JPH0563446B2 - - Google Patents
Info
- Publication number
- JPH0563446B2 JPH0563446B2 JP20111186A JP20111186A JPH0563446B2 JP H0563446 B2 JPH0563446 B2 JP H0563446B2 JP 20111186 A JP20111186 A JP 20111186A JP 20111186 A JP20111186 A JP 20111186A JP H0563446 B2 JPH0563446 B2 JP H0563446B2
- Authority
- JP
- Japan
- Prior art keywords
- chlorhexidine gluconate
- emollient
- ethanol
- composition
- disinfectant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 52
- 239000003974 emollient agent Substances 0.000 claims description 42
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 37
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 37
- 239000000203 mixture Substances 0.000 claims description 28
- 239000000645 desinfectant Substances 0.000 claims description 24
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 11
- 239000000194 fatty acid Substances 0.000 claims description 11
- 229930195729 fatty acid Natural products 0.000 claims description 11
- 150000004665 fatty acids Chemical class 0.000 claims description 11
- HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical group CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 claims description 10
- 229940031578 diisopropyl adipate Drugs 0.000 claims description 9
- -1 polyoxyethylene Polymers 0.000 claims description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims description 8
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 7
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 150000002314 glycerols Chemical class 0.000 claims description 3
- RDOFJDLLWVCMRU-UHFFFAOYSA-N Diisobutyl adipate Chemical compound CC(C)COC(=O)CCCCC(=O)OCC(C)C RDOFJDLLWVCMRU-UHFFFAOYSA-N 0.000 claims description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical class C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 2
- 229940031769 diisobutyl adipate Drugs 0.000 claims description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 25
- 241000894006 Bacteria Species 0.000 description 22
- 239000000243 solution Substances 0.000 description 13
- 230000000249 desinfective effect Effects 0.000 description 10
- 239000012488 sample solution Substances 0.000 description 10
- 239000007864 aqueous solution Substances 0.000 description 9
- 238000011084 recovery Methods 0.000 description 8
- 238000001035 drying Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 241000191967 Staphylococcus aureus Species 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 230000037380 skin damage Effects 0.000 description 4
- 206010013786 Dry skin Diseases 0.000 description 3
- 238000000540 analysis of variance Methods 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid ester group Chemical group C(CCCCCCCCCCC)(=O)O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- HSFWRNGVRCDJHI-UHFFFAOYSA-N Acetylene Chemical compound C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000607720 Serratia Species 0.000 description 1
- 241000607715 Serratia marcescens Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 239000012888 bovine serum Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000000415 inactivating effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 235000008476 powdered milk Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20111186A JPS6357502A (ja) | 1986-08-26 | 1986-08-26 | 手指消毒用組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20111186A JPS6357502A (ja) | 1986-08-26 | 1986-08-26 | 手指消毒用組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6357502A JPS6357502A (ja) | 1988-03-12 |
| JPH0563446B2 true JPH0563446B2 (cs) | 1993-09-10 |
Family
ID=16435583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP20111186A Granted JPS6357502A (ja) | 1986-08-26 | 1986-08-26 | 手指消毒用組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6357502A (cs) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3098544B2 (ja) * | 1994-05-06 | 2000-10-16 | 鐘紡株式会社 | サイトカイン活性増強剤およびサイトカインの働きが低下した疾病の治療剤 |
| JP3636611B2 (ja) * | 1999-03-19 | 2005-04-06 | 日華化学株式会社 | 殺菌消毒剤組成物 |
| JP2002114616A (ja) * | 2000-10-12 | 2002-04-16 | Ryoso:Kk | 除菌剤とそれを用いた消毒方法 |
| AU2002258443A1 (en) * | 2002-02-28 | 2003-09-16 | Ecolab Inc. | Diester dicarboxylate antimicrobial compositions and methods employing them |
-
1986
- 1986-08-26 JP JP20111186A patent/JPS6357502A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6357502A (ja) | 1988-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |