JPH1171262A - Cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic, capable of retaining 2,000 mPa.s or more of viscosity in spite of a metallic compound contained therein, excellent in stability and good in sense of use. SOLUTION: This cosmetic contains (A) a metallic compound selected from metallic oxides, inorganic metallic salts and organometallic salts and (B) a water-soluble polysaccharide derivative in which a part or all of hydrogen atoms of hydroxy group in polysaccharides or derivatives thereof are substituted by (a) a substituent group having a hydrophobic moiety selected from 8-40C straight-chain or branched chain alkyl groups, alkenyl groups, arylalkyl groups and alkylaryl groups and (b) a substituent group having a nonionic or an ionic hydrophilic moiety which may be substituted by hydroxyl group in (1/1,000) to (100/1) ratio of the substitutent groups (a) to (b). The cosmetic has >=2,000 mPa.s viscosity at 25 deg.C.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic which contains a metal compound, maintains a viscosity of 2000 mPa.s or more, has excellent stability, has no sticky feeling, has good spreadability, and has a good feeling in use.

[0002]

2. Description of the Related Art Conventionally, various metal compounds have been added to cosmetics for the purpose of improving the ultraviolet protection effect, the emulsion stability, the preservability, the astringent effect, the feel and the like. However, in general, when a metal compound is blended, a decrease in viscosity, separation of emulsification, precipitation and sedimentation of the metal compound, and the like occur.
In a liquid cosmetic having a viscosity of 0 mPa · s or more, it was not possible to maintain a desired viscosity and obtain a stable cosmetic. Also, even if the stability is improved by increasing the thickening agent such as a polymer compound or reducing the compounding amount of the metal compound, stickiness occurs, the spread deteriorates, and the feeling of use is deteriorated. The effect of the metal compound could not be sufficiently obtained.

[0003]

SUMMARY OF THE INVENTION An object of the present invention is to maintain a viscosity of 2,000 mPa · s or more while containing a metal compound, and to have excellent stability, good feeling in use, and sufficient effects of the metal compound. It is to provide a cosmetic that can be obtained.

[0004]

The present invention comprises the following components (A) and (B) and has a viscosity at 25 ° C. of 20:
The purpose of the present invention is to provide a cosmetic that is at least 00 mPa · s. (A) a metal compound selected from metal oxides, inorganic metal salts and organic metal salts, (B) a part or all of the hydrogen atoms of the hydroxyl group of the polysaccharide or a derivative thereof is (a) a compound having 8 to 40 carbon atoms. A linear or branched alkyl group, an alkenyl group, an arylalkyl group and a substituent having a hydrophobic part selected from an alkylaryl group, and (b) an ionic or nonionic hydrophilic group which may be substituted by a hydroxyl group A water-soluble polysaccharide derivative which is substituted with a substituent having a moiety and has a ratio of the substituent (a) to the substituent (b) of 1: 1000 to 100: 1.

[0005]

BEST MODE FOR CARRYING OUT THE INVENTION Among the components (A), examples of the metal oxide include various titanium oxides (for example, JP-A-57-67681) and various zinc oxides (for example, JP-A-62) which are used as ultraviolet protection agents. 228006, JP-A-1-1-1
No. 75921), various iron oxides, cerium oxides, zirconium oxides and the like, or composite powders of these with other organic powders and inorganic powders. Further, these may be surface-treated with silica, silicone, alumina, metal soap, fatty acid, amino acid, alkyl phosphoric acid, fluorine compound, N-acyl glutamic acid, perfluoroalkyl phosphate, or the like. These shapes, sizes,
The form is not particularly limited, and it may be used in the form of a sol or the like.

Examples of the inorganic metal salts include sodium sulfate, potassium sulfate, magnesium sulfate, magnesium chloride, sodium chloride, zinc chloride, zinc sulfate, aluminum potassium sulfate, aluminum chloride, ferric chloride, zinc paraphenolsulfonate, and methaline. Acid salts, sodium hydrogen phosphate, aluminum hydroxychloride and the like. Salts may be formed in the system by blending them in the form of metal hydroxides such as sodium hydroxide, potassium hydroxide, lithium hydroxide and the like.

Examples of the organic metal salts include metal salts of organic acids such as lactic acid, tartaric acid, succinic acid, citric acid, aspartic acid, and benzoic acid; metal salts of hydroxy acids such as 10-hydroxyundecanoic acid; Sodium pyrrolidonecarboxylate, metal salt of dehydroacetic acid, calcium pantothenate; monovalent, divalent or trivalent metal salt of L-ascorbic acid phosphate;
Monovalent, divalent or trivalent metal salts of L-ascorbic acid sulfate; monovalent, divalent or trivalent metal salts of L-ascorbic acid.

The metal compound of the component (A) can be used alone or in combination of two or more.
~ 60% by weight, especially 0.1 ~ 40% by weight, more preferably 0.1 ~
It is preferable to add 30% by weight, especially 1 to 30% by weight.

The substituent (a) in the water-soluble polysaccharide derivative of the component (B) used in the present invention is, for example, a linear or branched alkyl, alkenyl, arylalkyl or alkyl having 8 to 40 carbon atoms. Examples thereof include an aryl group, an alkyl ether group, an alkenyl ether group, and an arylalkyl ether group. Particularly, an alkyl glyceryl ether group having a linear or branched alkyl group having 10 to 40 carbon atoms, and a linear chain having 10 to 40 carbon atoms Alternatively, an alkenyl glyceryl ether group having a branched alkenyl group is preferable. Specifically, 2-hydroxy-3-alkoxypropyl group, 2-alkoxy-1- (hydroxymethyl)
Examples include an ethyl group, a 2-hydroxy-3-alkenyloxypropyl group, and a 2-alkenyloxy-1- (hydroxymethyl) ethyl group. Examples of the alkyl or alkenyl group having 10 to 40 carbon atoms substituted on the glyceryl ether group include those having 12 to 36 carbon atoms, particularly 16 to
Twenty-four straight-chain or branched-chain alkyl and alkenyl groups are preferred, and from the viewpoint of stability, an alkyl group, particularly a straight-chain alkyl group, is preferred.

Examples of the substituent (b) include a methyl group, a hydroxyethyl group, a hydroxypropyl group, a polyoxyethylene group, a polyglycerin group, a sulfoalkyl group and the like. Among these, a sulfoalkyl group having 1 to 5 carbon atoms which may be substituted by a hydroxyl group or a salt thereof is preferable, and specifically, a 2-sulfoethyl group,
A 3-sulfopropyl group, a 3-sulfo-2-hydroxypropyl group, a 2-sulfo-1- (hydroxymethyl) ethyl group, and the like. All or a part of the sulfo groups is an alkali metal, an alkaline earth metal, It may be in the form of a salt with an organic cation group such as an amine or an ammonium ion.

The degree of substitution of the substituent (a) is preferably from 0.001 to 1, more preferably from 0.002 to 0.5, even more preferably from 0.003 to 0.1 per constituent monosaccharide residue. (B)
Is preferably 0.01 to 2.5, more preferably 0.02 to 2, further preferably 0.1 to 1.5 per constituent monosaccharide residue. The ratio of the substituent (a) to the substituent (b) is 1: 1.
It is preferably from 000 to 100: 1, in particular from 1: 500 to 10: 1, more preferably from 1: 300 to 10: 1.

The basic skeleton of the water-soluble polysaccharide derivative of the component (B) is selected from known polysaccharides, and among them, cellulose, hydroxyethyl cellulose, methyl cellulose, ethyl cellulose and hydroxypropyl cellulose are preferred. Further, the weight average molecular weight of these polysaccharides or derivatives thereof is 10,000 to 10,000,000, preferably 100,000 to
5 million, particularly preferably in the range of 300,000 to 2,000,000.

Such a water-soluble polysaccharide derivative is produced by sequentially or simultaneously introducing a hydrophobic substituent (a) and a hydrophilic substituent (b) into a polysaccharide or a derivative thereof. For example, after partially introducing a hydrophobic substituent into a hydroxyl group of a polysaccharide or a derivative thereof, or after introducing a substituent having a sulfonic acid group, all or a part of the remaining hydroxyl groups is further sulfonated or hydrophobized. Or by performing hydrophobization and sulfonation simultaneously. Among these methods, it is more preferable to perform sulfonation after hydrophobization.

Hereinafter, the hydrophobization reaction and the sulfonation reaction will be described separately. In addition, introduction of a hydrophilic group other than a sulfone group can also be performed according to the following.

<Hydrophobic Reaction> In the hydrophobizing reaction of the polysaccharide or the sulfonated polysaccharide, the polysaccharide or the sulfonated polysaccharide is dissolved or dispersed in an appropriate solvent, and a hydrophobizing agent, preferably C ₁₀ to C ₁₀ , is used.
C ₄₀ alkyl glycidyl ether and / or C ₁₀ -C ₄₀
It is carried out by reacting with alkenyl glycidyl ether.

<Sulfonation Reaction> In the sulfonation reaction of the polysaccharide or the hydrophobized polysaccharide, the polysaccharide or the hydrophobized polysaccharide is dissolved or dispersed in an appropriate solvent, and a sulfonating agent, preferably vinyl sulfonic acid, or 3-halo-2-hydroxypropanesulfonic acid, 2-halo-2- (hydroxymethyl) ethanesulfonic acid, 3-halopropanesulfonic acid,
It is carried out by reacting a halo C ₁ -C ₅ alkanesulfonic acid which may be substituted with a hydroxyl group such as 2-haloethanesulfonic acid and a salt thereof.

The water-soluble alkyl-substituted polysaccharide derivative of the component (B) can be used alone or in combination of two or more. Especially 0.01 to 10% by weight, more preferably 0.0 to 10% by weight.
It is preferable to blend 5 to 3% by weight, since a less sticky feeling and a more comfortable use feeling can be obtained.

Further, in addition to the above essential components, components commonly used in cosmetics, quasi-drugs, pharmaceuticals, and the like can be appropriately added to the cosmetic of the present invention as long as the effects are not impaired. Such components include, for example, ceramides and ceramide-like substances (for example, JP-A-8-3192).
No. 63), humectants, amino acids, plant extracts, whitening agents, anti-inflammatory agents, singlet oxygen scavengers, antioxidants,
Polysaccharides, alcohols, sterols, blood circulation promoters, purified water, ethanol, surfactants, oily components, silicones, fluorine-based oils, UV protection agents, powders, oil gelling agents,
Examples include a film forming agent, a sebum secretion inhibitor, a softener, a pH adjuster, a preservative, a sequestering agent, hydroxy acids, a dye, and a fragrance.

The cosmetic of the present invention can be used to adjust pH
It is preferably in the range of 3 to 10, especially pH 4 to 8.

The cosmetic of the present invention can be produced according to a conventional method. In addition, the cosmetic of the present invention is not limited to general skin cosmetics, but includes quasi-drugs, topical drugs, and the like, and its dosage form may be arbitrarily selected according to the purpose. Cream, ointment, emulsion, lotion, solution, gel, powder, stick, etc.

The cosmetics of the present invention may be in various forms, such as creams, cosmetic emulsions, lotions, oily cosmetics, massage cosmetics, packs, lipsticks, foundations, skin cleansers, hair tonics, hair styling agents, It can be used as cosmetics such as hair restorer and hair restorer.

The cosmetic of the present invention has a viscosity at 25 ° C. (B
L-type viscometer) is 2000 mPa · s or more, preferably 300 mPa · s or more.
0 mPa · s or more, particularly preferably 5000 to 30000 mP
a · s.

[0023]

The cosmetic of the present invention can maintain an initial viscosity of 2000 mPa · s or more even if it contains a metal compound,
Furthermore, there is no sticky feeling, the spread is good, and the usability is good. In addition, since metal compounds can be blended in high concentrations,
The functions of the compounded metal compound, such as protection against ultraviolet rays, antiseptic properties, astringency, and improvement in feel, are sufficiently exhibited. In the case of emulsified cosmetics, emulsion stability is excellent, and no separation or sedimentation of metal compounds is observed even after long-term storage.

[0024]

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples.

In the following Production Examples, the degree of substitution of the hydrophobic substituent of the water-soluble polysaccharide derivative was measured using NMR (solvent: deuterated DMSO). The substitution degree of the sulfone group was determined by a colloid titration method. That is, a thickener solution having a known concentration is prepared, and a known weight N /
A 200 methyl glycol chitosan solution (Wako Pure Chemicals, for colloid titration) was added, and a few drops of a toluidine blue indicator solution (Wako Pure Chemicals, for colloid titration) were added. This is N
Back titration was carried out with a / 400 polyvinyl potassium sulfate solution (Wako Pure Chemical Industries, for colloid titration), and the degree of substitution was calculated from the titer. In the following Production Examples, the “degree of substitution” indicates the number of substituents per constituent monosaccharide residue.

Production Example 1 (1) Hydroxyethyl cellulose having a weight average molecular weight of about 800,000 and a hydroxyethyl group substitution degree of 1.8 (HEC-
QP4400, manufactured by Union Carbide) 50 g, 88
A slurry liquid comprising 400 g of a 40% aqueous isopropyl alcohol solution and 3.5 g of a 48% aqueous sodium hydroxide solution was prepared, and stirred at room temperature for 30 minutes under a nitrogen atmosphere. After adding 5.4 g of stearyl glycidyl ether and reacting at 80 ° C. for 8 hours, the reaction solution was neutralized with acetic acid, and the reaction product was separated by filtration. After washing with acetone and drying, 49.4 g of a hydrophobized hydroxyethyl cellulose derivative was obtained.

(2) A slurry solution comprising 10.0 g of the hydrophobized hydroxyethyl cellulose derivative obtained in (1), 80.0 g of isopropyl alcohol and 0.33 g of a 48% aqueous sodium hydroxide solution was prepared, and the mixture was stirred at room temperature under a nitrogen stream. Stir for 30 minutes. To the reaction solution, sodium chloro-2-hydroxypropanesulfonate (6.4 g, 48%)
A mixed solution consisting of 2.7 g of an aqueous sodium hydroxide solution and 20.0 g of water was added, and sulfonation was performed at 50 ° C. for 9 hours. The reaction solution was neutralized with acetic acid, the product was filtered off, washed with acetone and dried to obtain 7.2 g of a water-soluble polysaccharide derivative (1) substituted with a stearyl glyceryl ether group and a sulfo-2-hydroxypropyl group. .

The degree of substitution of the stearyl glyceryl ether group in the obtained water-soluble polysaccharide derivative (1) was 0.030, and the degree of substitution of the sulfo-2-hydroxypropyl group was 0.15.

Production Examples 2 to 12 Water-soluble polysaccharide derivatives were obtained according to Production Example 1 and using the starting materials shown in Table 1.

[0030]

[Table 1]

Examples 1 to 16 and Comparative Examples 1 to 4 UV-protective emulsified cosmetics having the compositions shown in Tables 1 to 5 were produced by a conventional method. About the obtained cosmetic, initial viscosity, aging viscosity, emulsion stability, non-stickiness, good spreadability,
The overall feeling of use and the ability to protect against ultraviolet rays were evaluated. Table 2 shows the results.
6 is shown.

(Evaluation method) (1) Initial viscosity and viscosity after storage for one month at 50 ° C. (daily viscosity): After measuring the initial viscosity of the prepared cosmetic,
The sample was allowed to stand for one month under the condition of ° C., and the viscosity was measured as daily viscosity. The viscosity was measured by using a rotary viscometer (BL viscometer, manufactured by Tokyo Keiki) rotor No. 3 at 25 ° C. The results are shown based on the following criteria. A: 5000 mPa · s or more. ；: 2000 mPa · s or more and less than 5000 mPa · s. Δ: 1000 mPa · s or more and less than 2000 mPa · s. ×: less than 1000 mPa · s.

(2) Emulsion stability: Each cosmetic was prepared at 50 ° C. for 1
It was stored for months, and its condition was visually evaluated according to the following criteria. A: No change is observed in the state. ；: A slight change in the state is observed. Δ: A large change is observed in the state. X: Separation or sedimentation of metal salt is observed.

(3) Lack of stickiness, good spreadability and general feeling of use: Twenty specialized panelists used each cosmetic for two months, and the sensory evaluation was performed according to the following criteria. ◎: 16 or more of the 20 persons were judged to be good. ；: 11 to 15 persons were judged to be good among 20 persons. Δ: Out of the 20 persons, 6 to 10 persons were judged to be good. ×: Five or less out of 20 were judged to be good.

(4) UV protection ability: SPF (Sun Pr.) Was measured using an SPF analyzer (Optometrics USA, Inc.).
otection Factor) was measured. A: SPF value of 15 or more. ；: SPF value of 10 or more and less than 15. Δ: SPF value 5 or more and less than 10. X: SPF value less than 5.

[0036]

[Table 2]

[0037]

[Table 3]

[0038]

[Table 4]

[0039]

[Table 5]

[0040]

[Table 6]

From the results shown in Tables 2 to 6, all of the cosmetics of the present invention have an initial viscosity of 5,000 mPa · s or more and a daily viscosity of 5,000 mPa · s or more. System. In addition, the emulsion stability was good, and no change in the state was observed. Furthermore, high evaluations were also obtained with respect to lack of stickiness, good spreadability, and overall feeling of use. It has high UV protection and the effect of the metal compound was exhibited. In addition, as shown in Examples 1, 14 and 15, stable cosmetics were obtained regardless of the amount of the water-soluble polysaccharide derivative. As shown in Examples 1, 13 and 16, even when the amount of the metal compound was changed, a stable cosmetic was obtained by adjusting the blending amount of the water-soluble polysaccharide derivative.

Examples 17 to 20, Comparative Examples 5 to 8 Emulsified cosmetics having the compositions shown in Tables 7 and 8 were produced by a conventional method. The obtained cosmetics were evaluated for initial viscosity, change over time, emulsification stability, lack of stickiness, good spreadability, and overall feeling of use in the same manner as in Examples 1 to 16. Tables 7 and 8 show the results.
Shown in

[0043]

[Table 7]

[0044]

[Table 8]

Example 21 (Emulsion) An emulsion having the following composition was produced by a conventional method. The initial viscosity, the viscosity over time, the emulsion stability, the lack of stickiness, the good spreadability, and the feeling upon use were all good.

(Composition) (% by weight) Water-soluble polysaccharide derivative (Production Example 6) 0.25 Acrylic acid-based polymer (Carbopol 981: manufactured by BF Goodrich Co.) 0.1 Xanthan gum 0.1 Squalane 3.0 Ethanol ( 55 v / v%) 10.0 Glycerin 2.0 2-Ethylhexyl paramethoxycinnamate 3.0 Methylpolysiloxane (50cs) 5.0 Methylcyclopolysiloxane (DC246: manufactured by Toray Industries) 25.0 Zinc paraphenolsulfonate 0 0.2 Zinc oxide treated with silicone 3.0 3.0 2- (2-Hydroxyethoxy) ethylguanidine 1.0 Water balance

Example 22 (Lotion) A lotion having the following composition was produced by a conventional method. Initial viscosity, aging viscosity, appearance, lack of stickiness, good spreadability and overall feeling of use were evaluated in the same manner as in Examples 1 to 16, and as a result, initial viscosity 、, aging viscosity 、, appearance in aging changed None, no stickiness, good spreadability, and overall feeling of use were all ◎.

(Composition) (% by weight) Ethanol 5.0 Glycerin 3.0 Polyethylene glycol 1500 4.0 Polyoxyethylene oleyl ether (20EO) 0.3 Polyoxyethylene hydrogenated castor oil (30EO) 0.2 Water-soluble polysaccharide Derivative (Production Example 1) 0.15 2-Hydroxyethylguanidine 0.5 Ceramide 0.5 Zinc paraphenolsulfonate 0.2 Water balance

Example 23 (Serum) A serum having the following composition was produced by a conventional method. The initial viscosity, the viscosity over time, the emulsion stability, the lack of stickiness, the good spreadability, and the feeling upon use were all good.

(Composition) (% by weight) Poly (N-propionylethyleneimine) -modified silicone 2.0 ceramide 1.0 2- (2-hydroxyethoxy) ethylguanidine 1.0 2-ethylhexyl paramethoxycinnamate 0.3 Sugina Extract (Phyterene EG-199 <BG>: manufactured by Ichimaru Falcos) 0.5 Water-soluble polysaccharide derivative (Production Example 4) 0.3 Acrylic acid-based polymer (Pemran TR-2: BF manufactured by Goodrich) 0.05 Acrylic Acid-based polymer (Carbopol 981: BF manufactured by Goodrich) 0.05 Xanthan gum 0.1 Sodium hyaluronate 0.1 Arbutin 2.0 Sodium citrate 1.0 Acidic heteropolysaccharide (JP-A-64-10997; Example 1, the same applies hereinafter) 0.1 ethanol 5.0 1,3-butylene glycol 2.0 L-arginine 0.4 perfume 0. Water balance

Example 24 (Gel-like cosmetic) A gel-like cosmetic having the following composition was produced by a conventional method. The initial viscosity, the viscosity over time, the emulsion stability, the lack of stickiness, the good spreadability, and the feeling upon use were all good.

(Composition) (% by weight) Water-soluble polysaccharide derivative (Production Example 6) 0.5 glycerin 5.0 1,3-butylene glycol 2.0 ethanol 5.0 10-hydroxyundecanoic acid 3.0 L-arginine 2.0 Ethylparaben 0.1 Methylpolysiloxane (6cs) 2.0 Polyoxyethylene hydrogenated castor oil (40EO) 1.0 Tris (ethoxyethoxyethyl) phosphate 1.0 Sodium N-acylglutamate (Amisoft MS-11: (Ajinomoto Co.) 0.5 Acidic heteropolysaccharide 0.1 Lactic acid 0.05 Sodium lactate (50%) 1.0 Nylon powder (Toray) 1.0 Water balance

Example 25 (Sun care cream) A sun care cream having the following composition was produced by a conventional method. The initial viscosity, aging viscosity, emulsion stability, lack of stickiness, good spreadability and feeling of use were all い ず れ.

(Composition) (% by weight) Dimethylsiloxane methyl (polyoxyethylene) siloxane polymer 2.0 Polyoxyethylene (20EO) sorbitan monooleate 0.5 Methyl polysiloxane (5cs) 7.0 Methylphenyl Polysiloxane (20cs) 2.0 Jojoba oil 2.0 Dextrin palmitate 0.5 Octyldimethyl paraaminobenzoic acid 4.0 Silica, fine particles coated with alumina coated titanium oxide 3.0 Cerium oxide 1.0 Zirconium oxide 1.0 Magnesium sulfate 0.5 glycerin 5.0 dibutylhydroxytoluene 0.05 water-soluble alkyl-substituted polysaccharide derivative (Production Example 6) 0.3 water balance

Example 26 (Foundation) A foundation having the following composition was produced by a conventional method. The initial viscosity, the viscosity over time, the emulsion stability, the lack of stickiness, the good spreadability, and the feeling upon use were all good.

(Composition) (% by weight) Water-soluble polysaccharide derivative (Production Example 12) 0.5 α-monoisostearyl glyceryl ether 2.0 aluminum diisostearate 0.2 liquid paraffin 10.0 neopentyl glycol dioctanoate 5.0 Methylphenyl polysiloxane (14cs) 10.0 2-Ethylhexyl p-methoxycinnamate 3.0 2-Hydroxy-4-methoxybenzophenone 1.0 Fine particles of titanium oxide coated with perfluoroalkyl phosphate ester 5.0 Silicone Coated fine particle zinc oxide 1.0 Mica titanium 0.5 Colored titanium mica 1.5 Bengala 0.2 Yellow iron oxide 0.7 Black iron oxide 0.05 Magnesium sulfate 1.0 Methyl paraben 0.2 Fragrance Trace water Balance

Example 27 (Massage Cosmetic) A massage cosmetic having the following composition was produced by a conventional method. The initial viscosity, the viscosity over time, the emulsion stability, the lack of stickiness, the good spreadability, and the feeling upon use were all good.

(Composition) (% by weight) Water-soluble polysaccharide derivative (Production Example 4) 1.0 Sodium chloride 5.0 Zeolite 1.0 Glycerin 93.0

Example 28 (Hand cream) A hand cream having the following composition was produced by a conventional method. The initial viscosity, the viscosity over time, the emulsion stability, the lack of stickiness, the good spreadability, and the feeling upon use were all good.

(Composition) (% by weight) Squalane 15.0 Methyl polysiloxane (2cs) 5.0 Vaseline 15.0 Preservative / perfume Appropriate amount Purified water Remaining amount Glycerin 2.0 Sodium benzoate 0.3 Water-soluble polysaccharide derivative (Production Example 1) 0.5

Example 29 (Packing agent) A packing agent having the following composition was produced by a conventional method. The initial viscosity, the viscosity over time, the emulsion stability, the lack of stickiness, the good spreadability, and the feeling upon use were all good.

(Composition) (% by weight) Poly (N-propionylethyleneimine) -modified silicone 2.0 dipropylene glycol 3.0 ceramide 1.0 polyethylene glycol 3.0 1,3-butylene glycol 1.0 acrylic acid Polymer (Sepigel 305: manufactured by Sepik) 0.2 Water-soluble alkyl-substituted polysaccharide derivative (Production Example 6) 2.8 Polyvinyl alcohol 12.0 Lactic acid 0.5 Aloe extract (Aloe extract: manufactured by Maruzen Pharmaceutical Co., Ltd.) 1 acidic heteropolysaccharide 0.1 sodium citrate 1.0 glycerin 0.5 tea extract 0.5 L-arginine 0.2 ethanol 0.1 flavor 0.1 water balance

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁶ Identification symbol FI // A61K 7/035 A61K 7/035 (72) Inventor Kazuhiro Yamaki 2-1-3 Bunka, Sumida-ku, Tokyo Kao Corporation Inside the research institute (72) Inventor Mitsuharu Masuda 2-1-3 Bunka, Sumida-ku, Tokyo Inside the Kao Co., Ltd. research laboratory (72) Inventor Tomohito Kitsuki 1334 Minato, Wakayama-shi, Wakayama Pref.

Claims (5)

[Claims] Claims: 1. A composition comprising the following components (A) and (B):
A cosmetic having a viscosity at 5 ° C of 2000 mPa · s or more. (A) a metal compound selected from metal oxides, inorganic metal salts and organic metal salts, (B) a part or all of the hydrogen atoms of the hydroxyl group of the polysaccharide or a derivative thereof, Linear or branched alkyl group,
A substituent having a hydrophobic part selected from an alkenyl group, an arylalkyl group and an alkylaryl group, and (b) a hydroxyl group substituted with a substituent having an ionic or nonionic hydrophilic part which may be substituted. And the ratio of the substituent (a) to the substituent (b) is 1: 1000 to 100:
1. A water-soluble polysaccharide derivative which is 1. 2. The method according to claim 1, wherein the substituent (a) of the component (B) has 1 carbon atom.
The cosmetic according to claim 1, which is an alkyl glyceryl ether group having a linear or branched alkyl group having 0 to 40 and / or an alkenyl glyceryl ether group having a linear or branched alkenyl group having 10 to 40 carbon atoms. . 3. The cosmetic according to claim 1, wherein the substituent (b) of the component (B) is a sulfoalkyl group having 1 to 5 carbon atoms which may be substituted by a hydroxyl group, or a salt thereof. 4. The method according to claim 1, wherein the substituent (b) of the component (B) is a 2-sulfoethyl group, a 3-sulfopropyl group, or a 3-sulfo-2- group.
The cosmetic according to any one of claims 1 to 3, wherein the cosmetic is at least one selected from a hydroxypropyl group and a 2-sulfo-1- (hydroxymethyl) ethyl group. 5. Component (B) is a polysaccharide or a derivative thereof, (i) a hydrophobizing agent selected from C ₁₀ -C ₄₀ alkyl glycidyl ethers and / or C ₁₀ -C ₄₀ alkenyl glycidyl ethers, and (ii) 2.) A water-soluble polysaccharide derivative obtained by reacting a vinyl sulfonic acid, a halo C ₁ -C ₅ alkane sulfonic acid optionally substituted with a hydroxyl group and a sulfonating agent selected from salts thereof.
The cosmetic according to any one of claims 4 to 4.