ZA94398B - Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation - Google Patents

Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation

Info

Publication number
ZA94398B
ZA94398B ZA94398A ZA94398A ZA94398B ZA 94398 B ZA94398 B ZA 94398B ZA 94398 A ZA94398 A ZA 94398A ZA 94398 A ZA94398 A ZA 94398A ZA 94398 B ZA94398 B ZA 94398B
Authority
ZA
South Africa
Prior art keywords
amidinophenyl
scr1
napthyl
amidino
ester
Prior art date
Application number
ZA94398A
Inventor
Danutha Ewa Irena Mossakowska
Richard Anthony Godwin Smith
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA94398B publication Critical patent/ZA94398B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA94398A 1993-01-22 1994-01-20 Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation ZA94398B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939301289A GB9301289D0 (en) 1993-01-22 1993-01-22 Novel composition

Publications (1)

Publication Number Publication Date
ZA94398B true ZA94398B (en) 1994-11-15

Family

ID=10729169

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA94398A ZA94398B (en) 1993-01-22 1994-01-20 Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation

Country Status (10)

Country Link
EP (1) EP0680332A1 (en)
JP (1) JPH08505867A (en)
CN (1) CN1118141A (en)
AU (1) AU5863694A (en)
CA (1) CA2153797A1 (en)
GB (1) GB9301289D0 (en)
NZ (1) NZ259737A (en)
TW (1) TW241203B (en)
WO (1) WO1994016719A1 (en)
ZA (1) ZA94398B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT724435E (en) * 1993-10-21 2002-11-29 Searle & Co UTEIS AMIDINE DERIVATIVES AS NITRIC OXIDE INHIBITORS
GB9604518D0 (en) * 1996-03-02 1996-05-01 Smithkline Beecham Plc Novel compounds
US8088386B2 (en) * 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
JP4897690B2 (en) * 2004-10-12 2012-03-14 ジェネンテック， インコーポレイテッド CRIg polypeptide for prevention and treatment of complement related disorders
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions
DE3207033C2 (en) * 1981-02-27 1984-09-13 Torii & Co., Ltd., Tokyo Amidine compounds, processes for their preparation and pharmaceutical compositions containing these compounds
JPS57179147A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine derivative
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
EP0560929A1 (en) * 1990-12-06 1993-09-22 T Cell Sciences, Inc. Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity

Also Published As

Publication number Publication date
EP0680332A1 (en) 1995-11-08
GB9301289D0 (en) 1993-03-17
NZ259737A (en) 1997-04-24
TW241203B (en) 1995-02-21
CA2153797A1 (en) 1994-08-04
CN1118141A (en) 1996-03-06
JPH08505867A (en) 1996-06-25
AU5863694A (en) 1994-08-15
WO1994016719A1 (en) 1994-08-04

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