ES2061380A1 - Empleo del factor de crecimiento fibroblastico y sus derivados como neuroprotectores y neuromoduladores. - Google Patents
Empleo del factor de crecimiento fibroblastico y sus derivados como neuroprotectores y neuromoduladores.Info
- Publication number
- ES2061380A1 ES2061380A1 ES09202360A ES9202360A ES2061380A1 ES 2061380 A1 ES2061380 A1 ES 2061380A1 ES 09202360 A ES09202360 A ES 09202360A ES 9202360 A ES9202360 A ES 9202360A ES 2061380 A1 ES2061380 A1 ES 2061380A1
- Authority
- ES
- Spain
- Prior art keywords
- fibroblast growth
- neuroprotective
- growth factors
- ischaemia
- growth factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
EMPLEO DEL FACTOR DE CRECIMIENTO FIBROBLASTICO Y SUS DERIVADOS COMO NEUROPROTECTORES Y NEUROMODULADORES FRENTE AL DAÑO PRODUCIDO POR LA ISQUEMIA Y LA REPERFUSION CEREBRAL, ASI COMO FRENTE A LA ACTIVIDAD MOTORA Y A TODOS LOS COMPUESTOS RELACIONADOS CON LA MISMA, EN AQUELLAS SITUACIONES CLINICAS QUE REQUIERAN UNA PROTECCION NEURONAL TRAS LA ISQUEMIA CEREBRAL O CAROTIDEA. IGUALMENTE, SE JUSTIFICA EL USO FARMACOLOGICO DEL FACTOR DE CRECIMIENTO DE LOS FIBROBLASTOS ACIDOS Y BASICOS, Y DE TODOS LOS COMPUESTOS RELACIONADOS CON LOS MISMOS, EN LAS SITUACIONES CLINICAS QUE REQUIERAN UNA DISMINUCION DE LA AGITACION Y DE LA AGRESIVIDAD.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09202360A ES2061380B1 (es) | 1992-11-23 | 1992-11-23 | Empleo del factor de crecimiento fibroblastico y sus derivados como neuroprotectores y neuromoduladores. |
CA002127537A CA2127537A1 (en) | 1992-11-23 | 1993-11-19 | Use of fibroblast growth factors as neuroprotective and neuromodulatory agents |
PCT/EP1993/003234 WO1994012201A1 (en) | 1992-11-23 | 1993-11-19 | Use of fibroblast growth factors as neuroprotective and neuromodulatory agents |
JP6512718A JPH07504205A (ja) | 1992-11-23 | 1993-11-19 | 神経保護及び神経調節の薬剤としての繊維芽細胞増殖因子の使用 |
EP94901818A EP0624094A1 (en) | 1992-11-23 | 1993-11-19 | Use of fibroblast growth factors as neuroprotective and neuromodulatory agents |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09202360A ES2061380B1 (es) | 1992-11-23 | 1992-11-23 | Empleo del factor de crecimiento fibroblastico y sus derivados como neuroprotectores y neuromoduladores. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2061380A1 true ES2061380A1 (es) | 1994-12-01 |
ES2061380B1 ES2061380B1 (es) | 1995-07-01 |
Family
ID=8278876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09202360A Expired - Lifetime ES2061380B1 (es) | 1992-11-23 | 1992-11-23 | Empleo del factor de crecimiento fibroblastico y sus derivados como neuroprotectores y neuromoduladores. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0624094A1 (es) |
JP (1) | JPH07504205A (es) |
CA (1) | CA2127537A1 (es) |
ES (1) | ES2061380B1 (es) |
WO (1) | WO1994012201A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5831117A (en) | 1995-01-20 | 1998-11-03 | G. D. Searle & Co. | Method of preparing retroviral protease inhibitor intermediates |
DE69634907T2 (de) * | 1995-04-25 | 2006-05-18 | Ajinomoto Co., Inc. | Fibroblastenwachstumsfragmente |
ES2201287T5 (es) * | 1996-03-22 | 2007-10-16 | Curis, Inc. | Metodo para mejorar la recuperacion funcional de la coordinacion motora, del habla o la percepcion sensorial tras una isquemia o trauma del sistema nervioso central. |
AU749530B2 (en) * | 1997-06-11 | 2002-06-27 | Acorda Therapeutics, Inc. | CNS neuroregenerative compositions and methods of use |
AU8855798A (en) * | 1997-07-03 | 1999-01-25 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Novel composition for treating, preventing and/or delaying ischemic cell death |
JP3507884B2 (ja) * | 2000-03-07 | 2004-03-15 | 新潟大学長 | 遺伝子発現を指標とする統合失調症の客観的診断法 |
CA2571243A1 (en) | 2004-06-21 | 2006-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder |
EP1951908B1 (en) | 2005-11-12 | 2013-08-07 | The Board of Trustees of The Leland Stanford Junior University | Fgf2-related methods for diagnosing and treating depression |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0357240A2 (en) * | 1988-08-03 | 1990-03-07 | Ethicon, Inc. | EGF for preventing tissue damage after ischemia |
EP0388226A2 (en) * | 1989-03-16 | 1990-09-19 | Ajinomoto Co., Inc. | Means for the treatment of senile dementia, memory disorders and related conditions |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993008828A1 (en) * | 1991-11-08 | 1993-05-13 | Syntex-Synergen Neuroscience Joint Venture | Methods for the treatment of neuronal damage associated with ischemia, hypoxia or neurodegeneration |
-
1992
- 1992-11-23 ES ES09202360A patent/ES2061380B1/es not_active Expired - Lifetime
-
1993
- 1993-11-19 EP EP94901818A patent/EP0624094A1/en not_active Withdrawn
- 1993-11-19 WO PCT/EP1993/003234 patent/WO1994012201A1/en not_active Application Discontinuation
- 1993-11-19 CA CA002127537A patent/CA2127537A1/en not_active Abandoned
- 1993-11-19 JP JP6512718A patent/JPH07504205A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0357240A2 (en) * | 1988-08-03 | 1990-03-07 | Ethicon, Inc. | EGF for preventing tissue damage after ischemia |
EP0388226A2 (en) * | 1989-03-16 | 1990-09-19 | Ajinomoto Co., Inc. | Means for the treatment of senile dementia, memory disorders and related conditions |
Also Published As
Publication number | Publication date |
---|---|
EP0624094A1 (en) | 1994-11-17 |
JPH07504205A (ja) | 1995-05-11 |
ES2061380B1 (es) | 1995-07-01 |
CA2127537A1 (en) | 1994-06-09 |
WO1994012201A1 (en) | 1994-06-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC2A | Transfer of patent |
Owner name: GUILLERMO GIMENEZ GALLEGO (TITULAR AL 50%) |