JPH07233044A - Cosmetic for preventing aging - Google Patents

Abstract

PURPOSE:To obtain a cosmetic for preventing aging, excellent in cell activating actions and having sufficient preservation stability and high safety for the skin without any irritancy. CONSTITUTION:This cosmetic is obtained by blending an extract prepared from at least one or more selected from the group consisting of galenicals Pinelliae Tuber, Mori Fructus and plants of the genus Passiflora therein. The resultant cosmetic is capable of enhancing characteristics of the aging prevention without deteriorating the safety for the human body.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION The present invention relates to at least one selected from the group consisting of crude summer herb, mulberry and Passiflora plants.
More specifically, the present invention relates to a cosmetic composition characterized by containing a plant extract of various species, more specifically, an anti-aging cosmetic composition having an activating effect on human skin cells and having an effect of improving age-related spots, wrinkles, and tarmi. It is about.

[0002]

2. Description of the Related Art Generally, age spots, wrinkles, tarmi and the like appearing on the skin surface are caused by a decline in the function of skin cells. Therefore, attention has been paid to the incorporation of a cell-activating substance into cosmetics, which has the action of activating cells whose function has declined and restoring the function and surface condition of the skin.

Conventionally, as a substance for imparting a cell activating effect which is used as a cosmetic, a single component such as vitamin, photosensitizer or allantoin or an extract component such as placenta extract, lactic acid bacterium extract or plant extract is used. .

However, the above-mentioned conventional substances and extracts having a cell-activating effect are not satisfactory in their effects, and there is a problem in the skin safety such as insufficient storage stability and irritation. There were many things.
Further, when a single component is used, there is a problem in that the production thereof often requires a process of refining, resulting in high cost.

[0005]

DISCLOSURE OF THE INVENTION The present invention solves the above-mentioned conventional problems, has a novel cell activating action, and has a novel storage stability and high safety, which is a novel anti-aging cosmetic composition. The purpose is to provide.

[0006]

[Means for Solving the Problems] As a result of intensive studies for solving the above problems, the present inventors have found that crude drug half-summer, mulberry extract and passionflower plant extract have a strong cell activating effect, The present invention can be provided.

That is, the present invention provides at least one selected from the group consisting of crude drug half-summer, mulberry and Passiflora plants.
The present invention relates to an anti-aging cosmetic composition containing an extract obtained from various plants.

[0008]

The cosmetic of the present invention can be produced by the following method. First, in the summer, a crude drug such as mulberry and a dried product or a dried pulverized product of a passionflower plant are extracted using an extraction solvent.

In this case, as the extraction solvent, alcohols such as methanol, ethanol, propanol or isopropyl alcohol, an organic solvent or water, or a mixed solvent thereof can be used. For example, it has been confirmed that extraction efficiency is good when hydrous alcohol having an alcohol concentration of 20 to 70% is used and extraction is performed at 50 ° C. for 1 hour.

After the extraction, the extracts are separated by filtration to obtain extracts, which are then concentrated under reduced pressure to dryness, and the dried extracts are collected and blended into cosmetics. You may mix | blend with cosmetics. In this case, the active ingredient can also be isolated or purified from the extract and used in this way, and thus the extract of crude drug Hanatsu, Mulberry and Passiflora exerts an excellent cell activating action at a low concentration. It has been confirmed by the present inventors that the content of 0.001 to 10.0% of this extract as an active ingredient makes it possible to obtain an anti-aging cosmetic composition having a cell activating effect.

In this case, as an antiaging cosmetic, it can be blended with a skin external cosmetic such as lotion, emulsion or cream.

As the crude drug or the dried plant product which can be used in the present invention, any of the plant fruits, leaves, stems, roots and the like can be used.

As the plant belonging to the genus Passiflora used in the present invention, one kind of Mexican plant belonging to Passiflora edulis (Scientific name: Passiflora edulis) was used.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the scope of the present invention is not limited thereto.

[0015]

Example 1 In this example, an example of a method for extracting Passiflora edulis, a plant belonging to the genus Passiflora, is shown. First of all, about 100 dried stems of a Mexican plant, Kudamonotoiso (also known as Passiflorine).
g in a mixer, put the pulverized product and 1 liter of 50% ethyl alcohol in a flask, and
Day and night extraction was performed.

After extraction, this solution was suction filtered, the obtained filtrate was concentrated under reduced pressure at 50 ° C. using an evaporator, and then the obtained concentrated solution was vacuum (freeze) dried to give about 10 g.
Of brown powder was obtained.

In the same manner as described above, 100 g of dried mulberry and dried mulberry powder, which is one of the crude drugs, is crushed,
As the dried extract, 4.0 g and 9.0 g were obtained, respectively.

[0018]

Example 2 In this example, the cell activating effect of the extract from the Mexican plant Kudamonotokei (Passiflorine) obtained in Example 1 and the crude drug Hanyu Hanatsu and Mulberry was measured by the following procedure. .

First, Eagle M containing 10% fetal bovine serum
Human-derived normal skin fibroblasts (CCD-45
SK ATCC No. CRL-1506) was inoculated to a final concentration of 5 × 10 ³ cells / ml, and 5 ml of this medium was placed in each well of a 6-well plate (FALCON), and a CO ₂ incubator (5% CO ₂ , 37
C.) for 24 hours, and then the medium was replaced with an Eagle MEM medium containing 3% fetal bovine serum, and the aqueous solution of each extract obtained in Example 1 was added to each well at a concentration of 5, 20, 50.
It was added so that the concentration became μg / ml, and the cells were further cultured for 1 week.

In this case, the medium was exchanged once during the culture, and after culturing for 1 week, trypsin (manufactured by Kojin Bio Co.)
The cells were peeled off with and the number of cells in each well was counted with a hemocytometer. At the same time, culturing without adding the sample solution was performed as a control, and the culture and cell number were measured by the same operation.

The number of cells after culturing in the well to which the sample solution was added was determined as a relative value when the number of cells in the control group after culturing was 100, and the results are also shown in Table 1.

[0022]

[Table 1] Cell growth promoting action of plant extracts

It can be seen from Table 1 that each extract of Mexican plants or herbal medicines used in this example significantly promotes cell growth even at a low concentration of 5 μg / ml, and has a cell activating effect. It was a thing.

[0024]

Example 3 In this example, an example of blending the extract of Passiflorine (Passiflorine) obtained in Example 1 with an emollient cream (cosmetics) is shown.

Emollient cream
(Wt%) Kudamonotoiso extract 1.0 Stearic acid 3.0 Sorbitan monostearate 1.5 Squalane 8.0 Vaseline 10.0 Paraffin 8.0 Lanolin 5.0 Seretun 3.5 Whale wax 5.0 Glycerin 3 0.0 Propylene glycol 3.0 Triethanolamine 1.0 Sterilizer / preservative Appropriate amount Perfume Appropriate amount Purified water Remainder

[0026]

Industrial Applicability As described above, one or more plant extracts selected from the group consisting of the herb medicine Herbaceous summer and mulberry or the plant of the genus Passiflora which is a Mexican plant are:
The cosmetic having an excellent cell activating effect and containing the extract is an excellent anti-aging cosmetic having an effect of preventing and improving age spots, wrinkles, and tarmi. In addition, since it has low toxicity to cells, it is highly safe.

Claims (1)

[Claims] 1. A cosmetic for preventing aging, which comprises an extract obtained from at least one plant selected from the group consisting of crude drug half-summer, mulberry and passionflower plants.