CA2150694A1 - Antioxydant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds - Google Patents

Antioxydant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds

Info

Publication number
CA2150694A1
CA2150694A1 CA002150694A CA2150694A CA2150694A1 CA 2150694 A1 CA2150694 A1 CA 2150694A1 CA 002150694 A CA002150694 A CA 002150694A CA 2150694 A CA2150694 A CA 2150694A CA 2150694 A1 CA2150694 A1 CA 2150694A1
Authority
CA
Canada
Prior art keywords
carbon atoms
formula
compound
hydrogen
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002150694A
Other languages
English (en)
French (fr)
Inventor
Frank C. Barone
Giora Feuerstein
Tian-Li Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2150694A1 publication Critical patent/CA2150694A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paper (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
CA002150694A 1992-12-01 1993-12-01 Antioxydant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds Abandoned CA2150694A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98391692A 1992-12-01 1992-12-01
US07/983,916 1992-12-01

Publications (1)

Publication Number Publication Date
CA2150694A1 true CA2150694A1 (en) 1994-06-09

Family

ID=25530177

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002150694A Abandoned CA2150694A1 (en) 1992-12-01 1993-12-01 Antioxydant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds

Country Status (9)

Country Link
US (1) US5405863A (enExample)
EP (1) EP0671913A1 (enExample)
JP (1) JPH08503710A (enExample)
KR (1) KR950703949A (enExample)
CN (1) CN1043509C (enExample)
AU (1) AU675481B2 (enExample)
CA (1) CA2150694A1 (enExample)
WO (1) WO1994012177A1 (enExample)
ZA (1) ZA938896B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000510110A (ja) * 1996-04-29 2000-08-08 スミスクライン・ビーチャム・コーポレイション 抗酸化化合物
WO1998015272A1 (en) 1996-10-09 1998-04-16 BOEHRINGER MANNHEIM PHARMACEUTICALS CORP. - SMITHKLINE BEECHAM CORPORATION, LIMITED PARTNERSHIP No.1 Method for inhibiting stress-activated protein kinases
JP4126345B2 (ja) * 1997-03-06 2008-07-30 松森　　昭 ウイルス感染症の予防・治療剤
US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
AU5251999A (en) 1998-08-04 2000-02-28 Wisconsin Alumni Research Foundation Method of reducing retinal ganglion cell degeneration
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
US20050148779A1 (en) * 2002-04-30 2005-07-07 Wei Chen Carvedilol monocitrate monohydrate
US20050261355A1 (en) * 2002-06-27 2005-11-24 Sb Pharmco Puerto Rico Inc., Carvedilol hydobromide
KR101468827B1 (ko) * 2002-06-27 2014-12-03 스미스클라인 비이참 (코르크) 리미티드 카베딜롤 인산염 및(또는) 그의 용매화물, 상응하는 조성물, 및(또는) 치료 방법
US20050020666A1 (en) * 2003-07-25 2005-01-27 Dabur Research Foundation Cardioprotective agents
JP2007512350A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール組成物の治療および送達方法
EP1691789B1 (en) * 2003-11-25 2017-12-20 SmithKline Beecham (Cork) Limited Carvedilol free base, salts, anhydrous forms or solvate thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
EP1686986A4 (en) * 2003-11-25 2009-05-27 Sb Pharmco Inc CARVEDILOL SALTS, CORRESPONDING COMPOSITIONS, METHODS OF ADMINISTRATION AND / OR TREATMENT
US20090076116A1 (en) * 2007-09-13 2009-03-19 Protia, Llc Deuterium-enriched carvediolo
US10281374B2 (en) * 2015-11-04 2019-05-07 Diagnostic Biosystems Method of pretreatment of biological samples for an analyte-staining assay method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4438559A (en) * 1980-06-27 1984-03-27 Fuji Machine Mfg. Co. Ltd. Apparatus for automatically mounting non-lead electronic components on printed-circuit

Also Published As

Publication number Publication date
US5405863A (en) 1995-04-11
CN1098909A (zh) 1995-02-22
WO1994012177A1 (en) 1994-06-09
CN1043509C (zh) 1999-06-02
AU675481B2 (en) 1997-02-06
ZA938896B (en) 1994-08-01
JPH08503710A (ja) 1996-04-23
AU5732294A (en) 1994-06-22
KR950703949A (ko) 1995-11-17
EP0671913A1 (en) 1995-09-20
EP0671913A4 (enExample) 1995-10-25

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead