JPH08503710A - ヒドロキシカルバゾール化合物の抗酸化心臓保護的使用およびそれを使用する治療方法 - Google Patents

ヒドロキシカルバゾール化合物の抗酸化心臓保護的使用およびそれを使用する治療方法

Info

Publication number
JPH08503710A
JPH08503710A JP6513450A JP51345094A JPH08503710A JP H08503710 A JPH08503710 A JP H08503710A JP 6513450 A JP6513450 A JP 6513450A JP 51345094 A JP51345094 A JP 51345094A JP H08503710 A JPH08503710 A JP H08503710A
Authority
JP
Japan
Prior art keywords
formula
carbon atoms
hydrogen
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6513450A
Other languages
English (en)
Japanese (ja)
Inventor
バロン,フランク・シー
フュアースタイン,ジオラ
ユエ,ティエン−リ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH08503710A publication Critical patent/JPH08503710A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paper (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
JP6513450A 1992-12-01 1993-12-01 ヒドロキシカルバゾール化合物の抗酸化心臓保護的使用およびそれを使用する治療方法 Pending JPH08503710A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98391692A 1992-12-01 1992-12-01
US07/983,916 1992-12-01
PCT/US1993/011597 WO1994012177A1 (en) 1992-12-01 1993-12-01 Antioxydant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds

Publications (1)

Publication Number Publication Date
JPH08503710A true JPH08503710A (ja) 1996-04-23

Family

ID=25530177

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6513450A Pending JPH08503710A (ja) 1992-12-01 1993-12-01 ヒドロキシカルバゾール化合物の抗酸化心臓保護的使用およびそれを使用する治療方法

Country Status (9)

Country Link
US (1) US5405863A (enExample)
EP (1) EP0671913A1 (enExample)
JP (1) JPH08503710A (enExample)
KR (1) KR950703949A (enExample)
CN (1) CN1043509C (enExample)
AU (1) AU675481B2 (enExample)
CA (1) CA2150694A1 (enExample)
WO (1) WO1994012177A1 (enExample)
ZA (1) ZA938896B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000510110A (ja) * 1996-04-29 2000-08-08 スミスクライン・ビーチャム・コーポレイション 抗酸化化合物
WO1998015272A1 (en) 1996-10-09 1998-04-16 BOEHRINGER MANNHEIM PHARMACEUTICALS CORP. - SMITHKLINE BEECHAM CORPORATION, LIMITED PARTNERSHIP No.1 Method for inhibiting stress-activated protein kinases
JP4126345B2 (ja) * 1997-03-06 2008-07-30 松森  昭 ウイルス感染症の予防・治療剤
US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
AU5251999A (en) 1998-08-04 2000-02-28 Wisconsin Alumni Research Foundation Method of reducing retinal ganglion cell degeneration
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
US20050148779A1 (en) * 2002-04-30 2005-07-07 Wei Chen Carvedilol monocitrate monohydrate
US20050261355A1 (en) * 2002-06-27 2005-11-24 Sb Pharmco Puerto Rico Inc., Carvedilol hydobromide
KR101468827B1 (ko) * 2002-06-27 2014-12-03 스미스클라인 비이참 (코르크) 리미티드 카베딜롤 인산염 및(또는) 그의 용매화물, 상응하는 조성물, 및(또는) 치료 방법
US20050020666A1 (en) * 2003-07-25 2005-01-27 Dabur Research Foundation Cardioprotective agents
JP2007512350A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール組成物の治療および送達方法
EP1691789B1 (en) * 2003-11-25 2017-12-20 SmithKline Beecham (Cork) Limited Carvedilol free base, salts, anhydrous forms or solvate thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
EP1686986A4 (en) * 2003-11-25 2009-05-27 Sb Pharmco Inc CARVEDILOL SALTS, CORRESPONDING COMPOSITIONS, METHODS OF ADMINISTRATION AND / OR TREATMENT
US20090076116A1 (en) * 2007-09-13 2009-03-19 Protia, Llc Deuterium-enriched carvediolo
US10281374B2 (en) * 2015-11-04 2019-05-07 Diagnostic Biosystems Method of pretreatment of biological samples for an analyte-staining assay method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4438559A (en) * 1980-06-27 1984-03-27 Fuji Machine Mfg. Co. Ltd. Apparatus for automatically mounting non-lead electronic components on printed-circuit

Also Published As

Publication number Publication date
US5405863A (en) 1995-04-11
CN1098909A (zh) 1995-02-22
WO1994012177A1 (en) 1994-06-09
CN1043509C (zh) 1999-06-02
AU675481B2 (en) 1997-02-06
ZA938896B (en) 1994-08-01
AU5732294A (en) 1994-06-22
KR950703949A (ko) 1995-11-17
CA2150694A1 (en) 1994-06-09
EP0671913A1 (en) 1995-09-20
EP0671913A4 (enExample) 1995-10-25

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