JP3426400B2 - Cosmetics - Google Patents

Description

Description: BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic having extremely low skin irritation, excellent storage stability and excellent organoleptic properties. 2. Description of the Related Art Conventionally, (a) sulfuric acid esters of aliphatic higher alcohols, phosphoric acid esters of aliphatic higher alcohols, N-long chain acylglutamic acid and the like and basic substances such as caustic soda, caustic potash and triethanolamine Anionic surfactants which are salts of (ii) ether-type nonionic surfactants such as ethylene oxide adducts of aliphatic higher alcohols, and (iii) ester-type nonionic surfactants comprising higher fatty acids and polyhydric alcohols Skin cosmetics containing an activator or the like as a main emulsifier are known. However, these skin cosmetics cannot be said to have sufficient skin safety for consumers with sensitive dermatosis, and improvement thereof has been desired. [0003] The problem to be solved by the present invention is to develop a skin cosmetic which has sufficient skin safety to satisfy consumers with sensitive dermatosis. [0004] The present inventors have conducted intensive studies in view of the above-mentioned circumstances, and as a result, the following emulsified skin cosmetics have excellent skin safety and have unexpectedly storage stability. It is found that it has excellent properties and also has excellent sensory characteristics,
The present invention has been completed. That is, the present invention provides a compound represented by the general formula (1): (However, the carbon number of RCO in the formula is 20, 18, 16, 1
4, 12, 10 and 8, wherein X is hydrogen or an alkali metal ion, ammonium ion or organic ammonium ion). It is a cosmetic characterized by being contained in an amount of from 0.01 to 10% by weight. Next, the configuration of the present invention will be described. The two amide group-containing two hydrophobic group-two hydrophilic group-containing anionic surfactants of the present invention can be produced, for example, according to the reaction formula shown in Table 1 below. That is, this is a method in which methylenebis (sodium 2-aminoethanesulfonate) obtained by reacting sodium 2-aminoethanesulfonate with formaldehyde is acylated and, if necessary, neutralized with an appropriate base. As a counter ion used here, an alkali metal such as sodium or potassium, an ammonium ion, an organic base such as triethanolamine, isopropanolamine, or lysine, or an ammonium ion such as a basic amino acid are applied. The amide group-containing 2 of the present invention obtained by the above method
The anionic surfactant containing a hydrophobic group 2 and a hydrophilic group may be obtained as a mixture, but the desired surfactant can be isolated by an appropriate purification means. [Table 1] The compounding amount of the amide group-containing two hydrophobic group-two hydrophilic group-containing anionic surfactant of the present invention is determined by the amount of the cosmetic (composition)
0.01 to 10% by weight based on the total amount of
%), Preferably 0.05 to 5% by weight. If it is less than 0.01 wt%, it is difficult to obtain a skin cosmetic which achieves the object of the present invention, and if it exceeds 10 wt%, it is not preferable in terms of feeling of use. Further, as shown in the experimental examples described below, the anionic surfactants containing two amide groups and two hydrophobic groups and two hydrophilic groups are more excellent in skin safety than conventional anionic surfactants. I have. It is also excellent in stability in aqueous systems, especially under acidic conditions. An aqueous solution containing 0.001 mol of an amide group-containing two hydrophobic group-two hydrophilic group-containing anionic surfactant in 100 g of the present invention was used as a sample, and skin safety was measured according to the "human skin patch test" described below. A sex test was performed. Table 2 shows the results. [Table 2] The cosmetic of the present invention has two hydrophobic groups 2 as described above.
It consists of a hydrophilic group-containing anionic surfactant,
If necessary, other surfactants, emulsifying auxiliaries, fragrances, coloring agents, preservatives, pigments and the like can be appropriately compounded within a range that achieves the object of the present invention. Skin cosmetics of the present invention include skin milk, skin cream, foundation cream, massage cream, face wash cream, lotion,
It is applied to basic cosmetics such as scalp treatment, hair cream, hair shampoo and hair rinse, makeup cosmetics, and hair cosmetics. Hereinafter, the present invention will be described with reference to examples. Test methods or measurement methods for the storage stability test, human skin patch test, and feel (sensory test during use) described in the examples are shown below. (1) Storage stability test A sample was placed in a thermostat at 45 ° C., and after standing for 6 months, the emulsified state and appearance were observed. If no abnormality was observed (a homogeneous emulsion having a uniform emulsified state was observed). (If formed) was regarded as good, and if abnormalities were observed (such as when oil separated or particles became coarse), it was regarded as poor. (2) Human skin patch test A 0.1 g sample was applied to the skin of the flexed side of the forearm of 25 subjects using a patch test bandage with a circular lint cloth having a diameter of 1.0 cm for 24 hours. After spreading, the skin condition of 25 subjects was evaluated and determined for each sample according to the criteria shown in Table 3 below. The result of the determination was the one with the strongest reaction after 1 hour and 24 hours after the bandage removal, and was indicated by the number of people with an evaluation of (±) or more. [Table 3] (3) Feeling (Sensory test at the time of use) A sensory test was carried out by applying 20 times in the morning and evening for 30 days by 20 testee girls, and a moisturizing property and an irritation property were tested. Evaluation is "moist after use" for moisture retention
The number of respondents and the irritancy are indicated by the number of respondents who "feel the stimulus after use." Examples 1 to 4, Comparative Examples 1 to 4 [Skin milk] Various emulsifier components were blended as shown in Table 4, and various raw materials were blended as shown in Table 5. Example skin milks were prepared and tested for properties. [Table 4] (1) Composition (2) Preparation method The components (A) and (B) are each uniformly dissolved at a temperature of 80 ° C., and the component (B) is injected while the component (A) is stirred and emulsified and dispersed. Prepare by cooling to a temperature of 30 ° C. with stirring. (3) Characteristics Table 4 shows the results of testing the various characteristics according to the examples and comparative examples. From these results, it is clear that the skin milk of the present invention is excellent in skin safety, storage stability and organoleptic properties during use. Example 5 [Scalp Cosmetic (Scalp Treatment)] (1) Composition (1) The acyl group of general formula (1) has 18 (stearoyl group) carbon atoms of 4.5 and a counter ion of tris. Anionic surfactant of the present invention which is an ethanol ammonium ion (2) 1,3-butylene glycol 4.5 (3) Polyethylene glycol 1500 3.0 (4) Ethanol 5.5 (5) Kaseikari 0.05 (6) Purified water 46.95 (7) 2-hexyldecyl palmitate 10.0 (8) Squalane 5.0 (9) Butylparaben 0.2 (10) Vitamin C 0.15 (11) Fragrance 0.05 (12 ) Purified water 19.9 (13) Carboxyvinyl polymer 0.2 These values are wt% based on the total amount of the composition, and the same applies to the following examples. (2) Preparation method (7), (8), (9), (10) and (11) dissolved at 75 ° C. were maintained at 75 ° C. (1), (2) , (3), (4) and (6)
The mixture was added with stirring and cooled while stirring to obtain a scalp treatment. (3) Characteristics The scalp treatment of the present invention was excellent in skin safety, storage stability and sensory characteristics during use. Example 6 [Cream Foundation] (1) Composition (1) Cetostearyl alcohol 1.0 (2) Jojoba oil 15.0 (3) Glycerin monostearate 2.0 (4) Propylene glycol monolaurate 0 (5) The anionic surfactant of the present invention wherein the acyl group of the general formula (1) has 18 (stearoyl group) carbon atoms of 0.5 and the counter ion is an ammonium ion. (6) Propylene glycol 4 0.0 (7) Methylparaben 0.3 (8) Fragrance 0.1 (9) Purified water Residue of all components (10) Titanium oxide 8.0 (11) Talc 4.0 (12) Iron oxide 0.5 (2) Preparation method Oil phase components (1), (2), (3), (4) and aqueous phase components (5), (6)
, (7), (8) and (9) and the pigment components (10), (11) and (12) were mixed by a conventional method to obtain a cream foundation. (3) Characteristics The cream foundation of the present invention was excellent in skin safety, storage stability and sensory characteristics during use. Example 7 [Lotion] (1) Composition (1) Anionic interface of the present invention in which the acyl group of the general formula (1) has 8 carbon atoms and the hydrophilic group is a medium 0.5 sum. Activator (2) Glycerin 4.0 (3) 1,3-butylene glycol 4.0 (4) Ethanol 7.0 (5) Methylparaben 0.5 (6) Citric acid 0.01 (7) Sodium citrate 0. 1 (8) Fragrance 0.05 (9) Purified water 84.24 (2) Preparation method The above components were mixed by a conventional method to obtain a lotion. (3) Characteristics The lotion of the present invention was excellent in skin safety, storage stability and sensory characteristics during use. As described above, the cosmetic of the present invention has excellent skin safety, storage stability and organoleptic properties during use, and is extremely useful.

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Claims (1)

(57) [Claims] [Claim 1] General formula (1) (However, the carbon number of RCO in the formula is 20, 18, 16, 1
4, 12, 10, 8 wherein X is hydrogen or an alkali metal ion, an ammonium ion, or an organic ammonium ion). Cosmetics characterized by being added in an amount of from 0.01 to 5% by weight.