JPH0840836A - Hair-tonic and hair-growing agent - Google Patents

Abstract

PURPOSE:To increase an apparent hair volume with high durability sustaining the hair-tonic and hair-growing effect by using a combination of a blood circulation accelerator with an organic solvent and a specific fatty acid or its salt. CONSTITUTION:This hair-tonic and hair-growing agent comprises a blood circulation accelerator, an organic solvent (particularly ethanol, or a combination thereof with another organic solvent), a 12-40C straight or branched alkyl or alkenyl fatty acid or its salt. This agent has preferably a pH of 2-11. Further, it is preferred that an organic acid or its salt is admixed. The fatty acid is, for example, lauric acid, tridecanoic acid, myristic acid or the like. The organic acid is citric acid or glycolic acid or the like. This hair-tonic and hair-growing agent can develop blood circulation acceleration effect to suppress depilation and progress of the depilation stage. In addition to this effect, the fatty acid or its salt can give low elastic hairs elasticity and stiffness and develop an action to increase the apparent hair volume.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION The present invention relates to a hair nourishing and hair-growth agent having an excellent cosmetic effect on hair, in addition to a hair-growth and hair-growth effect, by increasing the apparent amount of hair by giving a hair or a strainer to the hair. Regarding

[0002]

2. Description of the Related Art Conventionally, hair nourishing and hair-growth agents include synthetic or natural drugs having a blood circulation promoting action, such as vitamin E.
Alternatively, a derivative thereof, nicotinic acid or a derivative thereof, assembly extract, etc. are blended. These drugs are, for example,
It has been clinically confirmed that it acts effectively on alopecia because it acts on the vascular nervous system to expand capillaries and improve peripheral blood flow. However, such conventional hair nourishing and hair-growth agents have a slow-acting effect on alopecia, and it takes a certain period of use for the effects to be exhibited, and naturally there are individual differences in that period as well. It may be long-term. For this reason, some people suffer from hair loss and thinning hair for a considerably long period of time, and hair loss and thinning hair become more prominent particularly in the case of people with low elasticity hair whose hair becomes thin and soft as the hair removal stage progresses. The problem becomes even more serious.

However, conventional hair nourishing and hair-growth agents are only for the purpose of imparting hair-growth and hair-growth effects, and have taken into consideration the cosmetic effect on hair until the hair-growth and hair-growth effects are exhibited and thereafter. Is not yet known. On the other hand, a hair cosmetic composition containing a specific aromatic alcohol, a fatty acid having a linear or branched alkyl group or alkenyl group having 12 to 40 carbon atoms or a salt thereof, and a cationic surfactant (JP-A-6-87724). ) And the like which impart elasticity to the hair, but these do not have hair-growth and hair-growth effects, and cannot fundamentally improve hair loss.

[0004]

As described above, the conventional hair-growth and hair-growth products are intended to impart a hair-growth and hair-growth effect, and the user is required until the effect is exhibited. Those having a cosmetic effect capable of reducing the hair loss feeling and thinning hair feeling are not yet known.

Therefore, the present invention can increase the apparent amount of hair while maintaining the hair nourishing and hair-growth effects of the conventional hair nourishing and hair-growth agent, and until the above-mentioned effects are exhibited, and even after the expression. It is an object of the present invention to provide a hair nourishing / hair-growth material capable of imparting a cosmetic effect to hair.

[0006]

Means for Solving the Problems As a result of intensive studies to achieve the above object, the present inventors have found that if a blood circulation promoter, an organic solvent and a specific fatty acid or a salt thereof are used in combination, The hair-growth effect is continuously exerted without being hindered,
In addition, the cosmetic effect of increasing the apparent amount of hair can also be exhibited, and as a result, a hair loss feeling (thinning hair feeling) from the start of use, which could not be improved by conventional hair nourishing and hair growth agents, can be achieved. The present invention was completed by finding that a hair / hair-growth material can be obtained.

That is, the present invention provides (A) a blood circulation promoting agent,
(B) An organic solvent and (C) A fatty acid or a salt thereof having a linear or branched alkyl group or alkenyl group having 12 to 40 carbon atoms, or a salt thereof is provided. is there.

The blood circulation promoter of the component (A) used in the present invention has a hair nourishing / hair-growth effect by the action of local stimulation, hair follicle activation, anti-inflammatory, etc., in addition to promoting blood circulation, and is a synthetic or natural product. Any of the above may be used. Such blood circulation promoters include dl-α-tocopherol acetate, dicaprylic acid pyridoxine, biotin, nicotinic acid and its derivatives (nicotinic acid benzyl ester), tolazoline hydrochloride, glycyrrhetinic acid glyceryl, cembly extract, Hypericum perforatum extract, Touki extract , Senkyu extract, capsicum tincture, and the like. Among these, dl-α-tocopherol acetate acetate, nicotinic acid and its derivatives, senburi extract, Hypericum perforatum extract, capsicum tincture are preferred. These blood circulation promoters are 1 type or 2 types.
A combination of two or more species can be used.

The blood circulation accelerating agent of the component (A) is preferably contained in the hair nourishing and hair-restoring agent in an amount of 0.001 to 5% by weight, and particularly 0.01 to 3% by weight causes discomfort during use. It is preferable since it can provide a sufficient blood circulation promoting effect.

As the organic solvent as the component (B) used in the present invention, a compound represented by the following formula (1), an N-alkylpyrrolidone represented by the following formula (2) or an alkylene carbonate having 1 to 4 carbon atoms is preferable. It is mentioned as a thing.

[0011]

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Specific examples of these organic solvents (B) include, for example, ethanol, isopropanol, n-propanol, n-butanol, isobutanol, ethylene glycol, propylene glycol, 1,3-butanediol, benzyl alcohol, cinnamyl. Alcohol, phenethyl alcohol, p-anisyl alcohol, p-methylbenzyl alcohol, phenoxyethanol, 2-
Benzyloxyethanol, methyl carbitol, ethyl carbitol, propyl carbitol, butyl carbitol, triethylene glycol monoethyl ether,
Triethylene glycol monobutyl ether, glycerin, N-methylpyrrolidone, N-octylpyrrolidone,
N-lauryl pyrrolidone etc. can be mentioned, and these organic solvents can be used individually or in combination of 2 or more types.

Of these organic solvents, especially ethanol, benzyl alcohol, benzyloxyethanol,
Ethyl carbitol is preferred, and when two or more kinds are used in combination, the combination of ethanol and another organic solvent such as benzyl alcohol, benzyloxyethanol, ethyl carbitol is used as the component (C) hair. It is preferable because it can promote penetration into the interior.

The organic solvent as the component (B) is preferably added to the hair-growth / hair-growth agent in an amount of 0.5 to 70% by weight, particularly 1 to 6
The blending amount of 0% by weight is preferable because the component (C) can sufficiently permeate into the hair. Further, in the hair nourishing and hair-growing material of the present invention, when ethanol is used alone as the organic solvent for the component (B), the total amount of the composition is 20
70 wt% is particularly preferable, and when 0.1 to less than 20 wt% is added, other organic solvent is added in an amount of 0.5 to 2
It is preferable to use a combination of 0% by weight.

The component (C) used in the present invention has 1 carbon atom.
Examples of the fatty acid having 2 to 40 linear or branched alkyl or alkenyl groups or salts thereof include lauric acid, tridecanoic acid, myristic acid, pentadecanoic acid, palmitic acid, heptadecanoic acid, stearic acid, nonadecanoic acid and icosane. Acid, henicosanoic acid, behenic acid,
Lignoceric acid, serotic acid, montanic acid, melissic acid, lacceronic acid, gedic acid, lauroic acid, myristoleic acid, palmitoleic acid, oleic acid, gadoleic acid, erucic acid, linoleic acid, linolenic acid, 2-heptylundecanoic acid, 2 -Isoheptyl isoundecanoic acid,
Isostearic acid (for example, manufactured by Emery Industries, Inc., Union Camp Corporation),
18-methylicosanoic acid, 2-octylarachidic acid, 2
-Methylstearic acid, 2-decyldodecanoic acid, 2-dodecyltetradecanoic acid, 2-tetradecylhexadecanoic acid, 2-hexadecyloctadecanoic acid, 2-octadecylicosanoic acid, 3-pentyloctanoic acid, 3-heptyldecanoic acid, 3 Examples thereof include nonyldodecanoic acid, 3-undecyltetradecanoic acid, 3-tridecylhexadecanoic acid, 2-octyldodecanoic acid, 2-pentylnonanoic acid, 2-hexyldecanoic acid, and 12-hydroxystearic acid. Also, as these salts, sodium,
Alkali metal salts such as lithium and potassium, calcium,
Examples thereof include alkaline earth metal salts such as magnesium, organic amine salts such as ammonia, triethanolamine, diethanolamine and monoethanolamine, and basic amino acid salts such as lysine and histidine.

Of these, fatty acids having a linear or branched alkyl or alkenyl group having 18 to 25 carbon atoms or salts thereof, particularly icosanoic acid, henicosanoic acid, behenic acid, lignoceric acid, 2-heptylundecanoic acid, 2-
Isoheptyl isoundecanoic acid, isostearic acid, 1
8-methylicosanoic acid, 2-methylstearic acid, 3-
Nonyldodecanoic acid, 3-undecyltetradecanoic acid and salts thereof are preferred. The fatty acid or its salt as the component (C) can be used alone or in combination of two or more.

The fatty acid or salt thereof as the component (C) is preferably added in the hair nourishing and hair-restoring agent in an amount of 0.001 to 10% by weight, and particularly 0.01 to 1% by weight does not impair the feel of the hair. It is preferable because the apparent hair amount can be increased.

In the hair nourishing and hair-restoring agent of the present invention, the pH of component (B) can be adjusted by adding an acid such as organic acid or phosphoric acid or an alkali such as ammonia or organic amine to adjust the pH to 2-11. It is preferable because it can easily penetrate into the hair and expand the hair to increase the apparent hair amount.

The above-mentioned organic acids include citric acid, glycolic acid, succinic acid, tartaric acid, lactic acid, acetic acid, fumaric acid, malic acid, levulinic acid, butyric acid, valeric acid, oxalic acid, maleic acid, phthalic acid, mandelic acid. Etc. Examples of the organic amine include monoethanolamine, diethanolamine, triethanolamine, aminohydroxymethylpropanediol, 2-amino-2-methyl-1.
-Propanol, 2-amino-2-methyl-1,3-propanediol, and basic amino acids such as arginine. In this case, when adjusting the pH with acid, adjust the pH to 2-5, and adjust the pH with alkali.
When adjusting, it is preferable to adjust to 8 to 11. In this case, the acid or alkali is added in an amount required to adjust the pH range, usually 0.05 to 10% by weight, but the effect of the component (B) can be obtained without impairing the feel of the hair. It is preferable because it can be sufficiently exhibited.

The hair-growth / hair-growth material of the present invention may contain an organic acid or a salt thereof within a range capable of maintaining the above pH range to form a buffer system in the hair-growth / hair-growth material. This can further enhance the effect of penetrating the component (B) into the hair. As the organic acid or its salt, lactic acid, citric acid,
And their sodium salts, potassium salts, ammonium salts and the like. These organic acids or salts thereof are preferably added to the hair nourishing / hair-growth agent in an amount of 0.05 to 10% by weight.

The hair nourishing and hair-restoring agent of the present invention may further contain, if necessary, an oily base, an emollient agent, a gelling agent, various emulsifiers, perfumes, para-hydroxybenzoic acid ester, etc. Antiseptics, antioxidants such as butylhydroxyanisole, colorants such as dyes, cooling agents such as menthol, bactericides such as hinokitiol, wetting agents such as propylene glycol, antidandruff agents such as piroctone auramine, water, etc. Can be appropriately blended within a range that does not impair the effects of the present invention.

[0022]

EFFECTS OF THE INVENTION The hair nourishing and hair-restoring agent of the present invention contains, in addition to a blood circulation promoter and an organic solvent, a fatty acid having a C 12 to C 40 linear or branched alkyl group or an alkenyl group or a salt thereof. are doing. Therefore, the blood circulation promoting effect is exerted by the blood circulation promoting agent, so that a hair loss suppressing effect can be obtained.
The progress of the hair removal stage can be suppressed. Further, in addition to such an effect, since the low-elasticity hair is provided with a lint and a strain by the fatty acid or the salt thereof, the apparent hair amount can be increased. Therefore, the hair nourishing and hair-restoring agent of the present invention can provide a cosmetic effect that the apparent hair amount can be continuously increased from the beginning of use, and this cosmetic effect suppresses the progress of the hair removal stage. It is more prominently accompanied (ie, as the number of hair loss decreases).

[0023]

EXAMPLES The present invention will be described in more detail with reference to examples below, but the present invention is not limited thereto.

Example 1 and Comparative Examples 1 to 3 Hair nourishing and hair-growth compositions having the compositions shown in Table 1 were produced by a conventional method, and their apparent improvement in hair amount and the number of hair loss during washing were tested. The test method is as follows. The results are shown in Table 1.

(Test Method) (1) Visual Improvement of Hair Volume A man who has a large number of hair loss during washing and has a slightly thinned hair 2
0 persons were divided into 4 groups of 5 persons, and Example 1 was performed for each group.
And each hair-growth and hair-growth material of Comparative Examples 1-3 was used. The amount used once was 2 ml and was applied to the scalp and hair twice a day. Two weeks and four weeks after the start of application, the visual condition of the hair in each test group was visually evaluated by two specialized panelists and the degree of improvement in the apparent hair amount was determined. The evaluation criteria are as follows.

○: 3 out of 5 subjects, both panelists
It was judged that more than one person seemed to have an increased amount of hair than before application. Δ: One of the panelists judged that 3 or more out of 5 subjects seemed to have increased hair amount before application. X: Two out of five subjects judged that the amount of hair seemed to increase more than before application, both of the panelists.

(2) Number of Hair Loss at the Time of Washing In parallel with the test of the apparent degree of improvement in the amount of hair, washing the hair (once a day,
The hair was washed with a commercially available shampoo), the number of hair loss in that case was measured, and the average number of hairs in each group was calculated.

[0028]

[Table 1]

As is clear from Table 1, in the case of Example 1, the number of hair loss was 129 after 4 weeks, which was the largest decrease (-34) compared with 163 before use, and the appearance was also apparent. The effect of increasing the amount of hair is also sufficient, and this effect is 2
As is clear from the comparison between the weeks after and 4 weeks, it was further increased as the number of hair loss decreased. These effects of Example 1 were also apparent from the increase in the number of hair loss (+7) and the apparent improvement in the amount of hair in the case of Comparative Example 3 serving as a control. On the other hand, in the case of Comparative Example 1 which did not contain the component (C), the number of hair loss was decreased as compared with that before use (-2
8), there was no change in the apparent hair amount, and in the case of Comparative Example 2 which did not contain the component (A), the apparent hair amount increased, but the number of hair loss was almost unchanged compared to before use. (-5).

Examples 2 to 5 Each hair nourishing and hair-growth agent having the composition shown in Table 2 was produced by a conventional method,
The same test as in Example 1 was performed.

[0031]

[Table 2]

Each of the hair nourishing and hair-growing agents of Examples 2 to 5 was
The number of hair loss is reduced by 30 or more on average compared to before use,
The degree of improvement due to the increase in the apparent hair amount was also remarkable.

Claims (4)

[Claims] 1. A method comprising (A) a blood circulation promoter, (B) an organic solvent, and (C) a fatty acid having a linear or branched alkyl group or alkenyl group having 12 to 40 carbon atoms or a salt thereof. Hair restoration and hair restoration material. 2. The hair nourishing / hair-growth material according to claim 1, wherein the organic solvent is ethanol or a combination of ethanol and another organic solvent. 3. The hair nourishing / hair-growth material according to claim 1, which has a pH in the range of 2-11. 4. The hair nourishing / hair-growth material according to claim 1, further comprising an organic acid or a salt thereof.