JPH06504671A - Neuを介して起こるトランスフォーメーションの抑制方法とそのための組成物 - Google Patents

Neuを介して起こるトランスフォーメーションの抑制方法とそのための組成物

Info

Publication number
JPH06504671A
JPH06504671A JP4502955A JP50295592A JPH06504671A JP H06504671 A JPH06504671 A JP H06504671A JP 4502955 A JP4502955 A JP 4502955A JP 50295592 A JP50295592 A JP 50295592A JP H06504671 A JPH06504671 A JP H06504671A
Authority
JP
Japan
Prior art keywords
eia
gene
neu
cells
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP4502955A
Other languages
English (en)
Japanese (ja)
Inventor
ハン,ミーン−チー
ユー,ディ−ファ
Original Assignee
ボード・オヴ・リージェンツ,ザ・ユニヴァーシティ・オヴ・テキサス・システム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ボード・オヴ・リージェンツ,ザ・ユニヴァーシティ・オヴ・テキサス・システム filed Critical ボード・オヴ・リージェンツ,ザ・ユニヴァーシティ・オヴ・テキサス・システム
Publication of JPH06504671A publication Critical patent/JPH06504671A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
JP4502955A 1990-12-04 1991-12-04 Neuを介して起こるトランスフォーメーションの抑制方法とそのための組成物 Withdrawn JPH06504671A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62146590A 1990-12-04 1990-12-04
US621,465 1990-12-04
PCT/US1991/009100 WO1992010573A1 (en) 1990-12-04 1991-12-04 Methods and compositions for the suppression of neu mediated transformation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2001234289A Division JP3323491B2 (ja) 1990-12-04 2001-08-01 Neuを介して起こる形質転換の抑制方法とそのための組成物

Publications (1)

Publication Number Publication Date
JPH06504671A true JPH06504671A (ja) 1994-06-02

Family

ID=24490270

Family Applications (2)

Application Number Title Priority Date Filing Date
JP4502955A Withdrawn JPH06504671A (ja) 1990-12-04 1991-12-04 Neuを介して起こるトランスフォーメーションの抑制方法とそのための組成物
JP2001234289A Expired - Fee Related JP3323491B2 (ja) 1990-12-04 2001-08-01 Neuを介して起こる形質転換の抑制方法とそのための組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2001234289A Expired - Fee Related JP3323491B2 (ja) 1990-12-04 2001-08-01 Neuを介して起こる形質転換の抑制方法とそのための組成物

Country Status (11)

Country Link
US (1) US5651964A (cg-RX-API-DMAC7.html)
EP (1) EP0560932B1 (cg-RX-API-DMAC7.html)
JP (2) JPH06504671A (cg-RX-API-DMAC7.html)
AT (1) ATE142261T1 (cg-RX-API-DMAC7.html)
AU (1) AU651650B2 (cg-RX-API-DMAC7.html)
CA (1) CA2096723C (cg-RX-API-DMAC7.html)
DE (1) DE69121903T2 (cg-RX-API-DMAC7.html)
DK (1) DK0560932T3 (cg-RX-API-DMAC7.html)
ES (1) ES2093248T3 (cg-RX-API-DMAC7.html)
GR (1) GR3021805T3 (cg-RX-API-DMAC7.html)
WO (1) WO1992010573A1 (cg-RX-API-DMAC7.html)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641484A (en) * 1990-12-04 1997-06-24 Board Of Regents, The University Of Texas System Methods for the suppression of neu mediated tumors by adenoviral E1A and SV40 large T antigen
US5643567A (en) * 1990-12-04 1997-07-01 Board Of Regents, The University Of Texas System Methods for the suppression of neu mediated tumors by adenoviral E1A and SV40 large T antigen
US5516631A (en) * 1992-10-13 1996-05-14 La Jolla Cancer Research Foundation Method of inhibiting replication of hyperproliferative cells
AU5962694A (en) * 1992-12-31 1994-08-15 Exemplar Corporation Producing cells for transplantation to reduce host rejection and resulting cells
US5776743A (en) 1994-09-06 1998-07-07 La Jolla Cancer Research Foundation Method of sensitizing tumor cells with adenovirus E1A
US6326356B1 (en) * 1996-10-18 2001-12-04 Board Of Regents, The University Of Texas System Suppression of neu overexpression using a mini-E1A gene
US6008202A (en) * 1995-01-23 1999-12-28 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
US6685940B2 (en) 1995-07-27 2004-02-03 Genentech, Inc. Protein formulation
US5763415A (en) * 1995-08-03 1998-06-09 John Hopkins University School Of Medicine Destruction of the epithelium of an exocrine gland in the prophylactic and therapeutic treatment of cancer
US6861506B1 (en) 1996-01-11 2005-03-01 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
US6828431B1 (en) 1999-04-09 2004-12-07 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US7241876B2 (en) 1996-01-11 2007-07-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US6656480B2 (en) 1996-01-11 2003-12-02 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
CA2250222A1 (en) * 1996-03-20 1997-09-25 Mien-Chie Hung Sensitization of her-2/neu overexpressing cancer cells to chemotherapy
US7371376B1 (en) 1996-10-18 2008-05-13 Genentech, Inc. Anti-ErbB2 antibodies
US7049410B2 (en) * 1999-05-14 2006-05-23 Majumdar Adhip P N Antibodies to a novel EGF-receptor related protein (ERRP)
US6399743B1 (en) 1999-05-14 2002-06-04 Dept. Of Veterans Affairs Isolation and characterization of a rat epidermal growth factor related protein
US9486429B2 (en) 1999-06-01 2016-11-08 Vanderbilt University Therapeutic methods employing nitric oxide precursors
US6346382B1 (en) 1999-06-01 2002-02-12 Vanderbilt University Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
US7041292B1 (en) 1999-06-25 2006-05-09 Genentech, Inc. Treating prostate cancer with anti-ErbB2 antibodies
US6949245B1 (en) 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
BR0013814A (pt) 1999-08-27 2002-04-23 Genentech Inc Métodos de tratamentos de um paciente humano suscetìvel a ou diagnosticado com uma doença com anticorpos anti-erbb2, artigos industrializados, métodos de tratamentos de câncer em pacientes humanos e usos do anticorpo anti-erbb2
US20040086903A1 (en) * 2000-12-29 2004-05-06 Jean-Jacques Lareyre Epididymal lipocalin gene and uses thereof
US20020169126A1 (en) * 2001-03-21 2002-11-14 Mien-Chie Hung Compositions and methods for inactivating the Akt oncogene and/or activating the p38 pro-apoptotic gene
US20050069918A1 (en) 2003-05-29 2005-03-31 Francois Claret JAB1 as a prognostic marker and a therapeutic target for human cancer
US20100132058A1 (en) 2004-07-23 2010-05-27 Diatchenko Luda B Methods and materials for determining pain sensitivity and predicting and treating related disorders
PT2247297T (pt) * 2008-01-31 2019-04-24 Univ Vanderbilt Tratamento terapêutico para estados pulmonares
HUE045571T2 (hu) 2008-01-31 2020-01-28 Univ Vanderbilt Koronáriás és artériás aneurizmás szubarachnoideális vérzés kezelésére szolgáló eljárások és készítmények

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394448A (en) * 1978-02-24 1983-07-19 Szoka Jr Francis C Method of inserting DNA into living cells
ES2067755T3 (es) * 1989-06-22 1995-04-01 Vestar Inc Proceso de encapsulado.
ATE237694T1 (de) * 1991-08-20 2003-05-15 Us Gov Health & Human Serv Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
US5496731A (en) * 1993-03-25 1996-03-05 Xu; Hong-Ji Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy

Also Published As

Publication number Publication date
DE69121903D1 (de) 1996-10-10
CA2096723C (en) 2006-03-28
EP0560932A1 (en) 1993-09-22
AU651650B2 (en) 1994-07-28
ATE142261T1 (de) 1996-09-15
DK0560932T3 (cg-RX-API-DMAC7.html) 1997-02-17
CA2096723A1 (en) 1992-06-05
JP2002114707A (ja) 2002-04-16
JP3323491B2 (ja) 2002-09-09
WO1992010573A1 (en) 1992-06-25
AU9146991A (en) 1992-07-08
ES2093248T3 (es) 1996-12-16
GR3021805T3 (en) 1997-02-28
US5651964A (en) 1997-07-29
DE69121903T2 (de) 1997-04-10
EP0560932B1 (en) 1996-09-04

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Effective date: 20050801