JPH08501799A - アレルゲン特異的ＩｇＡモノクローナル抗体及びアレルギー治療のための関連物質 - Google Patents
アレルゲン特異的ＩｇＡモノクローナル抗体及びアレルギー治療のための関連物質Info
- Publication number
- JPH08501799A JPH08501799A JP6515422A JP51542294A JPH08501799A JP H08501799 A JPH08501799 A JP H08501799A JP 6515422 A JP6515422 A JP 6515422A JP 51542294 A JP51542294 A JP 51542294A JP H08501799 A JPH08501799 A JP H08501799A
- Authority
- JP
- Japan
- Prior art keywords
- allergen
- specific
- iga
- igg
- allergic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99412692A | 1992-12-21 | 1992-12-21 | |
| US07/994,126 | 1992-12-21 | ||
| PCT/US1993/012501 WO1994014475A1 (fr) | 1992-12-21 | 1993-12-20 | ANTICORPS MONOCLONAUX D'IgA SPECIFIQUES DE L'ALLERGENE ET PRODUITS APPARENTES POUR LE TRAITEMENT DES ALLERGIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH08501799A true JPH08501799A (ja) | 1996-02-27 |
Family
ID=25540310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6515422A Pending JPH08501799A (ja) | 1992-12-21 | 1993-12-20 | アレルゲン特異的ＩｇＡモノクローナル抗体及びアレルギー治療のための関連物質 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5670626A (fr) |
| EP (1) | EP0675734A4 (fr) |
| JP (1) | JPH08501799A (fr) |
| AU (1) | AU5958494A (fr) |
| WO (1) | WO1994014475A1 (fr) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003534290A (ja) * | 2000-05-26 | 2003-11-18 | シムフォゲン アクティーゼルスカブ | アレルギー治療用の組換えまたは精製ポリクロナール抗体 |
| JP2011084578A (ja) * | 1999-01-05 | 2011-04-28 | Fliners Univ Of South Australia | 眼障害を治療及び診断するための新規な薬物及び方法 |
| JP2015110586A (ja) * | 2007-07-09 | 2015-06-18 | ネステク ソシエテ アノニム | 環境アレルゲンによって引き起こされるアレルギーを軽減する方法 |
| US9388236B2 (en) | 2007-07-09 | 2016-07-12 | Nestec Sa | Methods for reducing allergies caused by environmental allergens |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1015493A1 (fr) | 1997-01-10 | 2000-07-05 | EPIcyte Pharmaceutical, Inc. | Nouvel agent ciblant un tissu epithelial |
| US6045774A (en) * | 1997-01-10 | 2000-04-04 | Epicyte Pharmaceutical Inc. | J chain polypeptide targeting molecule linked to an imaging agent |
| IT1289608B1 (it) * | 1997-02-05 | 1998-10-15 | Angelini Ricerche Spa | Composizione per uso terapeutico o diagnostico somministrabile per via intranasale,sublinguale o vaginale |
| US6251392B1 (en) | 1997-10-20 | 2001-06-26 | Epicyte Pharmaceuticals, Inc. | Epithelial cell targeting agent |
| US6734287B1 (en) * | 1998-04-09 | 2004-05-11 | Idexx Laboratories, Inc. | Specific binding proteins for treating canine allergy |
| US7393529B2 (en) * | 1998-04-09 | 2008-07-01 | Idexx Laboratories, Inc. | Methods and compositions for inhibiting binding of IgE to a high affinity receptor |
| WO2000027795A1 (fr) | 1998-11-12 | 2000-05-18 | Invitrogen Corporation | Reactifs de transfection |
| JP2004538237A (ja) * | 1998-12-18 | 2004-12-24 | シーア ファーマスーティカルズ エルエルシー | 表面アレルゲンに対するアレルギー反応を減少させるための方法および組成物 |
| AU775778B2 (en) * | 1999-01-05 | 2004-08-12 | Flinders University Of South Australia, The | Novel agents and methods for treatment and diagnosis of ocular disorders |
| US20030149113A1 (en) * | 2001-10-12 | 2003-08-07 | Caplan Michael J. | Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease |
| US20040266883A1 (en) * | 1999-10-27 | 2004-12-30 | Yale University | Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease |
| US20030236300A1 (en) * | 1999-10-27 | 2003-12-25 | Yale University | Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease |
| US20020132770A1 (en) * | 1999-10-27 | 2002-09-19 | Caplan Michael T. | Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease |
| US6849259B2 (en) | 2000-06-16 | 2005-02-01 | Symphogen A/S | Polyclonal antibody composition for treating allergy |
| US6932967B2 (en) * | 2001-03-22 | 2005-08-23 | Michael R. Simon | Human medical treatment by aerosol inhalation of immunoglobulin A |
| EP1877446A1 (fr) * | 2005-03-02 | 2008-01-16 | Polyrizon Ltd. | Procede de retrait de toxines de membranes mucosales |
| WO2008064031A2 (fr) * | 2006-11-13 | 2008-05-29 | Government Of The United States, As Represented Bythe Secretary Of The Department Of Health And Human Services | Puissante activation de cellules présentant des antigènes par le récepteur cellulaire 1 du virus de l'hépatite a et son rôle dans la régulation de la réponse immunitaire |
| US8709413B2 (en) | 2006-12-13 | 2014-04-29 | Michael R. Simon | Treatment of celiac disease with IgA |
| JO3820B1 (ar) * | 2012-05-03 | 2021-01-31 | Regeneron Pharma | أجسام مضادة بشرية لـ fel d1وطرق لاستخدامها |
| EP3036543B1 (fr) | 2013-08-23 | 2019-06-19 | Regeneron Pharmaceuticals, Inc. | Tests diagnostiques et méthodes pour évaluer l'innocuité, l'efficacité ou le résultat d'une immunothérapie spécifique de l'allergène (its) |
| WO2016011203A1 (fr) | 2014-07-15 | 2016-01-21 | Life Technologies Corporation | Compositions comprenant des agrégats lipidiques et procédés d'administration efficace de molécules dans des cellules |
| US11352417B2 (en) | 2016-12-22 | 2022-06-07 | Regeneron Pharmaceuticals, Inc. | Method of treating an allergy with allergen-specific monoclonal antibodies |
| JP6963036B2 (ja) | 2017-06-01 | 2021-11-05 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | Ｂｅｔ ｖ １に対するヒト抗体およびその使用方法 |
| IL299207A (en) | 2020-07-01 | 2023-02-01 | Regeneron Pharma | Methods of allergy treatment using anti-BET V 1 antibodies |
| WO2022046925A1 (fr) | 2020-08-26 | 2022-03-03 | Regeneron Pharmaceuticals, Inc. | Méthode de traitement d'une allergie à l'aide d'anticorps monoclonaux spécifiques pour allergènes |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO132132C (fr) * | 1968-10-10 | 1975-09-24 | David George Marsh | |
| JPS56145222A (en) * | 1980-04-28 | 1981-11-11 | Toshiyuki Hamaoka | Improved antibody and its preparation |
| US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US5026545A (en) * | 1984-09-17 | 1991-06-25 | Baxter International, Inc. | Treatment of allergy and composition therefor |
| US4861579A (en) * | 1988-03-17 | 1989-08-29 | American Cyanamid Company | Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies |
| CN1057785A (zh) * | 1990-04-16 | 1992-01-15 | 哈佛大学校长及研究员协会 | 合成多聚免疫球蛋白受体，受体-抗体复合物，生产及应用 |
| JP2516842B2 (ja) * | 1991-02-06 | 1996-07-24 | アサヒビール株式会社 | ダニ抗原に対するモノクロ―ナル抗体とその利用 |
| US5169627A (en) * | 1991-10-28 | 1992-12-08 | Mount Sinai School Of Medicine Of The City University Of New York | Oral pharmaceutical composition containing a polyethylene glycol-immunoglobulin G conjugate for reconstitution of secretory immunity and method of reconstituting secretory immunity |
| FR2684384B1 (fr) * | 1991-12-03 | 1995-05-12 | Fondation Nale Transfusion San | Anticorps anti-allergenes, procede de purification de ces anticorps et composition pharmaceutique les contenant. |
| CA2131898A1 (fr) * | 1992-03-10 | 1993-09-16 | Vera S. Byers | Methodes et compositions pour la modulation de la reponse immunitaire de l'hote aux allergenes |
-
1993
- 1993-12-20 AU AU59584/94A patent/AU5958494A/en not_active Abandoned
- 1993-12-20 EP EP94905492A patent/EP0675734A4/fr not_active Withdrawn
- 1993-12-20 JP JP6515422A patent/JPH08501799A/ja active Pending
- 1993-12-20 WO PCT/US1993/012501 patent/WO1994014475A1/fr not_active Application Discontinuation
-
1994
- 1994-06-21 US US08/263,258 patent/US5670626A/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011084578A (ja) * | 1999-01-05 | 2011-04-28 | Fliners Univ Of South Australia | 眼障害を治療及び診断するための新規な薬物及び方法 |
| JP2013256541A (ja) * | 1999-01-05 | 2013-12-26 | Fliners Univ Of South Australia | 眼障害を治療及び診断するための新規な薬物及び方法 |
| JP2003534290A (ja) * | 2000-05-26 | 2003-11-18 | シムフォゲン アクティーゼルスカブ | アレルギー治療用の組換えまたは精製ポリクロナール抗体 |
| JP2015110586A (ja) * | 2007-07-09 | 2015-06-18 | ネステク ソシエテ アノニム | 環境アレルゲンによって引き起こされるアレルギーを軽減する方法 |
| US9388236B2 (en) | 2007-07-09 | 2016-07-12 | Nestec Sa | Methods for reducing allergies caused by environmental allergens |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994014475A1 (fr) | 1994-07-07 |
| EP0675734A1 (fr) | 1995-10-11 |
| AU5958494A (en) | 1994-07-19 |
| US5670626A (en) | 1997-09-23 |
| EP0675734A4 (fr) | 1997-05-07 |
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