JPH07504205A - 神経保護及び神経調節の薬剤としての繊維芽細胞増殖因子の使用 - Google Patents

神経保護及び神経調節の薬剤としての繊維芽細胞増殖因子の使用

Info

Publication number
JPH07504205A
JPH07504205A JP6512718A JP51271894A JPH07504205A JP H07504205 A JPH07504205 A JP H07504205A JP 6512718 A JP6512718 A JP 6512718A JP 51271894 A JP51271894 A JP 51271894A JP H07504205 A JPH07504205 A JP H07504205A
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
acidic
fgfs
fibroblast growth
growth factors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6512718A
Other languages
English (en)
Japanese (ja)
Inventor
ヒメネス　ガリェゴ　ギリエルモ
サンチェス　ペドロ　クエヴァス
Original Assignee
ベーリンガー　インゲルハイム　エスパーナ　ソシエダッド　アノニマ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ベーリンガー　インゲルハイム　エスパーナ　ソシエダッド　アノニマ filed Critical ベーリンガー　インゲルハイム　エスパーナ　ソシエダッド　アノニマ
Publication of JPH07504205A publication Critical patent/JPH07504205A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP6512718A 1992-11-23 1993-11-19 神経保護及び神経調節の薬剤としての繊維芽細胞増殖因子の使用 Pending JPH07504205A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES09202360A ES2061380B1 (es) 1992-11-23 1992-11-23 Empleo del factor de crecimiento fibroblastico y sus derivados como neuroprotectores y neuromoduladores.
ES9202360 1992-11-23
PCT/EP1993/003234 WO1994012201A1 (en) 1992-11-23 1993-11-19 Use of fibroblast growth factors as neuroprotective and neuromodulatory agents

Publications (1)

Publication Number Publication Date
JPH07504205A true JPH07504205A (ja) 1995-05-11

Family

ID=8278876

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6512718A Pending JPH07504205A (ja) 1992-11-23 1993-11-19 神経保護及び神経調節の薬剤としての繊維芽細胞増殖因子の使用

Country Status (5)

Country Link
EP (1) EP0624094A1 (es)
JP (1) JPH07504205A (es)
CA (1) CA2127537A1 (es)
ES (1) ES2061380B1 (es)
WO (1) WO1994012201A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5831117A (en) 1995-01-20 1998-11-03 G. D. Searle & Co. Method of preparing retroviral protease inhibitor intermediates
DE69634907T2 (de) * 1995-04-25 2006-05-18 Ajinomoto Co., Inc. Fibroblastenwachstumsfragmente
ES2201287T5 (es) * 1996-03-22 2007-10-16 Curis, Inc. Metodo para mejorar la recuperacion funcional de la coordinacion motora, del habla o la percepcion sensorial tras una isquemia o trauma del sistema nervioso central.
AU749530B2 (en) * 1997-06-11 2002-06-27 Acorda Therapeutics, Inc. CNS neuroregenerative compositions and methods of use
AU8855798A (en) * 1997-07-03 1999-01-25 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Novel composition for treating, preventing and/or delaying ischemic cell death
JP3507884B2 (ja) * 2000-03-07 2004-03-15 新潟大学長 遺伝子発現を指標とする統合失調症の客観的診断法
CA2571243A1 (en) 2004-06-21 2006-01-05 The Board Of Trustees Of The Leland Stanford Junior University Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
EP1951908B1 (en) 2005-11-12 2013-08-07 The Board of Trustees of The Leland Stanford Junior University Fgf2-related methods for diagnosing and treating depression

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057494A (en) * 1988-08-03 1991-10-15 Ethicon, Inc. Method for preventing tissue damage after an ischemic episode
JP2814529B2 (ja) * 1989-03-16 1998-10-22 味の素株式会社 虚血性脳障害治療薬
WO1993008828A1 (en) * 1991-11-08 1993-05-13 Syntex-Synergen Neuroscience Joint Venture Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration

Also Published As

Publication number Publication date
EP0624094A1 (en) 1994-11-17
ES2061380B1 (es) 1995-07-01
CA2127537A1 (en) 1994-06-09
WO1994012201A1 (en) 1994-06-09
ES2061380A1 (es) 1994-12-01

Similar Documents

Publication Publication Date Title
AU623423B2 (en) A method for preventing tissue damage after an ischemic episode
JP4750947B2 (ja) 脳虚血の処置法及び脳虚血の処置のためのエリスロポエチン又はエリスロポエチン誘導体類の使用
HUT68905A (en) Pharmaceutical compositions for wound healing and treatment of fibrotic disorders and process for production of them
Zhang et al. MEPO promotes neurogenesis and angiogenesis but suppresses gliogenesis in mice with acute ischemic stroke
JPH07504205A (ja) 神経保護及び神経調節の薬剤としての繊維芽細胞増殖因子の使用
CA2519803A1 (en) Use of erythropoietin in stroke recovery
Smith et al. Effects of nicotinamide on spatial memory and inflammation after juvenile traumatic brain injury
EP1057489B1 (en) Use of midkine family proteins in the treatment of ischemic diseases
TWI327473B (en) Composition for treating a cerebrovascular disease and a method for increasing expression of erythropoietin
JP2010538006A (ja) 細胞損傷および炎症から保護し、かつ星状細胞増殖を促進する、プロテインキナーゼＣ−δ阻害剤
JP2008007512A (ja) 動脈狭窄の減弱方法
US11969522B2 (en) Use of immune modulators to improve nerve regeneration
WO1994002165A1 (en) Blood coagulation normalizer containing tcf-ii as active ingredient
US8106009B2 (en) Pharmaceutical composition for preventing or treating ischemic diseases
US20200009226A1 (en) Compositions and Methods for Treating Stroke
ES2202355T3 (es) Uso terapeutico de hemoglobina en el tratamiento de la obstruccion de vasos sanguineos.
AU2003200309B2 (en) Pharmaceutical Composition for Preventing or Treating Ischaemic Diseases
EP1681063A1 (en) Agent for improving mental disorders
KR20230047329A (ko) 졸중을 치료하기 위한 방법 및 조성물
ZA200508695B (en) Use of erythropoietin in stroke recovery
CN113727990A (zh) 短合成肽及其治疗视网膜退化性疾病和/或组织损伤的用途
JPH11199508A (ja) 臓器不全治療剤