JPH08505867A - 炎症治療用の可溶性補体レセプター１（ｓｃｒ−１）とアミジノフェニルまたはアミジノナフチルエステルの組み合わせ - Google Patents

炎症治療用の可溶性補体レセプター１（ｓｃｒ−１）とアミジノフェニルまたはアミジノナフチルエステルの組み合わせ

Info

Publication number
JPH08505867A
JPH08505867A JP6516809A JP51680994A JPH08505867A JP H08505867 A JPH08505867 A JP H08505867A JP 6516809 A JP6516809 A JP 6516809A JP 51680994 A JP51680994 A JP 51680994A JP H08505867 A JPH08505867 A JP H08505867A
Authority
JP
Japan
Prior art keywords
apan
amidinophenyl
treatment
soluble
brl55730
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6516809A
Other languages
English (en)
Japanese (ja)
Inventor
モサコウスカ，ダヌータ・エワ・イレナ
スミス，リチャード・アンソニー・ゴドウィン
Original Assignee
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー filed Critical スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー
Publication of JPH08505867A publication Critical patent/JPH08505867A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP6516809A 1993-01-22 1994-01-21 炎症治療用の可溶性補体レセプター１（ｓｃｒ−１）とアミジノフェニルまたはアミジノナフチルエステルの組み合わせ Pending JPH08505867A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9301289.6 1993-01-22
GB939301289A GB9301289D0 (en) 1993-01-22 1993-01-22 Novel composition
PCT/GB1994/000122 WO1994016719A1 (en) 1993-01-22 1994-01-21 Combination of a soluble complement receptor -1(scr1) and an amidinophenyl or amidino naphthyl-ester for treating inflammation

Publications (1)

Publication Number Publication Date
JPH08505867A true JPH08505867A (ja) 1996-06-25

Family

ID=10729169

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6516809A Pending JPH08505867A (ja) 1993-01-22 1994-01-21 炎症治療用の可溶性補体レセプター１（ｓｃｒ−１）とアミジノフェニルまたはアミジノナフチルエステルの組み合わせ

Country Status (10)

Country Link
EP (1) EP0680332A1 (show.php)
JP (1) JPH08505867A (show.php)
CN (1) CN1118141A (show.php)
AU (1) AU5863694A (show.php)
CA (1) CA2153797A1 (show.php)
GB (1) GB9301289D0 (show.php)
NZ (1) NZ259737A (show.php)
TW (1) TW241203B (show.php)
WO (1) WO1994016719A1 (show.php)
ZA (1) ZA94398B (show.php)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE222100T1 (de) * 1993-10-21 2002-08-15 Searle & Co Amidino-derivate nützlich als no synthase-hemmer
GB9604518D0 (en) * 1996-03-02 1996-05-01 Smithkline Beecham Plc Novel compounds
US8088386B2 (en) * 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
JP4897690B2 (ja) * 2004-10-12 2012-03-14 ジェネンテック， インコーポレイテッド 補体関連障害の予防および処置のためのＣＲＩｇポリペプチド
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions
GB2095239B (en) * 1981-02-27 1985-03-06 Torii & Co Ltd Novel amidine compounds
JPS57179147A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine derivative
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
CA2097825A1 (en) * 1990-12-06 1992-06-07 Henry C. Marsh, Jr. Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity

Also Published As

Publication number Publication date
GB9301289D0 (en) 1993-03-17
ZA94398B (en) 1994-11-15
EP0680332A1 (en) 1995-11-08
WO1994016719A1 (en) 1994-08-04
AU5863694A (en) 1994-08-15
CN1118141A (zh) 1996-03-06
CA2153797A1 (en) 1994-08-04
TW241203B (show.php) 1995-02-21
NZ259737A (en) 1997-04-24

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