 of the present invention obtained by the above method
The hydrophilic group-containing anionic surfactant may be obtained as a mixture in some cases, but the desired surfactant can be isolated by an appropriate purification means.

[0014]

[Table 1]

The 2 hydrophobic group 2 hydrophilic group type anionic surfactant represented by (A) can also be produced by the method shown in the following Table 2 using, for example, taurine.

[0016]

[Table 2]

Here, the carbon number of the acyl group is 20, 1
8, 16, 14, 12, 10, or 8, and the counter ion (M ₁ ) is arbitrarily selected from monovalent or divalent alkali metal ions, ammonium ions, and organic ammonium ions. X ₁ is a 1 to 12 saturated or unsaturated hydrocarbon chain.

The 2 hydrophobic group 2 hydrophilic group type anionic surfactant represented by (B) of the present invention is the same as in the above-mentioned method of Table 2, except that glutamic acid, aspartic acid, glycine, alanine and valine are used instead of taurine. , Amino acids such as monoaminocarboxylic acids such as arginine, histidine, and lysine, monoaminodicarboxylic acids, diaminomonocarboxylic acids, and the like.

2 represented by (A) or (B) of the present invention
The content of the hydrophobic group 2 hydrophilic group type anionic surfactant is preferably 0.01 to 5% by weight based on the total amount of the cosmetic (composition).

Further, as shown in the experimental examples described later, the 2-hydrophobic group 2-hydrophilic group type anionic surfactant of the present invention is superior in skin safety as compared with the conventional anionic surfactant.

A skin safety test was conducted in accordance with the "human skin patch test" described below, using an aqueous solution containing 0.001 mol of the 2 hydrophobic group 2 hydrophilic group type anionic surfactant of the present invention in 100 g. The results obtained are shown in Tables 3 and 4.

[0022]

[Table 3]

[0023]

[Table 4]

The cosmetic of the present invention comprises 2 hydrophobic groups 2 as described above.
It is composed of a hydrophilic group type anionic surfactant, but if necessary, other surfactants, emulsification aids, perfumes, colorants, preservatives, pigments, etc. within the range to achieve the object of the present invention. It is also possible to properly mix them.

The cosmetics of the present invention include skin milk,
Examples include basic cosmetics such as skin creams, foundation creams, massage creams, facial cleansing creams, lotions, scalp treatments, hair creams, hair shampoos, hair conditioners, makeup cosmetics, and hair cosmetics.

[0026]

The present invention will be described below with reference to examples. Test methods or measurement methods for the storage stability test, human skin patch test, and feel (sensory test during use) described in the examples are shown below.

(1) Storage stability test The sample was placed in a constant temperature bath at 45 ° C., and the emulsified state and appearance after standing for 6 months were observed. If no abnormality was observed (emulsion state was uniform and homogeneous emulsion When formed), it was evaluated as good, and when abnormalities were observed (when oil was separated, when particles became coarse, etc.), it was evaluated as poor.

(2) Human Skin Patch Test On the skin of the forearm flexor side of 25 subjects, 0.1 g of the sample was occluded for 24 hours using a patch test plaster with a circular lint cloth having a diameter of 1.0 cm. After the cloth was applied, the skin condition of 25 test subjects was evaluated for each sample according to the criteria shown in Table 5 below. The result of the determination was the one with the strongest reaction after 1 hour and 24 hours after the bandage removal, and was indicated by the number of people with an evaluation of (±) or more.

[0029]

[Table 5]

(3) Feeling (sensory test during use) Twenty female test subjects were applied twice a day in the morning and evening for 30 days to carry out a sensory test to test the moisturizing and irritating properties. Evaluation is "moist after use" for moisture retention
The number of respondents who answered "I feel irritation after use" was indicated by the number of respondents who answered "I feel irritation after use."

Examples 1 to 7 and Comparative Examples 1 to 4 [Skin milk] Examples and comparative examples were prepared by mixing various emulsifier components as shown in Table 6 and various raw materials as shown in Table 7. An example skin milk was prepared and tested for various properties.

[0032]

[Table 6]

(1) Composition

[Table 7]

(2) Preparation method The components (a) and (b) are uniformly dissolved at a temperature of 80 ° C., and the component (b) is injected while stirring the component (a) and emulsified and dispersed. Prepare by cooling to a temperature of 30 ° C. with stirring. (3) Characteristics Table 6 shows the results of testing the various characteristics according to each example and comparative example. From these results, it is clear that the skin milk of the present invention is excellent in skin safety, storage stability and organoleptic properties during use.

Example 8 [Scalp Treatment (Scalp Treatment)] (1) Composition (1) R ₁ CO group has 18 carbon atoms (stearoyl group), X is an ethylene group, and M is ₁ is triethanol ammonium ion (A) anionic surfactant (2) 1,3-butylene glycol 6.5 (3) polyethylene glycol 1500 5.0 (4) ethanol 5.5 (5) causticari 0 .05 (6) Purified water 46.95 (7) 2-Hexyldecyl palmitate 10.0 (8) Squalane 5.0 (9) Butylparaben 0.2 (10) Vitamin C 0.15 (11) Perfume 0 .05 (12) Purified water 19.9 (13) Carboxyvinyl polymer 0.2 These numerical values are wt% with respect to the total amount of the composition, and are the same in the following examples.

(2) Preparation method A solution of (7), (8), (9), (10) and (11) dissolved at 75 ° C. was maintained at 75 ° C. (1), (2), ( 3), (4) and (6) were added with stirring and cooled with stirring to obtain a scalp treatment.

(3) Characteristics The scalp treatment of the present invention was excellent in skin safety, storage stability and sensory characteristics during use.

Example 9 [Cream foundation] (1) Composition (1) Cetostearyl alcohol 1.0 (2) Jojoba oil 15.0 (3) Glycerin monostearate 2.0 (4) Propylene glycol monolaurate 3. 0 (5) R ₁ CO group having 18 carbon atoms (stearoyl group), X ₁ is 0.5 propylene group, and M ₁ is ammonium ion (A) anionic surfactant (6) Propylene glycol 4.0 (7) Methylparaben 0.3 (8) Perfume 0.1 (9) Purified water Residue of all components (10) Titanium oxide 8.0 (11) Talc 4.0 (12) Iron oxide 0.0. 5

(2) Preparation method Oil phase components (1), (2), (3), (4) and aqueous phase components (5), (6)
, (7), (8) and (9) and the pigment components (10), (11) and (12) were mixed by a conventional method to obtain a cream foundation.

(3) Characteristics The obtained cream foundation was excellent in skin safety, storage stability and sensory characteristics during use.

Example 10 [Cream foundation] (5) was prepared by using R ₂ CO having 18 carbon atoms, M ₂ being an ammonium ion, X ₂ being an ethylene group, and R ₃ being a glutamic acid residue. A cream foundation was obtained in the same manner as in Example 9 except that the anionic surfactant of 2 hydrophobic groups and 2 hydrophilic groups shown in (B) was used.

The obtained cream foundation was excellent in skin safety, storage stability and sensory characteristics during use.

Example 11 [Lotion] (1) Composition (1) R ₁ CO has 8 carbon atoms, X ₁ is a propylene group, and 0.5 hydrophilic group is unneutralized (A). Anionic surfactant of (2) Glycerin 4.0 (3) 1,3 Butylene glycol 4.0 (4) Ethanol 7.0 (5) Methylparaben 0.5 (6) Citric acid 0.01 (7) Citric acid Acid soda 0.1 (8) Perfume 0.05 (9) Purified water 84.24

(2) Preparation Method The above components were mixed by a conventional method to obtain a lotion. (3) Characteristics The obtained lotion was excellent in skin safety, storage stability and sensory characteristics during use.

Example 12 [Lotion] (1) The two hydrophobic groups represented by (A) in which R ₁ CO has 12 carbon atoms, M ₁ is Na ion, and X ₁ is ethylene group. 2 hydrophilic group type anionic surfactant 0.2 and R
₂ CO ₂ has 18 carbon atoms, M ₂ is an ammonium ion, X ₂ is an ethylene group, and R ₃ is a glutamic acid residue. 2 Hydrophobic group 2 Hydrophilic group type anionic interface represented by (B) A lotion was obtained in the same manner as in Example 11 except that the active agent was changed to 0.5.

The lotion thus obtained was excellent in skin safety, storage stability and sensory characteristics during use.

[0047]

As described above, the cosmetic of the present invention is excellent in skin safety, storage stability and organoleptic properties during use, and is extremely useful.

Claims (1)

[Claims] 1. A cosmetic comprising two hydrophobic groups and two hydrophilic groups type anionic surfactants represented by the following (A) or (B). Embedded image (The carbon number of the acyl group is 20, 18, 16, 14, 12,
10 or 8, M ₁ is hydrogen, monovalent or divalent alkali metal ion, ammonium ion or organic ammonium ion, and X ₁ is a saturated or unsaturated hydrocarbon chain having 1 to 12 carbon atoms. ) (The carbon number of the acyl group is 20, 18, 16, 14, 12,
10 or 8, R ₃ is a residue of an amino acid molecule, M ₂ is hydrogen, a monovalent or divalent alkali metal ion, an ammonium ion or an organic ammonium ion, and X ₂ is a carbon number of 1 to 12 Of saturated or unsaturated hydrocarbon chains. )