CA2068713A1 - Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens - Google Patents
Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogensInfo
- Publication number
- CA2068713A1 CA2068713A1 CA002068713A CA2068713A CA2068713A1 CA 2068713 A1 CA2068713 A1 CA 2068713A1 CA 002068713 A CA002068713 A CA 002068713A CA 2068713 A CA2068713 A CA 2068713A CA 2068713 A1 CA2068713 A1 CA 2068713A1
- Authority
- CA
- Canada
- Prior art keywords
- hiv
- recombinant
- particles
- gene
- nonreplicating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43920589A | 1989-11-20 | 1989-11-20 | |
| US439,205 | 1989-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2068713A1 true CA2068713A1 (en) | 1991-05-21 |
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Family Applications (1)
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|---|---|---|---|
| CA002068713A Abandoned CA2068713A1 (en) | 1989-11-20 | 1990-11-20 | Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens |
Country Status (14)
Families Citing this family (30)
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| DE69034052T2 (de) * | 1989-06-01 | 2003-09-25 | Applied Biotechnology, Inc. | Rekombinante vectoren , die für selbstzusammengesetzte, defekte, sich nichtselbstvermehrende viruspartikel kodieren |
| US5861282A (en) * | 1989-10-16 | 1999-01-19 | Whitehead Institute For Biomedical Research | Non-infectious HIV particles and uses therefor |
| WO1991019803A1 (en) * | 1990-06-19 | 1991-12-26 | Applied Biotechnology, Incorporated | Self assembled, defective, nonself-propagating viral particles |
| DE4124817A1 (de) * | 1991-07-26 | 1993-01-28 | Basf Ag | Waessrige polymerisatdispersionen |
| AU672372B2 (en) * | 1991-11-08 | 1996-10-03 | Pharmacia & Upjohn Company | Feline leukemia virus vaccines |
| CA2118026A1 (en) * | 1992-04-14 | 1993-10-28 | Guy T. Layton | Induction of ctl responses |
| US7001759B1 (en) | 1993-01-26 | 2006-02-21 | The Trustees Of The University Of Pennsylvania | Compositions and methods for delivery of genetic material |
| ATE302854T1 (de) | 1993-01-26 | 2005-09-15 | Univ Pennsylvania | Zusammensetzungen und verfahren zur verabreichung von genetischem material |
| DK1473369T3 (da) | 1993-01-26 | 2009-03-09 | Univ Pennsylvania | Præparater og fremgangsmåde til administration af genetisk materiale |
| GB9304239D0 (en) * | 1993-03-01 | 1993-04-21 | British Bio Technology | Viral particles |
| US5858838A (en) | 1998-02-23 | 1999-01-12 | Taiwan Semiconductor Manufacturing Company, Ltd. | Method for increasing DRAM capacitance via use of a roughened surface bottom capacitor plate |
| US6291157B1 (en) | 1998-02-23 | 2001-09-18 | Connaught Laboratories Limited | Antigenically-marked non-infectious retrovirus-like particles |
| US5955342A (en) * | 1994-08-15 | 1999-09-21 | Connaught Laboratories Limited | Non-infectious, replication-defective, self-assembling HIV-1 viral particles containing antigenic markers in the gag coding region |
| US6080408A (en) | 1994-08-22 | 2000-06-27 | Connaught Laboratories Limited | Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles |
| CN1185811A (zh) * | 1995-03-31 | 1998-06-24 | H·沃尔夫 | 依赖于逆转录病毒样颗粒的抗原呈递系统 |
| US6013506A (en) * | 1995-06-05 | 2000-01-11 | Wardley; Richard C. | Feline leukemia virus vaccines |
| US6121021A (en) * | 1997-12-16 | 2000-09-19 | Connaught Laboratories Limited | Constitutive expression of non-infectious HIV-like particles |
| JP2003523721A (ja) | 1998-12-31 | 2003-08-12 | カイロン コーポレイション | 抗原性ｈｉｖｃ型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用 |
| ATE384795T1 (de) | 1998-12-31 | 2008-02-15 | Novartis Vaccines & Diagnostic | Modifizierte hiv env polypeptide |
| EP1980617A1 (en) | 1998-12-31 | 2008-10-15 | Novartis Vaccines and Diagnostics, Inc. | Improved expression of HIV polypeptides and production of virus-like particles |
| CA2401974C (en) | 2000-03-02 | 2013-07-02 | Emory University | Dna expression vectors and methods of use |
| US8623379B2 (en) | 2000-03-02 | 2014-01-07 | Emory University | Compositions and methods for generating an immune response |
| CN100446812C (zh) * | 2001-03-08 | 2008-12-31 | 美国国有健康与人类服务部 | 表达修饰的hiv包膜、gag和pol基因的mva |
| CA2452015C (en) | 2001-07-05 | 2012-07-03 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| KR101814857B1 (ko) | 2011-04-06 | 2018-01-04 | 바이오백심 리미티드 | 인간에서의 hiv 질환의 예방 및/또는 치료를 위한 제약 조성물 |
| ES2937963T3 (es) | 2015-07-21 | 2023-04-03 | Modernatx Inc | Vacunas de enfermedad infecciosa |
| WO2018170270A1 (en) | 2017-03-15 | 2018-09-20 | Modernatx, Inc. | Varicella zoster virus (vzv) vaccine |
| US11752206B2 (en) | 2017-03-15 | 2023-09-12 | Modernatx, Inc. | Herpes simplex virus vaccine |
| WO2020190750A1 (en) * | 2019-03-15 | 2020-09-24 | Modernatx, Inc. | Hiv rna vaccines |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4752565A (en) * | 1986-04-07 | 1988-06-21 | The United States Of America As Represented By The Department Of Health And Human Services | Cell line producing AIDS viral antigens without producing infectious virus particles |
| JPH02203783A (ja) * | 1989-02-02 | 1990-08-13 | Banyu Pharmaceut Co Ltd | 抗原性を有する非感染性エイズウイルス産生クローン化ヒトｔ細胞 |
| JP3140757B2 (ja) * | 1989-02-06 | 2001-03-05 | デイナ・フアーバー・キヤンサー・インステイテユート | パッケージング欠陥ｈｉｖプロウイルス、細胞系及びその使用 |
| GB8923123D0 (en) * | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
| WO1991005860A1 (en) * | 1989-10-16 | 1991-05-02 | Whitehead Institute For Biomedical Research | Non-infectious hiv-1 particles and uses therefor |
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1990
- 1990-11-20 JP JP3501082A patent/JPH05503629A/ja active Pending
- 1990-11-20 AU AU69055/91A patent/AU636944B2/en not_active Ceased
- 1990-11-20 EP EP19910900526 patent/EP0502105A4/en not_active Withdrawn
- 1990-11-20 ES ES91900526T patent/ES2052478T1/es active Pending
- 1990-11-20 WO PCT/US1990/006798 patent/WO1991007425A1/en not_active Application Discontinuation
- 1990-11-20 CA CA002068713A patent/CA2068713A1/en not_active Abandoned
- 1990-11-20 ZA ZA909302A patent/ZA909302B/xx unknown
- 1990-11-20 KR KR1019920701189A patent/KR920703639A/ko not_active Ceased
- 1990-11-20 HU HU9201659A patent/HUT60506A/hu unknown
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1991
- 1991-01-12 TW TW080100246A patent/TW216446B/zh active
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1992
- 1992-05-19 FI FI922277A patent/FI922277A0/fi not_active Application Discontinuation
- 1992-05-19 OA OA60209A patent/OA09698A/en unknown
- 1992-05-19 NO NO92921969A patent/NO921969L/no unknown
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1993
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|---|---|
| AU636944B2 (en) | 1993-05-13 |
| WO1991007425A1 (en) | 1991-05-30 |
| HU9201659D0 (en) | 1992-08-28 |
| EP0502105A4 (en) | 1993-02-24 |
| FI922277A7 (fi) | 1992-05-19 |
| HUT60506A (en) | 1992-09-28 |
| AU6905591A (en) | 1991-06-13 |
| GR930300005T1 (enrdf_load_html_response) | 1993-04-28 |
| OA09698A (en) | 1993-08-30 |
| NO921969L (no) | 1992-06-26 |
| EP0502105A1 (en) | 1992-09-09 |
| ZA909302B (en) | 1991-09-25 |
| TW216446B (enrdf_load_html_response) | 1993-11-21 |
| JPH05503629A (ja) | 1993-06-17 |
| NO921969D0 (no) | 1992-05-19 |
| ES2052478T1 (es) | 1994-07-16 |
| FI922277A0 (fi) | 1992-05-19 |
| KR920703639A (ko) | 1992-12-18 |
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