JPH05503629A - 抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子 - Google Patents

抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子

Info

Publication number
JPH05503629A
JPH05503629A JP3501082A JP50108291A JPH05503629A JP H05503629 A JPH05503629 A JP H05503629A JP 3501082 A JP3501082 A JP 3501082A JP 50108291 A JP50108291 A JP 50108291A JP H05503629 A JPH05503629 A JP H05503629A
Authority
JP
Japan
Prior art keywords
hiv
recombinant
particles
gene
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3501082A
Other languages
English (en)
Japanese (ja)
Inventor
ハッファー，オマール，ケイ．
フ，シウ―ロク
セニア，アレン，ダブリュー
トラビス，ブルース，エム．
Original Assignee
オンコーゲン　リミテッド　パートナーシップ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オンコーゲン　リミテッド　パートナーシップ filed Critical オンコーゲン　リミテッド　パートナーシップ
Publication of JPH05503629A publication Critical patent/JPH05503629A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP3501082A 1989-11-20 1990-11-20 抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子 Pending JPH05503629A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43920589A 1989-11-20 1989-11-20
US439,205 1989-11-20

Publications (1)

Publication Number Publication Date
JPH05503629A true JPH05503629A (ja) 1993-06-17

Family

ID=23743729

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3501082A Pending JPH05503629A (ja) 1989-11-20 1990-11-20 抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子

Country Status (14)

Country Link
EP (1) EP0502105A4 (enrdf_load_html_response)
JP (1) JPH05503629A (enrdf_load_html_response)
KR (1) KR920703639A (enrdf_load_html_response)
AU (1) AU636944B2 (enrdf_load_html_response)
CA (1) CA2068713A1 (enrdf_load_html_response)
ES (1) ES2052478T1 (enrdf_load_html_response)
FI (1) FI922277A0 (enrdf_load_html_response)
GR (1) GR930300005T1 (enrdf_load_html_response)
HU (1) HUT60506A (enrdf_load_html_response)
NO (1) NO921969L (enrdf_load_html_response)
OA (1) OA09698A (enrdf_load_html_response)
TW (1) TW216446B (enrdf_load_html_response)
WO (1) WO1991007425A1 (enrdf_load_html_response)
ZA (1) ZA909302B (enrdf_load_html_response)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69034052T2 (de) * 1989-06-01 2003-09-25 Applied Biotechnology, Inc. Rekombinante vectoren , die für selbstzusammengesetzte, defekte, sich nichtselbstvermehrende viruspartikel kodieren
US5861282A (en) * 1989-10-16 1999-01-19 Whitehead Institute For Biomedical Research Non-infectious HIV particles and uses therefor
WO1991019803A1 (en) * 1990-06-19 1991-12-26 Applied Biotechnology, Incorporated Self assembled, defective, nonself-propagating viral particles
DE4124817A1 (de) * 1991-07-26 1993-01-28 Basf Ag Waessrige polymerisatdispersionen
AU672372B2 (en) * 1991-11-08 1996-10-03 Pharmacia & Upjohn Company Feline leukemia virus vaccines
CA2118026A1 (en) * 1992-04-14 1993-10-28 Guy T. Layton Induction of ctl responses
US7001759B1 (en) 1993-01-26 2006-02-21 The Trustees Of The University Of Pennsylvania Compositions and methods for delivery of genetic material
ATE302854T1 (de) 1993-01-26 2005-09-15 Univ Pennsylvania Zusammensetzungen und verfahren zur verabreichung von genetischem material
DK1473369T3 (da) 1993-01-26 2009-03-09 Univ Pennsylvania Præparater og fremgangsmåde til administration af genetisk materiale
GB9304239D0 (en) * 1993-03-01 1993-04-21 British Bio Technology Viral particles
US5858838A (en) 1998-02-23 1999-01-12 Taiwan Semiconductor Manufacturing Company, Ltd. Method for increasing DRAM capacitance via use of a roughened surface bottom capacitor plate
US6291157B1 (en) 1998-02-23 2001-09-18 Connaught Laboratories Limited Antigenically-marked non-infectious retrovirus-like particles
US5955342A (en) * 1994-08-15 1999-09-21 Connaught Laboratories Limited Non-infectious, replication-defective, self-assembling HIV-1 viral particles containing antigenic markers in the gag coding region
US6080408A (en) 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
CN1185811A (zh) * 1995-03-31 1998-06-24 H·沃尔夫 依赖于逆转录病毒样颗粒的抗原呈递系统
US6013506A (en) * 1995-06-05 2000-01-11 Wardley; Richard C. Feline leukemia virus vaccines
US6121021A (en) * 1997-12-16 2000-09-19 Connaught Laboratories Limited Constitutive expression of non-infectious HIV-like particles
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性ｈｉｖｃ型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
ATE384795T1 (de) 1998-12-31 2008-02-15 Novartis Vaccines & Diagnostic Modifizierte hiv env polypeptide
EP1980617A1 (en) 1998-12-31 2008-10-15 Novartis Vaccines and Diagnostics, Inc. Improved expression of HIV polypeptides and production of virus-like particles
CA2401974C (en) 2000-03-02 2013-07-02 Emory University Dna expression vectors and methods of use
US8623379B2 (en) 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
CN100446812C (zh) * 2001-03-08 2008-12-31 美国国有健康与人类服务部 表达修饰的hiv包膜、gag和pol基因的mva
CA2452015C (en) 2001-07-05 2012-07-03 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
KR101814857B1 (ko) 2011-04-06 2018-01-04 바이오백심 리미티드 인간에서의 hiv 질환의 예방 및/또는 치료를 위한 제약 조성물
ES2937963T3 (es) 2015-07-21 2023-04-03 Modernatx Inc Vacunas de enfermedad infecciosa
WO2018170270A1 (en) 2017-03-15 2018-09-20 Modernatx, Inc. Varicella zoster virus (vzv) vaccine
US11752206B2 (en) 2017-03-15 2023-09-12 Modernatx, Inc. Herpes simplex virus vaccine
WO2020190750A1 (en) * 2019-03-15 2020-09-24 Modernatx, Inc. Hiv rna vaccines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752565A (en) * 1986-04-07 1988-06-21 The United States Of America As Represented By The Department Of Health And Human Services Cell line producing AIDS viral antigens without producing infectious virus particles
JPH02203783A (ja) * 1989-02-02 1990-08-13 Banyu Pharmaceut Co Ltd 抗原性を有する非感染性エイズウイルス産生クローン化ヒトｔ細胞
JP3140757B2 (ja) * 1989-02-06 2001-03-05 デイナ・フアーバー・キヤンサー・インステイテユート パッケージング欠陥ｈｉｖプロウイルス、細胞系及びその使用
GB8923123D0 (en) * 1989-10-13 1989-11-29 Connaught Lab A vaccine for human immunodeficiency virus
WO1991005860A1 (en) * 1989-10-16 1991-05-02 Whitehead Institute For Biomedical Research Non-infectious hiv-1 particles and uses therefor

Also Published As

Publication number Publication date
AU636944B2 (en) 1993-05-13
WO1991007425A1 (en) 1991-05-30
HU9201659D0 (en) 1992-08-28
EP0502105A4 (en) 1993-02-24
FI922277A7 (fi) 1992-05-19
HUT60506A (en) 1992-09-28
AU6905591A (en) 1991-06-13
GR930300005T1 (enrdf_load_html_response) 1993-04-28
OA09698A (en) 1993-08-30
NO921969L (no) 1992-06-26
EP0502105A1 (en) 1992-09-09
ZA909302B (en) 1991-09-25
TW216446B (enrdf_load_html_response) 1993-11-21
NO921969D0 (no) 1992-05-19
ES2052478T1 (es) 1994-07-16
CA2068713A1 (en) 1991-05-21
FI922277A0 (fi) 1992-05-19
KR920703639A (ko) 1992-12-18

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