JPH07504405A - 置換アザスピラン化合物の投与によるｈｉｖ個体ａｉｄｓの遅延方法 - Google Patents

置換アザスピラン化合物の投与によるｈｉｖ個体ａｉｄｓの遅延方法

Info

Publication number
JPH07504405A
JPH07504405A JP5514099A JP51409993A JPH07504405A JP H07504405 A JPH07504405 A JP H07504405A JP 5514099 A JP5514099 A JP 5514099A JP 51409993 A JP51409993 A JP 51409993A JP H07504405 A JPH07504405 A JP H07504405A
Authority
JP
Japan
Prior art keywords
compound
formula
pharmaceutically acceptable
hydrate
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5514099A
Other languages
English (en)
Japanese (ja)
Inventor
バッジャー，アリソン・メアリー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH07504405A publication Critical patent/JPH07504405A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP5514099A 1992-01-28 1993-01-27 置換アザスピラン化合物の投与によるｈｉｖ個体ａｉｄｓの遅延方法 Pending JPH07504405A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9201804.3 1992-01-28
GB929201804A GB9201804D0 (en) 1992-01-28 1992-01-28 Methods
PCT/US1993/000712 WO1993015735A1 (en) 1992-01-28 1993-01-27 (non descriptive)-a method for delaying hiv individual aids by administration of substituted azaspirane compounds

Publications (1)

Publication Number Publication Date
JPH07504405A true JPH07504405A (ja) 1995-05-18

Family

ID=10709399

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5514099A Pending JPH07504405A (ja) 1992-01-28 1993-01-27 置換アザスピラン化合物の投与によるｈｉｖ個体ａｉｄｓの遅延方法

Country Status (5)

Country Link
EP (1) EP0727993A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH07504405A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU3594293A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB9201804D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1993015735A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT100566B (pt) * 1991-06-07 1999-06-30 Smithkline Beecham Corp Azaspiranos imunomoduladores, composicoes farmaceuticas que os contem, sua preparacao e seu uso
GB9315340D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315351D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315306D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
ZA921120B (en) * 1991-02-19 1993-01-27 Smithkline Beecham Corp Cytokine inhibitors
PT100566B (pt) * 1991-06-07 1999-06-30 Smithkline Beecham Corp Azaspiranos imunomoduladores, composicoes farmaceuticas que os contem, sua preparacao e seu uso

Also Published As

Publication number Publication date
AU3594293A (en) 1993-09-03
GB9201804D0 (en) 1992-03-11
WO1993015735A1 (en) 1993-08-19
EP0727993A1 (en) 1996-08-28
EP0727993A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1996-10-02

Similar Documents

Publication Publication Date Title
AU619780B2 (en) Immunomodulatory azaspiranes
CZ296163B6 (cs) Karboxyamidy chinolinu jako inhibitory TNF a inhibitory PDE-IV
JP4109718B2 (ja) アセチルコリンエステラーゼ阻害剤および鎮痛剤としてのイサチン誘導体
US3996214A (en) 5-(1,1-Diphenyl-4-(cyclic amino) but-2-trans-en-1-yl)-2-alkyl-1,3,4-oxadiazoles and intermediates thereto
HUP0302193A2 (hu) 1,4-Diazabiciklo[3.2.2]nonán-benzoxazol,-benzotiazol és -benzimidazol-származékok, előállításuk és ezeket tartalmazó gyógyszerkészítmények
EP0140070A1 (de) Neue Pyridoindolderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
HU197842B (en) Process for producing pharmaceutical compositions comprising 2-alkoxy-n-(1-azabicyclo/2.2.2/oct-3-yl)-benzamide derivatives
JPH05504358A (ja) 置換尿素化合物及びそれらの製法及び使用
RU2138501C1 (ru) Имидазопиридиназолидиноны, их соли и лекарственное средство
JPH07504405A (ja) 置換アザスピラン化合物の投与によるｈｉｖ個体ａｉｄｓの遅延方法
EP0587800B1 (en) Immunomodulatory azaspiranes
US3501484A (en) Certain substituted 3 - (2-indolyl)-1,2,5,6-tetrahydropyridines and derivatives thereof
WO1995003048A1 (en) Anti-hiv azaspiranes
WO1995003046A1 (en) A method of inhibiting the production of hiv
JPH07500595A (ja) アザスピラン類を用いる高脂血症の治療方法
WO1995003047A1 (en) Human immunodeficiency virus treatments
RU2745985C1 (ru) Антикоронавирусный терапевтический агент - замещенный 7-гидрокси-3,4,12,12а-тетрагидро-1H-[1,4]оксазино[3,4-c]пиридо[2,1-f][1,2,4]триазин-6,8-дион для профилактики и лечения COVID-19
WO2010074607A2 (ru) Действующее вещество и фармацевтическая композиция для лечения алкогольной зависимости, способ получения и применения
US5591748A (en) Immunomodulatory azaspiranes
FI88039C (fi) Foerfarande foer framstaellning av 2,3-dihydro-1-(8-metyl-1,2,4-triatsolo/4,3-b/pyridazin-6-yl)-4(1h)-pyridinon
JPS63150224A (ja) 脳機能改善薬
US5455247A (en) Methods for the treatment of hyperlipidemia using azaspiranes
RU2043991C1 (ru) Дигидробензофурановые карбоксамиды или его фармацевтически приемлемые соли и способ их получения
JPH10503492A (ja) 方 法
JPH0688974B2 (ja) ２−ピリジルアセタミド誘導体、その製法および用途